- Identification of a Novel Putative Protein Serine / Threonine Kinase, PK38, in Normal Human Keratinocytes
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Gil MC, Ha HJ
- KMID: 1548220
- Korean J Immunol.
- 1997 Jun;19(2):189-196.
No abstract available. -
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- Action Mechanisms of Hormone Binding to Cell Surface Receptors: 3) TGF-beta; Binding to Serine-threonine Kinase Receptors and Action Mechanisms
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Hahm KB
- KMID: 2199641
- J Korean Soc Endocrinol.
- 2000 Jun;15(3):353-366.
No Abstract Available. -
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- Anti-Helicobacter pylori, Anti-apoptotic, and Cytoprotective Effects of Threonine Synthesized from Corynebacterium glutamicum in Gastric Epithelial Cells
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An JM, Kim YS, Hong YG, Hah BS, Sohn MS, Hahm KB
- KMID: 2469316
- Korean J Helicobacter Up Gastrointest Res.
- 2019 Dec;19(4):245-256.
- doi: 10.7704/kjhugr.2019.0011
BACKGROUND/AIMS: Among irritants causing gastric ulcer, Helicobacter pylori (H. pylori) might be pivotal, after which eradication became essential way in either inhibiting ulcerogenesis or preventing ulcer recurrence. Since threonine is... -
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- Inhibition of MUC1 biosynthesis via threonyl-tRNA synthetase suppresses pancreatic cancer cell migration
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Jeong SJ, Kim JH, Lim BJ, Yoon I, Song JA, Moon HS, Kim D, Lee DK, Kim S
- KMID: 2438354
- Exp Mol Med.
- 2018 Jan;50(1):e424.
- doi: 10.1038/emm.2017.231
Mucin1 (MUC1), a heterodimeric oncoprotein, containing tandem repeat structures with a high proportion of threonine, is aberrantly overexpressed in many human cancers including pancreatic cancer. Since the overall survival rate... -
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- A Case of Glucose-6-phosphate dehydrogenase Riley Causing Hemolytic Anemia
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Park SW, Lee HJ, Lee W, Whang KT
- KMID: 2083383
- Korean J Hematol.
- 1999 May;34(2):334-337.
A glucose-6-phoshate dehydrogenase variant called G6PD Riley was detected in an Korean boy with nonspherocytic hemolytic anemia. Using polymerase chain reaction based single-strand conformation polymorphism (PCR-SSCP) followed by DNA sequence... -
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- Chemical Ingredients of Cordyceps militaris
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Hur H
- KMID: 1487351
- Mycobiology.
- 2008 Dec;36(4):233-235.
- doi: 10.4489/MYCO.2008.36.4.233
Medicinal mushrooms, including Cordyceps militaris, have received attention in Korea because of their biological activities. In the fruiting body and in corpus of C. militaris, the total free amino acid... -
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- Association between FABP2 Gene Polymorphism and Energy Metabolism in Normal Korean
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Yun SK, Kim CH, Kim YS, Byun DW, Suh KI, Yoo MH, Kim GB
- KMID: 2331689
- J Korean Diabetes Assoc.
- 1998 Dec;22(4):457-466.
BACKGROUND: The human intestinal fatty acid binding protein (FABP2) locus has been proprosed to be a major candidate gene in determining insulin resistance. It has been hypothesized that alanine to... -
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- Peutz-Jeghers syndrome with germline mutation of STK11
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Chae HD, Jeon CH
- KMID: 2167111
- Ann Surg Treat Res.
- 2014 Jun;86(6):325-330.
- doi: 10.4174/astr.2014.86.6.325
Peutz-Jeghers syndrome (PJS), also known as periorificial lentiginosis, is a rare autosomal dominant inherited disease with an incidence of 1/200,000 live-borns. Mutations in the serine-threonine kinase 11 (STK11) gene are... -
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- Resistance to thyroid hormone due to a novel mutation of thyroid hormone receptor beta gene
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Lee JH, Kim EY
- KMID: 1769358
- Ann Pediatr Endocrinol Metab.
- 2014 Dec;19(4):229-231.
- doi: 10.6065/apem.2014.19.4.229
Resistance to thyroid hormone (RTH) is a rare inherited syndrome characterized by diminished response of the target tissue to thyroid hormone caused, in the majority of cases, by mutation of... -
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- Alternative Polyadenylation in Human Diseases
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Chang JW, Yeh HS, Yong J
- KMID: 2406184
- Endocrinol Metab.
- 2017 Dec;32(4):413-421.
- doi: 10.3803/EnM.2017.32.4.413
Varying length of messenger RNA (mRNA) 3′-untranslated region is generated by alternating the usage of polyadenylation sites during pre-mRNA processing. It is prevalent through all eukaryotes and has emerged as... -
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- Genes Involved in the Biosynthesis and Transport of Acinetobactin in Acinetobacter baumannii
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Hasan T, Choi CH, Oh MH
- KMID: 2053330
- Genomics Inform.
