Tuberc Respir Dis.  2003 Dec;55(6):623-630.

Two Cases of Microscopic Polyangiitis

• Song KE
• Im SG
• Jo SK
• Jung YM
• Choi JH
• Sheen SS
• Oh YJ
• Park KJ
• Hwang SC
• Yim HE

Abstract

Microscopic polyangiitis is a systemic small-vessel vasculitis that is primarily associated with necrotizing glomerulonephritis and pulmonary capillaritis. Lung involvement is characterized by a diffuse alveolar hemorrhage. However, rarely central nervous system involvement has been reported to be occurred with the microscopic polyangiitis. Relapse of microscopic polyangiitis are reported to be more frequent than those of polyarteritis nodosa, often after a reduction or discontinuation of the therapy. We would like to report two patients with microscopic polyangiitis. One presented with clinical manifestations of both lung and central nervous system involvements and the other was a case of recurrence during steroid tapering following the steroid pulse therapy.

Keyword

Microscopic polyangiitis; ANCA; CNS vasculitis; Diffuse alveolar hemorrhage syndrome

MeSH Terms

Antibodies, Antineutrophil Cytoplasmic
Central Nervous System
Glomerulonephritis
Hemorrhage
Humans
Lung
Microscopic Polyangiitis*
Polyarteritis Nodosa
Recurrence
Vasculitis
Vasculitis, Central Nervous System
Antibodies, Antineutrophil Cytoplasmic