Tuberc Respir Dis.
2002 Aug;53(2):202-208. 10.4046/trd.2002.53.2.202.
A Case of Microscopic Polyangiitis Presenting As Diffuse Alveolar Hemorrhage
- Affiliations
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- 1Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea. jeon425@dsmc.or.kr
- 2Department of Pathology, Keimyung University School of Medicine, Daegu, Korea.
- KMID: 1320436
- DOI: http://doi.org/10.4046/trd.2002.53.2.202
Abstract
- A diffuse alveolar hemorrhage is a rare manifestation in microscopic polyangiitis. Recently we experienced a case of diffuse alveolar hemorrhage associated with microscopic polyangiitis, which was diagnosed with the typical clinical manifestations, ANCA and a renal biopsy. A 71 year old female was admitted complaining of coughing and dyspnea. A chest X-ray, HRCT and BAL revealed a diffuse alveolar hemorrhage. A diffuse alveolar hemorrhage was noted during a bronchoscopy. She also had proteinuria, microscopic hematuria and mild azotemia. The renal biopsy showed necrotic glomerulonephritis without immune complex deposits or granuloma. Under the diagnosis of microscopic polyangiitis, she was treated with steroid pulse therapy, and prednisolone with cyclophosphamide subsequently. She showed marked improvement in the clinical manifestations.
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Min Jeong Jeong, Tae Wook Kim, Jun Young Im, Jae Sick Jeong, Mi Ran Park, Tae Woo Kim, Choong Won Lee
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