- Quantification of Nerve Viscosity Using Shear Wave Dispersion Imaging in Diabetic Rats: A Novel Technique for Evaluating Diabetic Neuropathy
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Liu F, Li D, Xin Y, Liu F, Li W, Zhu J
- KMID: 2525220
- Korean J Radiol.
- 2022 Feb;23(2):237-245.
- doi: 10.3348/kjr.2021.0603
Objective: Viscoelasticity is an essential feature of nerves, although little is known about their viscous properties. The discovery of shear wave dispersion (SWD) imaging has presented a new approach for... -
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- TM6SF2 E167K variant decreases PNPLA3-mediated PUFA transfer to promote hepatic steatosis and injury in MASLD
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Sun B, Ding X, Tan J, Zhang J, Chu X, Zhang S, Liu S, Zhao Z, Xuan S, Xin Y, Zhuang L
- KMID: 2560090
- Clin Mol Hepatol.
- 2024 Oct;30(4):863-882.
- doi: 10.3350/cmh.2024.0268
Backgrounds/Aims: Transmembrane 6 superfamily member 2 (TM6SF2) E167K variant is closely associated with the occurrence and development of metabolic dysfunction-associated steatotic liver disease (MASLD). However, the role and mechanism of... -
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- Contributions of HO-1-Dependent MAPK to Regulating Intestinal Barrier Disruption
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Zhang Z, Zhang Q, Li F, Xin Y, Duan Z
- KMID: 2513485
- Biomol Ther.
- 2021 Mar;29(2):175-183.
- doi: 10.4062/biomolther.2020.131
The mitogen-activated protein kinase (MAPK) pathway controls intestinal epithelial barrier permeability by regulating tight junctions (TJs) and epithelial cells damage. Heme oxygenase-1 (HO-1) and carbon monoxide (CO) protect the intestinal... -
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- Protective Role of Fucoidan in Cerebral Ischemia-Reperfusion Injury through Inhibition of MAPK Signaling Pathway
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Che N, Ma Y, Xin Y
- KMID: 2378805
- Biomol Ther.
- 2017 May;25(3):272-278.
- doi: 10.4062/biomolther.2016.098
Fucoidan has been reported to exhibit various beneficial activities ranging from to antivirus and anticancer properties. However, little information is available about the effects of fucoidan on cerebral ischemia-reperfusion injury... -
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- Trastuzumab Combined with Irinotecan in Patients with HER2-Positive Metastatic Colorectal Cancer: A Phase II Single-Arm Study and Exploratory Biomarker Analysis
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Xu T, Wang X, Xin Y, Wang Z, Gong J, Zhang X, Li Y, Ji C, Sun Y, Zhao F, Huang D, Bai Y, Li J, Shen L
- KMID: 2541249
- Cancer Res Treat.
- 2023 Apr;55(2):626-635.
- doi: 10.4143/crt.2022.1058
Purpose The human epidermal growth factor receptor 2 (HER2) is an established therapeutic target for various kinds of solid tumors. HER2 amplification occurs in approximately 1% to 6% of colorectal... -
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- Tafamidis, a Noninvasive Therapy for Delaying Transthyretin Familial Amyloid Polyneuropathy: Systematic Review and Meta-Analysis
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Zhao Y, Xin Y, Song Z, He Z, Hu W
- KMID: 2451153
- J Clin Neurol.
- 2019 Jan;15(1):108-115.
- doi: 10.3988/jcn.2019.15.1.108
BACKGROUND AND PURPOSE: Tafamidis functions to delay the loss of function in transthyretin familial amyloid polyneuropathy (TTR-FAP), which is a rare inherited amyloidosis with progressive sensorimotor and autonomic polyneuropathy. This... -
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