- Study on Association between an H-RAS Gene Polymorphism and Gastric Cancer Development
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Oh JH
- KMID: 1775869
- Korean J Gastroenterol.
- 2010 Aug;56(2):121-122.
- doi: 10.4166/kjg.2010.56.2.121
No abstract available. -
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- N-ras Mutation Detection by Pyrosequencing in Adult Patients with Acute Myeloid Leukemia at a Single Institution
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Jeong JH, Park SH, Park MJ, Kim MJ, Kim KH, Park PW, Seo YH, Lee JH, Park J, Hong J, Ahn JY
- KMID: 1781320
- Ann Lab Med.
- 2013 May;33(3):159-166.
- doi: 10.3343/alm.2013.33.3.159
BACKGROUND: N-ras mutations are one of the most commonly detected abnormalities of myeloid origin. N-ras mutations result in a constitutively active N-ras protein that induces uncontrolled cell proliferation and inhibits... -
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- Concomitance of P-gp/LRP Expression with EGFR Mutations in Exons 19 and 21 in Non-Small Cell Lung Cancers
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Wei H, Lu W, Li M, Zhang Q, Lu S
- KMID: 2466351
- Yonsei Med J.
- 2016 Jan;57(1):50-57.
- doi: 10.3349/ymj.2016.57.1.50
PURPOSE: Traditional chemotherapy is the main adjuvant therapy for the treatment of non-small cell lung cancer (NSCLC). However, the emergence of multi-drug resistance (MDR) has greatly restricted the curative effect... -
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- ANT2 suppression by shRNA restores miR-636 expression, thereby downregulating Ras and inhibiting tumorigenesis of hepatocellular carcinoma
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Jang JY, Lee YS, Jeon YK, Lee K, Jang JJ, Kim CW
- KMID: 2154222
- Exp Mol Med.
- 2013 Jan;45(1):e3.
MicroRNAs (miRNAs) participate in diverse biological functions and carcinogenesis by inhibiting specific gene expression. We previously reported that suppression of adenine nucleotide translocase 2 (ANT2) by using the short hairpin... -
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- Study on Association between an H-RAS Gene Polymorphism and Gastric Cancer Development
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Song HJ, Pyun JA, Lee KJ, Cho SW, Kwack KB
- KMID: 1775861
- Korean J Gastroenterol.
- 2010 Aug;56(2):78-82.
- doi: 10.4166/kjg.2010.56.2.78
BACKGROUND/AIMS: Oncogenic RAS gene mutations have been frequently observed in many tumor types, and their associations with various cancers were reported. This study was conducted to evaluate the association between... -
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- Activation of KRAS promotes the mesenchymal features of basal-type breast cancer
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Kim RK, Suh Y, Yoo KC, Cui YH, Kim H, Kim MJ, Kim IG, Lee SJ
- KMID: 2155402
- Exp Mol Med.
- 2015 Jan;47(1):e137.
- doi: 10.1038/emm.2014.99
Basal-type breast cancers are among the most aggressive and deadly breast cancer subtypes, displaying a high metastatic ability associated with mesenchymal features. However, the molecular mechanisms underlying the maintenance of... -
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- LIN28B confers radio-resistance through the posttranscriptional control of KRAS
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Jeong SH, Wu HG, Park WY
- KMID: 1099867
- Exp Mol Med.
- 2009 Dec;41(12):912-918.
- doi: 10.3858/emm.2009.41.12.097
To screen the differentially expressed microRNAs related to radio-resistance, we compared the microRNA profiles of lung cancer cells with different responses to ionizing radiation (IR). Of 328 microRNAs in microarray,... -
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- The Impact of Cigarette Smoking on the Frequency of and Qualitative Differences in KRAS Mutations in Korean Patients with Lung Adenocarcinoma
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Kim HR, Ahn JR, Lee JG, Bang DH, Ha SJ, Hong YK, Kim SM, Nam KC, Rha SY, Soo RA, Riely GJ, Kim JH, Cho BC
- KMID: 2158219
- Yonsei Med J.
- 2013 Jul;54(4):865-874.
- doi: 10.3349/ymj.2013.54.4.865
PURPOSE: This study was designed to determine the relationship of cigarette smoking to the frequency and qualitative differences among KRAS mutations in lung adenocarcinomas from Korean patients. MATERIALS AND METHODS: Detailed... -
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- Mutational Analysis of KRAS, BRAF, and TP53 Genes of Ovarian Serous Carcinomas in Korean Women
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Cho YH, Kim DY, Kim JH, Kim YM, Kim KR, Nam JH, Kim YT
- KMID: 2396071
- Yonsei Med J.
- 2009 Apr;50(2):266-272.
PURPOSE: To assess the prevalence of KRAS, BRAF, and TP53 mutations in cases of low-grade and high-grade serous carcinomas and to evaluate the clinical outcomes of these morphologically distinct carcinomas.... -
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- Detection of EGFR and KRAS Mutation by Pyrosequencing Analysis in Cytologic Samples of Non-Small Cell Lung Cancer
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Lee SE, Lee SY, Park HK, Oh SY, Kim HJ, Lee KY, Kim WS
- KMID: 2373749
- J Korean Med Sci.
- 2016 Aug;31(8):1224-1230.
- doi: 10.3346/jkms.2016.31.8.1224
EGFR and KRAS mutations are two of the most common mutations that are present in lung cancer. Screening and detecting these mutations are of issue these days, and many different... -
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