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Selective inhibition of V600E-mutant BRAF gene induces apoptosis in thyroid carcinoma cell lines

Park KS, Saindane M, Yang EY, Jin T, Rallabandi HR, Heil A, Nam SE, Yoo YB, Yang JH, Kim JB, Park SY, Park WS, Youn YK

Purpose: Papillary thyroid cancer (PTC) has a high incidence of BRAF V600E mutation. The purpose of this study was to evaluate the potential relationship between thyroiditis and BRAF ...
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Concordance of Programmed DeathLigand 1 Expression between SP142 and 22C3/SP263 Assays in Triple-Negative Breast Cancer

Lee SE, Park HY, Lim SD, Han HS, Yoo YB, Kim WS

Purpose: Triple-negative breast cancer (TNBC) represents a major clinical challenge due to its aggressive and metastatic behavior and the lack of available targeted therapies. Therefore, therapeutic strategies are needed to...
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Postthyroidectomy obesity in a Korean population: does the extent of surgery matter?

Park MY, Nam SE, Park KS, Saindane M, Yoo YB, Yang JH, Ahn AL, Choi JK, Park WS

PURPOSE: The purpose of this study was to investigate the prevalence of postthyroidectomy obesity, and the relationship between the extent of thyroidectomy and obesity. METHODS: A survey conducted at an outpatient...
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Selective B-RAF V600E Inhibitor PLX4032 Inhibits the Growth of Breast Cancer Cell Lines through Cell Cycle Arrest

Yang EY, Park MY, Jung SM, Nam SE, Kwon JO, Yoo YB, Yang JH, Park KS

PURPOSE: Breast cancer is the most common invasive cancer and the second common cause of death among women worldwide. Many researchers have focused on the effective treatment of advanced breast...
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Dietary Changes After Breast Cancer Diagnosis: Associations with Physical Activity, Anthropometry, and Health-related Quality of life Among Korean Breast Cancer Survivors

Song S, Youn HJ, Jung SY, Lee E, Kim Z, Cho J, Yoo YB, Moon HG, Noh DY, Lee JE

OBJECTIVES: We aimed to examine levels of physical activity, anthropometric features, and health-related quality of life (HRQoL) among Korean breast cancer survivors who reported changes in their diet after diagnosis. METHODS:...
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Mu-Opioid Receptor Polymorphisms and Breast Cancer in a Korean Female Adult Population: A Retrospective Study

Oh CS, Lee SH, Yoo YB, Yang JH, Kim SH

Distribution of A118G single nucleotide polymorphism (SNP) in the mu-opioid receptor 1 gene (OPRM1) differs with ethnicity. We assessed the distribution of this SNP in Korean women with breast cancer...
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Forkhead Transcription Factor FOXO1 Inhibits Angiogenesis in Gastric Cancer in Relation to SIRT1

Kim SY, Ko YS, Park J, Choi Y, Park JW, Kim Y, Pyo JS, Yoo YB, Lee JS, Lee BL

PURPOSE: We previously reported that forkhead transcription factors of the O class 1 (FOXO1) expression in gastric cancer (GC) was associated with angiogenesis-related molecules. However, there is little experimental evidence...
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Tissue transglutaminase-interleukin-6 axis facilitates peritoneal tumor spreading and metastasis of human ovarian cancer cells

Oh K, Moon HG, Lee DS, Yoo YB

Inflammation has recently been implicated in cancer formation and progression. As tissue transglutaminase (TG2) has been associated with both inflammatory signaling and tumor cell behavior, we propose that TG2 may...
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Seroprevalence of Trichinella sp. in Wild Boars (Sus scrofa) from Yanggu-gun, Gangwon-do, Korea

Lee HJ, Chung OS, Kim JL, Lee SH, Yoo YB, Seo M

A total 7 outbreaks of trichinellosis have occurred in Korea, mostly as a result of consumption of raw wild boar (Sus scrofa) meat. Since only 1 serological survey on wild...
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A comparative analysis of endoscopic thyroidectomy versus conventional thyroidectomy in clinically lymph node negative thyroid cancer

Cho MJ, Park KS, Cho MJ, Yoo YB, Yang JH

PURPOSE: Differentiated thyroid cancer has a good prognosis and high incidence in young women. Since endoscopic techniques were first recorded in 1996, surgical indications of endoscopic thyroidectomy have broadened. Therefore,...
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Effects of combination therapy of docetaxel with selenium on the human breast cancer cell lines MDA-MB-231 and MCF-7

