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Growth Inhibitory and Pro-Apoptotic Effects of Hirsuteine in Chronic Myeloid Leukemia Cells through Targeting Sphingosine Kinase 1

Gao S, Guo T, Luo S, Zhang Y, Ren Z, Lang X, Hu G, Zuo D, Jia W, Kong D, Yu H, Qiu Y

Chronic myeloid leukemia (CML) is a slowly progressing hematopoietic cell disorder. Sphingosine kinase 1 (SPHK1) plays established roles in tumor initiation, progression, and chemotherapy resistance in a wide range of...
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Establishment of a novel experimental model of infected anal fistula in rat

Zhao M, Wang A, Zhang L, Yu H

Refractory Crohn’s-like enterocutaneous fistula indicates the aggressive manifestation and lead to poor prognosis of patients. The development of multidisciplinary strategies for fistula administration largely subjects to the deficiency of animal...
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The Biocompatibility of Multi-Source Stem Cells and GelatinCarboxymethyl Chitosan-Sodium Alginate Hybrid Biomaterials

Wang X, Li S, Yu H, Lv J, Fan M, Wang X, Wang X, Liang Y, Mao L, Zhao Z

BACKGROUND: Nowadays, biological tissue engineering is a growing field of research. Biocompatibility is a key indicator for measuring tissue engineering biomaterials, which is of great significance for the replacement and...
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Three Cases of Anti-LW Antibody Identification at a Tertiary Hospital in Korea

Chae S, Kim KB, Yu H, Choi HJ, Jekarl DW, Lim J, Kim Y

The Landsteiner–Wiener (LW) antigen is a type of red blood cell antigen. Anti-LW appears in various situations, including alloantibodies, autoantibodies, and even transiently occurring antibodies. Anti-LW has similar characteristics to...
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In silico screening method for non‑responders to cardiac resynchronization therapy in patients with heart failure: a pilot study

Hwang M, Uhm J, Park M, Shim E, Lee C, Oh J, Yu H, Kim T, Joung B, Pak H, Kang S, Lee M

Background: Cardiac resynchronization therapy (CRT) is an effective treatment option for patients with heart failure (HF) and left ventricular (LV) dyssynchrony. However, the problem of some patients not responding to CRT...
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Morphological and Molecular Phylogenetic Data of the Chinese Medicinal Fungus Cordyceps liangshanensis Reveal Its New Systematic Position in the Family Ophiocordycipitaceae

Wang Y, Dai YD, Yang ZL, Guo R, Wang YB, Yang ZL, Ding L, Yu H

A cordycipitoid fungus infecting Hepialidae sp. in Nepal was supposed to be identical to Cordyceps liangshanensis, originally described from southwestern China, and thus, transferred to the genus Metacordyceps or Papiliomyces...
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Baseline Total Metabolic Tumor Volume and Total Lesion Glycolysis Measured on 18F-FDG PET-CT Predict Outcomes in T-Cell Lymphoblastic Lymphoma

Feng X, Wen X, Li L, Sun Z, Li X, Zhang L, Wu J, Fu X, Wang X, Yu H, Ma X, Zhang X, Xie X, Han X, Zhang M

Purpose There is no optimal prognostic model for T-cell lymphoblastic lymphoma (T-LBL). Here, we discussed the predictive value of total metabolic tumor volume (TMTV) and total lesion glycolysis (TLG) measured...
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Multigene Phylogeny and Morphology of Ophiocordyceps alboperitheciata sp. nov., A New Entomopathogenic Fungus Attacking Lepidopteran Larva from Yunnan, China

Fan Q, Wang YB, Zhang GD, Tang DX, Yu H

A new fungus, Ophiocordyceps alboperitheciata, parasitic on the larva of Noctuidae (Lepidoptera) was identified from a survey of entomopathogenic fungi in Kunming Wild Duck Forest Park, Yunnan Province, China. It...
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Risk for osteoporotic fractures in patients with atrial fibrillation using different oral anticoagulants

Kim D,  Yang P,  Sung J, Jang ,E, Yu H, Kim T,  Uhm J, Kim J,  Pak H,  Lee M,  Lip G,  Joung B

