- Effect of FTY-720 on Pulmonary Fibrosis in Mice via the TGF-β1 Signaling Pathway and Autophagy
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Jin Y, Liu W, Gao G, Song Y, Liu H, Li L, Zhou J, Yan G, Cui H
- KMID: 2544066
- Biomol Ther.
- 2023 Jul;31(4):434-445.
- doi: 10.4062/biomolther.2022.123
We investigated whether FTY-720 might have an effect on bleomycin-induced pulmonary fibrosis through inhibiting TGF-β1 pathway, and up-regulating autophagy. The pulmonary fibrosis was induced by bleomycin. FTY-720 (1 mg/kg) drug... -
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- Evaluation of the Luminex ARIES HSV 1&2 Assay and Comparison with the FTD Neuro 9 and In-house Real-Time PCR Assays for Detecting Herpes Simplex Viruses
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Lee CK, Chai CN, Capinpin S, Ang A, Ng SY, Lee PL, Ng CW, Yan G, Lee HK, Chiu LL, Jureen R, Yan B, Loh TP
- KMID: 2434733
- Ann Lab Med.
- 2018 Sep;38(5):440-445.
- doi: 10.3343/alm.2018.38.5.440
BACKGROUND: Human herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are responsible for a plethora of human diseases, of which cutaneous and mucocutaneous infections are the most prevalent.... -
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- Range of Varicella Zoster Co-Infections with COVID-19, Singapore
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Loh J, Tham SM, Tambyah PA, Yan G, Lee CK, Chai LYA
- KMID: 2517471
- Infect Chemother.
- 2021 Jun;53(2):391-394.
- doi: 10.3947/ic.2020.0154
There have been recent descriptions of the novel coronavirus disease 2019 (COVID-19) presenting as ‘varicella-like exanthem’. We report three cases of patients with VaricellaZoster Virus (VZV) and COVID-19 co-infections, presenting... -
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- Pharmacokinetics and Bio-distribution of New Gd-complexes of DTPA-bis (amide) (L3) in a Rat Model
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Yan G, Wu R, Chang Y, Kang D
- KMID: 2144327
- J Korean Soc Magn Reson Med.
- 2013 Dec;17(4):259-266.
- doi: 10.13104/jksmrm.2013.17.4.259
PURPOSE: To investigate the blood pharmacokinetics and bio-distribution of DTPA-bis-amide (L3) Gd(III) complexes. MATERIALS AND METHODS: The pharmacokinetics and bio-distribution of Gd (L3)(H2O).nH2O were investigated in Sprague-Dawley rats after intravenous administration... -
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- Beneficial effects of andrographolide in a rat model of autoimmune myocarditis and its effects on PI3K/Akt pathway
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Zhang Q, Hu LQ, Li HQ, Wu J, Bian NN, Yan G
- KMID: 2438084
- Korean J Physiol Pharmacol.
- 2019 Mar;23(2):103-111.
- doi: 10.4196/kjpp.2019.23.2.103
The study is to investigate effects of andrographolide on experimental autoimmune myocarditis (EAM). Lewis rats were immunized on day 0 with porcine cardiac myosin to establish EAM. The EAM rats... -
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