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Lactate: a multifunctional signaling molecule

Lee TY

Since its discovery in 1780, lactate has long been misunderstood as a waste by-product of anaerobic glycolysis with multiple deleterious effects. Owing to the lactate shuttle concept introduced in the...
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Hemophagocytic lymphohistiocytosis with recurrent Kikuchi-Fujimoto disease

Lee SM, Lim YT, Jang KM, Gu MJ, Lee JH, Lee JM

Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a self-limiting lymphadenitis. It is a benign disease mainly characterized by high fever, lymph node swelling, and leukopenia. Hemophagocytic lymphohistiocytosis...
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Psychiatric understanding and treatment of patients with amputations

Jo SH, Kang SH, Seo WS, Koo BH, Kim HG, Yun SH

Amputation changes the lives of patients and their families. Consequently, the patient must adapt to altered body function and image. During this adaptation process, psychological problems, such as depression, anxiety,...
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Successful laparoscopic surgery of accessory cavitated uterine mass in young women with severe dysmenorrhea

Park JC, Kim DJ

Accessory cavitated uterine mass (ACUM) is a rare and unique condition seen in young women. We report cases of ACUMs in two patients, a 14-year-old girl and a 25-year-old woman,...
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Clinical effectiveness of omental transposition in facilitating perineal wound healing after abdominoperineal resection: a systematic review

Kim S, Kang SI, Kim S, Kim JH

Background: Omental transposition has been used to facilitate perineal wound healing in patients undergoing abdominoperineal resection (APR). However, there is no high-level evidence supporting the effectiveness of omental transposition in...
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Breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL)

Lee JH

Breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL) is a rare T-cell non-Hodgkin lymphoma characterized as CD30 positive and anaplastic lymphoma kinase (ALK) negative. In 2016, the World Health Organization declared BIA-ALCL...
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Metachronous extranodal natural killer/T-cell lymphoma of nasal type and primary testicular lymphoma

Maeng YI, Lee SJ

We report a rare case of metachronous lymphoma with two distinct cell lineages in a 75-year-old man. The patient complained about having nasal obstruction for 2 years and extranodal natural...
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A retrospective analysis of etiology and outcomes of hemophagocytic lymphohistiocytosis in children and adults

Kwak A, Jung N, Shim YJ, Kim HS, Lim HJ, Lee JM, Heo MH, Do YR

Background: Hemophagocytic lymphohistiocytosis (HLH) is a rare but severe, life-threatening inflammatory condition if untreated. We aimed to investigate the etiologies, outcomes, and risk factors for death in children and adults...
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The diagnosis of an imperforate anus in female fetuses

Kim HM, Cha HH, Kim JI, Seong WJ, Park SH, Kim MJ

Imperforate anus is an anomaly caused by a defect in the development of the hindgut during early pregnancy. It is a relatively common congenital malformation and is more common in...
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Successful treatment with vedolizumab in an adolescent with Crohn disease who had developed active pulmonary tuberculosis while receiving infliximab

Choi S, Choi BS, Choe BH, Kang B

Vedolizumab (VDZ) has been approved for the treatment of inflammatory bowel diseases (IBDs) in patients aged ≥18 years. We report a case of a pediatric patient with Crohn disease (CD)...
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Personal experience with microvascular decompression and partial sensory rhizotomy for trigeminal neuralgia

Lee JH, Lee JM, Choi CH

Background: Trigeminal neuralgia (TN) is a severe, paroxysmal pain in the distribution of the fifth cranial nerve. Microvascular decompression (MVD) is the most widely used surgical treatment for TN. We...
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Sciatic nerve neurolymphomatosis as the initial presentation of primary diffuse large B-cell lymphoma: a rare cause of leg weakness

Kim KT, Kim SI, Do YR, Jung HR, Cho JH

Neurolymphomatosis (NL) is defined as the involvement of the peripheral nervous system in lymphocytic invasion. It is a very rare form of lymphoma that may occur as an initial presentation...
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Significance of albumin to globulin ratio as a predictor of febrile urinary tract infection after ureteroscopic lithotripsy

Yi SY, Park DJ, Min K, Chung JW, Ha YS, Kim BS, Kim HT, Kim TH, Yoo ES

Background: We aimed to analyze the effectiveness of albumin to globulin ratio (AGR) in predicting postoperative febrile urinary tract infection (fUTI) after ureteroscopic lithotripsy (URS) and retrograde intrarenal surgery (RIRS). Methods:...
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