Background: We aimed to investigate the comparative risk of fracture among patients with atrial fibrillation (AF) treated with warfarin or non-vitamin K antagonist oral anticoagulants (NOACs). Methods: Using the Korean National...
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Rare ABO Allele Encoding Glycosyltransferase with Dual Specificity Found in a Cambodian Individual with the A 2 B Phenotype

Yu H, Chung YN, Kim TY, Suh E, Choi KM, Cho D

Cis-AB and B(A) alleles encode an ABO enzyme with dual A and B glycosyltransferase activity. Although globally rare, the cis-AB phenotype is found relatively often in Korean, Japanese, and Chinese...
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A machine-learning expert-supporting system for diagnosis prediction of lymphoid neoplasms using a probabilistic decision-tree algorithm and immunohistochemistry profile database

Chong Y, Lee JY, Kim Y, Choi J, Yu H, Park G, Cho MY, Thakur N

Background: Immunohistochemistry (IHC) has played an essential role in the diagnosis of hematolymphoid neoplasms. However, IHC interpretations can be challenging in daily practice, and exponentially expanding volumes of IHC data...
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A Case of Partial D Type VI-3 Confirmed by RHD Genotyping

Lee JK, Yu H, Chung YN, Bae JC, Cho D

Weak D and partial D result in quantitative and qualitative changes in RhD protein expression respectively. It is difficult to discriminate weak D from partial D by serological tests alone....
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Accuracy and clinical feasibility of 3D‑myocardial thickness map measured by cardiac computed tomogram

Kwon O, Lee J, Lim S, Park J, Han H, Yang S, Hwang I, Yu H, Kim T, Uhm J, Joung B, Lee M, Pak H

Background: Although myocardial thickness is an important variable for therapeutic catheter ablation of cardiac arrhythmias, quantification of wall thickness has been overlooked. We developed a software (AMBER) that measures 3D-myocardial...
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Weak D Type 102 Found in a Family Study: The First Case in Korea

Lee B, Chung YN, Yu H, Kim TY, Choi KM, Cho D

Weak D type 102 allele (RHD*01W.102) carrying a missense variant (c.73A>T, p.Ile25Phe) in exon 1 of the RHD has not been reported in Koreans to date. This is the first...
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First Korean Case of Partial D DBS-1

Choi S, Yu H, Cho D

No abstract available.
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Parental Factors Associated with Smartphone Overuse in Preschoolers: A Systematic Review and Meta-Analysis

Lee G, Kim S, Yu H

Purpose: This study aimed to identify parental factors associated with smartphone overuse in preschoolers. Methods: A systematic reviewwas conducted according to PRISMA guidelines. Relevant studies published in peer-reviewed journals from...
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Clinical and genetic relationships between the QTc interval and risk of a stroke among atrial fibrillation patients undergoing catheter ablation

Hong M, Chun K, Hwang I, Yu H, Kim T, Uhm J, Joung B, Lee M, Pak H

Background and objectives: A prolonged QTc interval is associated with an increased risk of a stroke or atrial fibrillation (AF). However, its direct causal relationship with AF associated a stroke...
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Assessment of the Predictive Role of Serum Lipid Profiles in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy

Qu F, Chen R, Peng Y, Ye Y, Tang Z, Wang Y, Zong B, Yu H, Liu S

Purpose: Effective predictors of the response to neoadjuvant chemotherapy (NAC) are still insufficient. This study aimed to investigate the predictive value of serum lipid profiles for the response to NAC...
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Advice on Standardized Diagnosis and Treatment for Spinal Diseases during the Coronavirus Disease 2019 Pandemic

Zou J, Yu H, Song D, Niu J, Yang H

Coronavirus disease 2019 (COVID-19) outbreak started in December 2019 that caused difficulties for clinical work. Practical work experience in our spinal outpatient and emergency department during the COVID-19 pandemic is...
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Ageism between Medical and Preliminary Medical Persons in Korea

Lee J, Yu H, Cho HH, Kim M, Yang S

Background: We tried to analyse the trends in ageism among health care providers and medical students in the Republic of Korea. Methods: We used the Fraboni Scale of Ageism (FSA),...
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