- 2015 Mar;13(1):2-6.
- doi: 10.5808/GI.2015.13.1.2
Pathogenic bacteria survive in iron-limited host environments by using several iron acquisition mechanisms. Acinetobacter baumannii, causing serious infections in compromised patients, produces an iron-chelating molecule, called acinetobactin, which is composed... -
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- Sequence Analysis and Potential Action of Eukaryotic Type Protein Kinase from Streptomyces coelicolor A3(2)
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Roy DR, Chandra SB
- KMID: 2166321
- Genomics Inform.
- 2008 Mar;6(1):44-49.
Protein kinase C (PKC) is a family of kinases involved in the transduction of cellular signals that promote lipid hydrolysis. PKC plays a pivotal role in mediating cellular responses to... -
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- Phosphorylation of chicken protein tyrosine phosphatase 1 by casein kinase II in vitro
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Jung EJ, Kang KR, Kang YS
- KMID: 1532667
- Exp Mol Med.
- 1997 Dec;29(4):229-233.
The phosphorylation and dephosphorylation of proteins on tyrosyl residues are key regulatory mechanisms of cell growth and signal transduction and are controlled by opposing activities of protein tyrosine kinases and... -
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- Pim-1: A serine/threonine kinase with a role in cell survival, proliferation, differentiation and tumorigenesis
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Wang Z, Bhattacharya N, Weaver M, Petersen K, Meyer M, Gapter L, Magnuson N
- KMID: 1119212
- J Vet Sci.
- 2001 Dec;2(3):167-179.
Pim-1 belongs to a family of serine/threonine protein kinases that are highly conserved through evolution in multicellular organisms. Originally identified from moloney murine leukemia virus (MuLV)-induced T-cell lymphomas in mice,... -
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- Reserpine treatment activates AMP activated protein kinase (AMPK)
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Park R, Lee KI, Kim H, Jang M, Ha TK, Oh WK, Park J
- KMID: 2393795
- Nat Prod Sci.
- 2017 Sep;23(3):157-161.
- doi: 10.20307/nps.2017.23.3.157
Reserpine is a well-known medicine for the treatment of hypertension, however the role of reserpine in cell signaling is not fully understood. Here, we report that reserpine treatment induces the... -
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- Association between Serine/Threonine Kinase 39 Gene Polymorphism, Hypertension, and Other Cardiovascular Risk Factors in Koreans
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Shin DJ, Lee SH, Park S, Jang Y
- KMID: 1722996
- Korean Circ J.
- 2013 Jan;43(1):13-22.
- doi: 10.4070/kcj.2013.43.1.13
BACKGROUND AND OBJECTIVES: Although the association between single nucleotide polymorphisms (SNPs) of Serine/Threonine Kinase 39 (STK39) and hypertension has been reported, the prior studies have been inconsistent. The aim of... -
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- TGF-beta(1) Genotyping in Kidney Transplantation
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Jeon DS
- KMID: 2226025
- Korean J Clin Pathol.
- 2001 Jun;21(3):225-230.
BACKGROUND: Transforming growth factor-beta1 (TGF-beta(1)) is a multifunctional cytokine that is involved in the development of the features of chronic rejection in organ transplantation, namely fibrosis. The severity and frequency... -
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- Mutations at the Gene Encoding the 'a' Determinant of HBsAg in Chronic Hepatitis B Patients with Concurrent HBsAg and Anti-HBs Positivity
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Park JW, Yoon JH, Hwang YJ, Lee HS, Kim CY
- KMID: 2084726
- Korean J Gastroenterol.
- 1997 Feb;29(2):182-191.
BACKGROUND/AIMS: A humoral escape mutant of hepatitis B virus(HBV) having mutations at HBsAg a' determinant has been found in patients with concurrent HBsAg and anti-HBs in sera. This study was... -
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- Transcriptional Profiling of an Attenuated Salmonella Typhimurium ptsI Mutant Strain Under Low-oxygen Conditions using Microarray Analysis
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Lim S, Han A, Kim D, Seo HS
- KMID: 2068735
- J Bacteriol Virol.
- 2015 Sep;45(3):200-214.
- doi: 10.4167/jbv.2015.45.3.200
Salmonella causes a wide variety of diseases ranging from mild diarrhea to severe systemic infections, such as like typhoid fever, in multiple organisms, ranging from mice to humans. A lack... -
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- Therapeutic Effects of Amino Acids in Liver Diseases: Current Studies and Future Perspectives
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Lee DY, Kim EH
- KMID: 2454667
- J Cancer Prev.
- 2019 Jun;24(2):72-78.
- doi: 10.15430/JCP.2019.24.2.72
Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver and the third most common cause of cancer-related death worldwide. HCC is caused by infection of hepatitis... -
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