Korean J Radiol.  2008 Aug;9(4):340-347. 10.3348/kjr.2008.9.4.340.

Radiofrequency Ablation Treatment for Renal Cell Carcinoma: Early Clinical Experience

• Park SH
• Yoon SK
• Cho JH
• Oh JY
• Nam KJ
• Kwon HJ
• Kim SY
• Kang MJ
• Choi S
• Sung GT

• KMID: 1076460
• DOI: http://doi.org/10.3348/kjr.2008.9.4.340

Abstract

OBJECTIVE
To evaluate the early clinical experience associated with radiofrequency (RF) ablation in patients with renal cell carcinoma (RCC). MATERIALS AND METHODS: The RF ablation treatment was performed on 17 tumors from 16 patients (mean age, 60.5 years; range, 43-73 years) with RCC. The treatment indications were localized, solid renal mass, comorbidities, high operation risk, and refusal to perform surgery. All tumors were treated by a percutaneous CT (n = 10), followed by an US-guided (n = 2), laparoscopy-assisted US (n = 2), and an open (n = 2) RF ablation. Furthermore, patients underwent a follow-up CT at one day, one week, one month, three and six months, and then every six months from the onset of treatment. We evaluated the technical success, technical effectiveness, ablation zone, benign periablation enhancement, irregular peripheral enhancement, and complications. RESULTS: All 17 exophytic tumors (mean size, 2.2 cm; range, 1.1-5.0 cm) were completely ablated. Technical success and effectiveness was achieved in all cases and the mean follow-up period was 23.8 months (range, 17-33 months). A local recurrence was not detected in any of the cases; however, five patients developed complications as a result of treatment, including hematuria (n = 2), mild thermal injury of the psoas muscle (n = 1), mild hydronephrosis (n = 1), and fistula formation (n = 1). CONCLUSION: The RF ablation is an alternative treatment for exophytic RCCs and represents a promising treatment for some patients with small RCCs.

Keyword

Radiofrequency ablation; Renal tumors; Kidney tumors

MeSH Terms

Adult
Aged
Carcinoma, Renal Cell/radiography/*surgery
*Catheter Ablation/adverse effects
Female
Humans
Kidney Neoplasms/radiography/*surgery
Male
Middle Aged
Tomography, X-Ray Computed

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