J Korean Neurosurg Soc.  1994 Oct;23(10):1157-1163.

The Role of Brain SPECT for Evaluation in the Patients with Severe Head Injury

• Kwon CY
• Shin MS
• Lee KS
• Jung N
• Huh SK
• Choi JO

Abstract

Brain SPECT studies with 99mTc-HMPAO(Hexa Methyl-Propylen-Amin-Oxim) were performed in seven patients with head trauma who showed no mass lesion on brain CT(or MRI) scan and whose mean GCS were below 7 to verify the relationship between regional cerebral blood flow(rCBF), level of consciousness and clinical outcome. Initial and follow up SPECT were performed, and its percentage the r-ray counts on the portion which showed many changes in brain SPECT and its percentage were compared to the control group. Comparison of the initial and follow up studies revealed that r-ray counts and its percentage declined to very low level in one patient who died, but 5 patients whose GCS improved to 14 showed increased r-ray counts and its percentages which meant increased regional cerebral blood flow. However, how long the increased state of rCBF, which thought to be luxury perfusion, would last need to be determined. It seems to be clear that the changes of regional cerebral blood flow could be determined by comparing the rates of changed r-ray counts with 99 mTc-HMPAO SPECT.

Keyword

Regional cerebral blood flow; r-ray counts; 99mTc-HMPAO; Head trauma; Luxury perfusion

MeSH Terms

Brain*
Consciousness
Craniocerebral Trauma*
Follow-Up Studies
Head*
Humans
Perfusion
Technetium Tc 99m Exametazime
Tomography, Emission-Computed, Single-Photon*
Technetium Tc 99m Exametazime