Park SO, Yoo YB, Kim YH, Baek KJ, Yang JH, Choi PC, Lee JH, Lee KR, Park KS

PURPOSE: The anticancer property and cytoprotective role of selenium in chemotherapy have been reported. However, the combination effects of selenium on chemotherapy for advanced breast cancer have not yet been...
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Axillary sparganosis which was misunderstood lymph node metastasis during neoadjuvant chemotheraphy in a breast cancer patient

Lee EK, Yoo YB

Sparganosis of the breast is an uncommon disease, but should be considered in the differential diagnosis of unusual and suspicious breast masses. A history of ingesting contaminated water and direct...
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Proper Application of Cyber Lecture on Neuroanatomy for Medical Students

Yoo YB, Yang HM, Park JH, Lee YI

Recent development of cyber lecture system has greatly influenced on the medical education especially on anatomy related subjects. Furthermore, the technology associated to the cyber lecture system is now widely...
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Imaging Mass Spectrometry in Papillary Thyroid Carcinoma for the Identification and Validation of Biomarker Proteins

Min KW, Bang JY, Kim KP, Kim WS, Lee SH, Shanta SR, Lee JH, Hong JH, Lim SD, Yoo YB, Na CH

Direct tissue imaging mass spectrometry (IMS) by matrix-assisted laser desorption ionization and time-of-flight (MALDI-TOF) mass spectrometry has become increasingly important in biology and medicine, because this technology can detect the...
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Overproduction of Laccase by the White-Rot Fungus Pleurotus ostreatus Using Apple Pomace as Inducer

Park YJ, Yoon DE, Kim HI, Kwon OC, Yoo YB, Kong WS, Lee CS

  • KMID: 2312745
  • Mycobiology.
  • 2014 Jun;42(2):193-197.
Laccase activity of Pleurotus ostreatus is significantly increased by the addition of apple pomace. Among various conditions, the best concentration of apple pomace and cultivation time for the production of...
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A Comparative Analysis of Endoscopic Versus Conventional Open Thyroidectomy in the Treatment of Papillary Thyroid Cancer According to Preoperative Risk Stratification

Kang BJ, Park KS, Seo SY, Kim KY, Cho MJ, Yoo YB, Yang JH

PURPOSE: It is well known that papillary thyroid cancer (PTC) has a good prognosis and high incidence in young women. The objective of the study was to review our criteria...
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Simultaneous Chest Wall Reconstruction after Sternectomy and Modified Radical Mastectomy in Locally Advanced Breast Cancer with Solitary Sternal Metastasis

Kang HJ, Lee SA, Park KS, Yang JH, Yoo YB

Bone is the most common metastatic organ in patients with breast cancer. The most significant clinical symptom of bone metastasis is pain which reduces quality of life in cancer patients....
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Anticancer and Immunopotentiating Activities of Crude Polysaccharides from Pleurotus nebrodensis on Mouse Sarcoma 180

Cha YJ, Alam N, Lee JS, Lee KR, Shim MJ, Lee MW, Kim HY, Shin PG, Cheong JC, Yoo YB, Lee TS

Pleurotus nebrodensis is an edible and commercially available mushroom in Korea. This study was conducted in order to evaluate the anticancer and immunopotentiating activities of crude polysaccharides, extracted in methanol,...
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Immunomodulating and Antitumor Activities of Panellus serotinus Polysaccharides

Kim JH, Lee JS, Lee KR, Shim MJ, Lee MW, Shin PG, Cheong JC, Yoo YB, Lee TS

  • KMID: 2312671
  • Mycobiology.
  • 2012 Sep;40(3):181-188.
This study was initiated in order to investigate the anticancer and immunomodulating activities of crude polysaccharides extracted in methanol, neutral saline, and hot water (hereinafter referred to as Fr. MeOH,...
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Taxonomy of Ganoderma lucidum from Korea Based on rDNA and Partial beta-Tubulin Gene Sequence Analysis

Park YJ, Kwon OC, Son ES, Yoon DE, Han W, Yoo YB, Lee CS

  • KMID: 2408216
  • Mycobiology.
  • 2012 Mar;40(1):71-75.
In the present study, a phylogenetic analysis was undertaken based on the internal transcribed spacer (ITS) rDNA and partial beta-tubulin gene sequence of the Ganoderma species. The size of the...
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