- The Inhibitory Effect of Quercetin-3-O-beta-D-Glucuronopyranoside on Gastritis and Reflux Esophagitis in Rats
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Min YS, Lee SE, Hong ST, Kim HS, Choi BC, Sim SS, Whang WK, Sohn UD
- KMID: 2071684
- Korean J Physiol Pharmacol.
- 2009 Aug;13(4):295-300.
- doi: 10.4196/kjpp.2009.13.4.295
It was evaluated the inhibitory action of quercetin-3-O-beta-D-glucuronopyranoside (QGC) on reflux esophagitis and gastritis in rats. QGC was isolated from the herba of Rumex Aquaticus. Reflux esophagitis or gastritis was... -
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- Scopoletin from Cirsium setidens Increases Melanin Synthesis via CREB Phosphorylation in B16F10 Cells
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Ahn MJ, Hur SJ, Kim EH, Lee SH, Shin JS, Kim MK, Uchizono J, Whang WK, Kim DS
- KMID: 2285524
- Korean J Physiol Pharmacol.
- 2014 Aug;18(4):307-311.
- doi: 10.4196/kjpp.2014.18.4.307
In this study, we isolated scopoletin from Cirsium setidens Nakai (Compositae) and tested its effects on melanogenesis. Scopoletin was not toxic to cells at concentrations less than 50 microM and... -
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- Acute Toxicity and General Pharmacological Action of QGC EXT
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Lee JM, Im WJ, Nam YJ, Oh KH, Lim JC, Whang WK, Sohn UD
- KMID: 2285440
- Korean J Physiol Pharmacol.
- 2012 Feb;16(1):49-57.
- doi: 10.4196/kjpp.2012.16.1.49
It has been shown that QGC isolated and purified from Rumecis folium found protective effects of gastritis and esophagitis which EXT is an ethanol extract of it. We examined acute... -
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- The Protective Effect of Quercetin-3-O-beta-D-Glucuronopyranoside on Ethanol-induced Damage in Cultured Feline Esophageal Epithelial Cells
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Cho JH, Park SY, Lee HS, Whang WK, Sohn UD
- KMID: 2285417
- Korean J Physiol Pharmacol.
- 2011 Dec;15(6):319-326.
- doi: 10.4196/kjpp.2011.15.6.319
Quercetin-3-O-beta-D-glucuronopyranoside (QGC) is a flavonoid glucoside extracted from Rumex Aquaticus Herba. We aimed to explore its protective effect against ethanol-induced cell damage and the mechanism involved in the effect in... -
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- Effect of ECQ on Iodoacetamide-Induced Chronic Gastritis in Rats
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Lee SE, Song HJ, Park SY, Nam Y, Min CH, Lee DY, Jeong JY, Ha HS, Kim HJ, Whang WK, Jeong JH, Kim IK, Kim HR, Min YS, Sohn UD
- KMID: 1500244
- Korean J Physiol Pharmacol.
- 2013 Oct;17(5):469-477.
- doi: 10.4196/kjpp.2013.17.5.469
This study investigated effect of extract containing quercetin-3-O-beta-D-glucuronopyranoside from Rumex Aquaticus Herba (ECQ) against chronic gastritis in rats. To produce chronic gastritis, the animals received a daily intra-gastric administration of... -
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- Methyl gallate and chemicals structurally related tomethyl gallate protect human umbilical vein endothelial cells from oxidative stress
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Whang WK, Park HS, Ham IH, Oh M, Namkoong H, Kim HK, Hwang DW, Hur SY, Kim TE, Park YG, Kim JR, Kim JW
- KMID: 1093469
- Exp Mol Med.
- 2005 Aug;37(4):343-352.
Methyl gallate (meGAL) is known as one of major antioxidants. To investigate whether meGAL protects human cells from oxidative stress, meGAL extracted from Korean medicinal plant, Cercis chinensis leaves, was... -
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- Natural compounds, fraxin and chemicals structurally related to fraxin protect cells from oxidative stress
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Whang WK, Park HS, Ham I, Oh M, Namkoong H, Kim HK, Hwang DW, Hur SY, Kim TE, Park YG, Kim JR, Kim JW
- KMID: 1089453
- Exp Mol Med.
- 2005 Oct;37(5):436-446.
Coumarins comprise a group of natural phenolic compounds found in a variety of plant sources. In view of the established low toxicity, relative cheapness, presence in the diet and occurrence... -
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