- Structure and Function Analysis of alpha-MSH Analogues
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Lim SK, Lee SC, Lee WT, Lee JH, Nam SY, Kim KR, Lee HC, Huh KB
- KMID: 2331132
- J Korean Soc Endocrinol.
- 1999 Mar;14(1):18-26.
No abstract available. -
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- The Effect of alpha-MSH on the Morphologic Changes, Survival, and Melanization of Cultured Human Melanocytes
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Kim HS, Lee MH
- KMID: 2230573
- Korean J Dermatol.
- 1998 Apr;36(2):280-285.
BACKGROUND: The effects of melanocyte stimulating hormone(MSH) on the integument of many species, including mammals, are well known. The significance of MSH as a physiological regulator of cutaneous pigmentation in... -
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- The Expression of the alpha-Melanocyte Stimulating Hormone (alpha-MSH) and Melanocortin-1 Receptor (MC1R) in the Epidermis of the Vitiligo
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Cha YC, Lee HJ, Lee SJ, Na GY, Chung SL
- KMID: 2302963
- Korean J Dermatol.
- 2003 Jun;41(6):690-695.
BACKGROUND: Vitiligo is a skin disease that is characterized by the loss of cutaneous pigmentation. alpha-Melanocyte stimulating hormone (alpha-MSH) is a neuroimmunomodulating peptide derived from proopiomelanocortin, and melanocortin-1 receptor (MC1R)... -
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- Alpha-Melanocyte Stimulating Hormone Protects Pancreatic Islet Dysfunction by Peripheral Blood Mononuclear Cells in vitro
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Jung EJ, Han DJ, Chang SH, Lim DG, Wee YM, Kim JH, Kim YH, Koo SK, Choi M, Park KT, Kim SC
- KMID: 2003579
- J Korean Soc Transplant.
- 2006 Jun;20(1):41-48.
PURPOSE: The alpha-melanocyte-stimulating hormone (alpha-MSH) has been shown to interact with various cells of the immune and inflammatory system and down-regulate either the production or the action of the pro-inflammatory... -
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- The Effect of alpha MSH Analogues on Rat Bones
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Lim SK, Li SZ, Rhee Y, Chung SS, Jin YJ, Yook JI
- KMID: 1122009
- Yonsei Med J.
- 2002 Aug;43(4):500-510.
- doi: 10.3349/ymj.2002.43.4.500
Melanocortin is the downstream mediator of leptin signaling and absence of leptin signaling in ob/ob and db/db mice revealed the enhancement of bone formation through the central regulation. While alpha-melanocyte-stimulating... -
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- Drug Induced Cerebral Proerectile Effect in Anesthethetized Rats
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Park HJ, Nam JK, Park NC
- KMID: 2298601
- Korean J Androl.
- 2004 Dec;22(3):132-140.
PURPOSE: To examine the centrally elicited erectile effects of alpha-MSH, oxytocin, prostagladin E1, and anabolic steroids after intracerebroventricular administration. MATERIALS AND METHODS: We used anesthetized male Sprague-Dawley rats. After intracerebroventricular... -
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- The Effect of alpha-MSH on Tumor Necrosis Factor-alpha and NFkappaB Activation in Cultured Human Proximal Tubular Cells during Simulated Ischemia
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Lee SY, Kim SW, Jo SK, Kwon YJ, Cha DR, Cho WY, Kim HK
- KMID: 2079271
- Korean J Nephrol.
- 2003 Jan;22(1):43-52.
BACKGROUND: Tumor necrosis factor a (TNF), potent proinflammatory cytokine, may be related with ischemia/reperfusion injury induced tubular cell inflammation and apoptosis. We examined TNF and its major nuclear transcriptional factor,... -
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- The Effect of alpha-Melanocyte Stimulating Hormone on Renal Ischemia Reperfusion Injury
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Yom CK, Jin JW, Chung KY, Sung SH, Han KW, Kang ES, Kim YS
- KMID: 2003580
- J Korean Soc Transplant.
- 2006 Jun;20(1):49-54.
PURPOSE: In ischemia-reperfusion induced renal injuries, cytokines, chemoattractant chemokines, adhesion molecules and nitric oxide play an important role. alpha-Melanocyte stimulating hormone (alpha-MSH) is a potent anti-inflammatory cytokine so the therapeutic... -
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- The Effect of alpha-MSH on Long-term Histologic Changes after Acute Ischemic Kidney Injury in Rats
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Lee SY, Cho WY, Kim HK, Won NH
- KMID: 2079443
- Korean J Nephrol.
- 2005 Mar;24(2):191-203.
BACKGROUND: Ischemic acute renal failure (ARF) is increasingly recognized as involving chronic functional and structural sequelae. Ischemia reperfusion injury (I/R) plays a major role in delayed graft function and long-term... -
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- Altered Expression of Renal AQP1, AQP2 and NHE3 in Puromycin Aminonucleoside Induced Nephrotic Syndrome: Intervention by Alpha-MSH Treatment
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Kwon TH, Kim KK
- KMID: 2079268
- Korean J Nephrol.
- 2003 Jan;22(1):10-23.
BACKGROUND: We examined whether puromycin aminonucleoside (PAN)-induced nephrotic syndrome (NS) is associated with altered renal handling of water and sodium along with changes of renal abundance of aquaporins (AQP1 and... -
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- Expression of signal transducing G proteins in human melanoma cell lines
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Lee ES, Kang WH, Jin YH, Juhnn YS
- KMID: 1532666
- Exp Mol Med.
