Korean J Hematol.
2003 Feb;38(1):55-58.
A Case of Mixed-type Autoimmune Hemolytic Anemia
- Affiliations
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- 1Department of Laboratory Medicine, Busan National University College of Medicine, Busan, Korea.
- 2Department of Internal Medicine, Busan National University College of Medicine, Busan, Korea.
Abstract
- We report a case of mixed-type autoimmune hemolytic anemia in a 73-year-old female. At first, she visited at Pusan National University Hospital, complaining of dizziness and dyspnea for 3 months. Her hemoglobin level was 5.5g/dL, so red blood transfusion was requested by her physician. In ABO blood grouping, a discrepancy between cell and serum typing was observed. Also all of donor cells for crossmatching were reactive with patient's serum. High mean corpuscular volume (MCV) value was not normalized after warming. The cold agglutinin titer was 1 : 64 at 4degrees C, and was increased up to 1 : 1,024 at room temperature and 37degrees C, suggesting mixed-type autoimmune hemolytic anemia. The patient's symptoms and signs were improved progressively with corticosteroid therapy, and also ABO discrepancy was disappeared.
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