Korean J Lab Med.  2009 Oct;29(5):461-464. 10.3343/kjlm.2009.29.5.461.

Case Report of Pediatric Gastroenteritis Due to CTX-M-15 Extended-Spectrum beta-Lactamase-Producing Salmonella enterica Serotype Enteritidis

Affiliations
  • 1Department of Pediatrics, Hallym University College of Medicine, Seoul, Korea.
  • 2Department of Laboratory Medicine, Hallym University College of Medicine, Seoul, Korea. swonkeun@hallym.or.kr
  • 3Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea.

Abstract

A clinical isolate of Salmonella enterica serotype Enteritidis in Korea was found to produce the extended-spectrum beta-lactamase CTX-M-15. The isolate was recovered in 2008 from the stool of a 3-yr-old boy with gastroenteritis. This isolate was found to be resistant to multiple drugs, including ampicillin, piperacillin, cefotaxime, ceftazidime, cefepime, and aztreonam. The resistance to cefotaxime was transferred by conjugation to recipient Escherichia coli J53. The patient was eventually successfully treated with trimethoprim-sulfamethoxazole. This is the first report of the bla (CTX-M-15) gene in S. enterica serotype Enteritidis in Korea.

Keyword

Salmonella enterica; CTX-M-15; Korea

MeSH Terms

Child, Preschool
Gastroenteritis/diagnosis/*microbiology
Humans
Male
Salmonella enteritidis/genetics/*isolation & purification
Serotyping
beta-Lactamases/*genetics

Cited by  1 articles

Comparison of Clinical and Laboratory Standards Institute and European Committee on Antimicrobial Susceptibility Testing Breakpoints for β-Lactams in Enterobacteriaceae Producing Extended-Spectrumβ-Lactamases and/or Plasmid-Mediated AmpCβ-Lactamases
Wonkeun Song, Min-Jeong Park, Han-Sung Kim, Jae-Seok Kim, Hyun Soo Kim, Kyu Man Lee
Korean J Clin Microbiol. 2011;14(1):24-29.    doi: 10.5145/KJCM.2011.14.1.24.


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