- 1997 Dec;29(4):223-227.
Some malignant melanoma cells regress spontaneously by terminal differentiation, and understanding the mechanisms of this spontaneous regression can contribute to the development of a new therapy not only for melanoma... -
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- Effects of alpha-melanocyte stimulating hormone on the expression of intercellular adhesion molecule-1 and renal function in acute ischemic renal failure in rats
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Jo SK, Yoon JW, Cha DR, Cho WY, Kim HK, Won NH, Yoon SY, Chang KH
- KMID: 2306159
- Korean J Med.
- 2000 Dec;59(6):641-650.
BACKGROUND: Acute renal failure is a reversible process in majority of cases but mechanisms of renal injury or recovery are poorly understood. Recently neutrophil infiltration is reported to potentiate inflammatory... -
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- Induction of Melanogenesis by Rapamycin in Human MNT-1 Melanoma Cells
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Hah YS, Cho HY, Lim TY, Park DH, Kim HM, Yoon J, Kim JG, Kim CY, Yoon TJ
- KMID: 2434679
- Ann Dermatol.
- 2012 May;24(2):151-157.
BACKGROUND: Melanogenesis is one of the characteristic parameters of differentiation in melanocytes and melanoma cells. Specific inhibitors of phosphatidylinositol 3-kinase (PI3K), such as wortmannin and LY294002, stimulate melanin production in... -
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- Effect of weight loss on cerebrospinal Fluid and Plasma Concentrations of NPY, alpha -MSH and leptin in Obese Women
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Nam SY, Kim KW, Lee JH, Lee SJ, Kim KR, Song YD, Lim SK, Lee HC, Huh KB
- KMID: 2199799
- J Korean Soc Endocrinol.
- 2001 Apr;16(2):199-209.
BACKGROUND: Although leptin and its principal mediators, neuropeptide Y (NPY) and -melanocyte stimulating hormone (MSH) are postulated to play a pivotal role in the energy balance in experimental animals,... -
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- -Melanocyte Stimulating Hormone (MSH) decreases cyclosporine A induced apoptosis in cultured human proximal tubular cells
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Jo SK, Lee SY, Han SY, Cha DR, Cho WY, Kim HK, Won NH
- KMID: 2157569
- J Korean Med Sci.
- 2001 Oct;16(5):603-609.
- doi: 10.3346/jkms.2001.16.5.603
The pathogenesis of chronic cyclosporine A (CsA) nephrotoxicity has not been elucidated, but apoptosis is thought to play an important role in CsA induced tubular atrophy. Recently Fas-Fas ligand system... -
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- Development of intestinal ischemia/reperfusion-induced acute kidney injury in rats with or without chronic kidney disease: Cytokine/chemokine response and effect of alpha-melanocyte-stimulating hormone
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Skottx M, Norregaard R, Birke-Sorensen H, Palmfeldt , Kwon TH, Jonassen T, Frokiaer J, Nielsen S
- KMID: 2224271
- Kidney Res Clin Pract.
- 2014 Jun;33(2):79-88.
BACKGROUND: The primary aim of the study was to investigate the cytokine/chemokine response in the kidney, lung, and liver following acute kidney injury (AKI). The secondary aim was to test... -
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- Effects of alpha-Melanocyte Stimulating Hormone on Apoptosis and Fas Expression in Ischemic Renal Injury in Rats
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Jo SK, Yoon JW, Cha DR, Cho WY, Kim HK, Won NH, Yoon SY, Chang KH, Kim KW
- KMID: 2254515
- Korean J Nephrol.
- 2000 Sep;19(5):784-794.
Apoptosis frequently occurs in acute renal injury but molecular mechanisms responsible for this distinct form of cell death are largely unknown. Fas belongs to the TNF/nerve growth factor superfamily and... -
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- Superoxide Dismutase 1 Inhibits Alpha-Melanocyte Stimulating Hormone and Ultraviolet B-Induced Melanogenesis in Murine Skin
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Oh CT, Lee D, Koo K, Lee J, Yoon HS, Choi YM, Kwon TR, Kim BJ
- KMID: 2264861
- Ann Dermatol.
- 2014 Dec;26(6):681-687.
- doi: 10.5021/ad.2014.26.6.681
BACKGROUND: Over the last decade, the incidence of ultraviolet B (UVB)-related skin problems has increased. Oxidative stress caused by UVB induces the secretion of melanocyte growth and activating factors from... -
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- Expression of Human Melanocyte Markers in PMA-containing Medium and Physiologic Mitogen-containing Medium
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Yoon TJ, Kim KT, Kim KH, Lee JW, Lee MH
- KMID: 2248994
- Korean J Dermatol.
- 2006 May;44(5):579-585.
BACKGROUND: There are many growth media for cultivation of human melanocytes (MGM), depending on the supplements added, and the growth of cells is closely related to these components. To understand... -
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- Inhibitory Effects of Resveratrol on Melanin Synthesis in Ultraviolet B-Induced Pigmentation in Guinea Pig Skin
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Lee TH, Seo JO, Baek SH, Kim SY
- KMID: 2048328
- Biomol Ther.
- 2014 Jan;22(1):35-40.
Resveratrol is a polyphenolic compound found in various natural products such as grapes and berries and possesses anti-cancer, anti-hyperlipidemia, and anti-aging properties. Recently, it has been reported that resveratrol inhibits... -
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