J Korean Rheum Assoc.  2008 Dec;15(4):328-331. 10.4078/jkra.2008.15.4.328.

A Case of Systemic Lupus Erythematosus Patient with Ulcerative Colitis

• Lee KA
• Bae SC
• Bang SY
• Kim WJ
• Kim HY
• Son CN
• Lee OY
• Paik SS

• KMID: 1270164
• DOI: http://doi.org/10.4078/jkra.2008.15.4.328

Abstract

Systemic lupus erythematosus (SLE) and ulcerative colitis (UC) are both considered as systemic diseases with an abnormal immune response that depends on interactions between susceptibility genes and environmental factors. Patients with UC may share common manifestations with SLE, for example peripheral arthritis, oral ulcer. Although many autoimmune disorders tend to coexist in one patient, these two diseases are rarely associated with each other. We reported a case of a 36-year-old female where rectal bleeding was identified as ulcerative colitis. She was diagnosed as SLE prior to ulcerative colitis. There are no documented reports on SLE with ulcerative colitis in Korea.

Keyword

Systemic lupus erythematosus; Ulcerative colitis; Inflammatory bowel disease

MeSH Terms

Female
Humans

Figure

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  Fig. 1. Colonoscopic findings. Lost of vascular markings is observed and aphthous ulcers and friability are shown (A). After 6 weeks of treatment, there has been a significant improvement (B).

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  Fig. 2. Microscopic finding. The rectal mucosa shows heavy inflammatory infiltration in the lamina propria (A) and aphtous ulcer (B) with severe goblet cell depletion (H&E stain, ×200).

Reference

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