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A Two-DNA Methylation Signature to Improve Prognosis Prediction of Clear Cell Renal Cell Carcinoma

Shi S, Ye S, Wu X, Xu M, Zhuo R, Liao Q, Xi Y

PURPOSE: Effective biomarkers and models are needed to improve the prognostic prospects of clear cell renal cell carcinoma (ccRCC). The purpose of this work was to identify DNA methylation biomarkers...
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An Intratracheal Challenge Murine Model of Asthma: Can Bronchial Inflammation Affect the Nose?

Xie J, Xi Y, Zhang Q, Chen G, Wei L, Lai K, Zhong N

PURPOSE: Extensive data support the influence of the upper airway on lower airway inflammation and pathophysiology in allergic disease. However, few studies have focused on allergic inflammation in the nose...
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Monitoring Response to Neoadjuvant Chemotherapy of Primary Osteosarcoma Using Diffusion Kurtosis Magnetic Resonance Imaging: Initial Findings

Liu C, Xi Y, Li M, Jiao Q, Zhang H, Yang Q, Yao W

OBJECTIVE: To determine whether diffusion kurtosis imaging (DKI) is effective in monitoring tumor response to neoadjuvant chemotherapy in patients with osteosarcoma. MATERIALS AND METHODS: Twenty-nine osteosarcoma patients (20 men and 9...
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Integrin β1 in Adipose-Derived Stem Cells Accelerates Wound Healing via Activating PI3K/AKT Pathway

Wang Q, Zhang N, Hu L, Xi Y, Mi W, Ma Y

Background: This study aims to investigate the effect of integrin β1 on wound healing induced by adipose-derived stem cells (ADSCs), as well as the corresponding mechanism. Methods: Integrin β1 was overexpressed...
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¹²⁵I Seed Permanent Implantation as a Palliative Treatment for Stage III and IV Hypopharyngeal Carcinoma

Li L, Yang J, Li X, Wang X, Ren Y, Fei J, Xi Y, Sun R, Ma J

OBJECTIVES: The aim of this study was to investigate the feasibility and safety of percutaneous ¹²⁵I seed permanent implantation for advanced hypopharyngeal carcinoma from toxicity, tumor response, and short-term outcome. METHODS:...
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Role of soy lecithin combined with soy isoflavone on cerebral blood flow in rats of cognitive impairment and the primary screening of its optimum combination

Li H, Wang X, Li X, Zhou X, Wang X, Li T, Xiao R, Xi Y

BACKGROUND/OBJECTIVES: Soy isoflavone (SIF) and soy lecithin (SL) have beneficial effects on many chronic diseases, including neurodegenerative diseases. Regretfully, there is little evidence to show the combined effects of these...
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Independent Correlation of the C1–2 Cobb Angle With Patient-Reported Outcomes After Correcting Chronic Atlantoaxial Instability

Pan Z, Xi Y, Huang W, Kim KN, Yi S, Shin DA, Huang K, Chen Y, Huang Z, He D, Ha Y

OBJECTIVE: To investigate three-planar radiographic results and patient-reported outcomes (PROs) after correcting chronic atlantoaxial instability (AAI) by translaminar screw (TLS) and pedicle screw (PS) fixation, and to explore the potential...
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