- Golimumab Therapy in Ulcerative Colitis
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Moon W
- KMID: 2383543
- Korean J Gastroenterol.
- 2016 Feb;67(2):64-73.
- doi: 10.4166/kjg.2016.67.2.64
Ulcerative colitis is a chronic inflammatory condition of the colon, characterized by diffuse mucosal inflammation and blood-mixed diarrhea. The main treatment has been 5-aminosalicylic acid, steroid, thiopurine, and anti-tumor necrosis... -
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- One target, different effects: a comparison of distinct therapeutic antibodies against the same targets
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Shim H
- KMID: 1123366
- Exp Mol Med.
- 2011 Oct;43(10):539-549.
- doi: 10.3858/emm.2011.43.10.063
To date, more than 30 antibodies have been approved worldwide for therapeutic use. While the monoclonal antibody market is rapidly growing, the clinical use of therapeutic antibodies is mostly limited... -
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- Pro- and anti-inflammatory cytokine expression and histopathological characteristics in canine brain with traumatic brain injury
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Yu CH, Yhee JY, Kim JH, Im KS, Kim NH, Jung DI, Lee HC, Chon SK, Sur JH
- KMID: 1067405
- J Vet Sci.
- 2011 Sep;12(3):299-301.
- doi: 10.4142/jvs.2011.12.3.299
We analyzed the expression level and cellular localization of pro- and anti-inflammatory cytokines and histopathologically characterized canine traumatic brain injury (TBI). Canine TBI brains revealed subarachnoid and cerebral cortical hemorrhage,... -
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- A Case of Crohn's Disease Showing Favorable Response to Induction and Maintenance Therapy with Methotrexate after Failure of Anti-tumor Necrosis Factor Therapy
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Choi J, Yun GW, Park YM, Kim JH, Youn YH, Park H, Park JJ
- KMID: 2373347
- Korean J Gastroenterol.
- 2015 Oct;66(4):231-236.
- doi: 10.4166/kjg.2015.66.4.231
Thanks to the introduction of immumomodulators and biologics, therapeutic approaches in Crohn's disease have changed significantly during the past decade. Although new biologic therapy has dramatically improved the treatment of... -
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- Extracellular HIV-1 Tat up-regulates expression of matrix metalloproteinase-9 via a MAPK-NF-kappaB dependent pathway in human astrocytes
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Ju SM, Song HY, Lee JA, Lee SJ, Choi SY, Park J
- KMID: 1109431
- Exp Mol Med.
- 2009 Feb;41(2):86-93.
- doi: 10.3858/emm.2009.41.2.011
The infiltration of monocytes into the CNS represents one of the early steps to inflammatory events in AIDS-related encephalitis and dementia. Increased activity of selected matrix metalloproteinases (MMPs) such as... -
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- Changing Paradigm in the Management of Inflammatory Bowel Disease
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Jang BI
- KMID: 2373222
- Korean J Gastroenterol.
- 2015 May;65(5):268-272.
- doi: 10.4166/kjg.2015.65.5.268
Inflammatory bowel disease (IBD) is a chronic progressive idiopathic inflammatory disorder that involves the digestive tract from the mouth to the anus. Over the past decades, many therapeutic strategies have... -
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- MiR-155 modulates the inflammatory phenotype of intestinal myofibroblasts by targeting SOCS1 in ulcerative colitis
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Pathak S, Grillo AR, Scarpa M, Brun P, D'Inca R, Nai L, Banerjee A, Cavallo D, Barzon L, Palu G, Sturniolo , Buda A, Castagliuolo I
- KMID: 2155656
- Exp Mol Med.
- 2015 May;47(5):e164.
- doi: 10.1038/emm.2015.21
Abnormal levels of microRNA (miR)-155, which regulate inflammation and immune responses, have been demonstrated in the colonic mucosa of patients with inflammatory bowel diseases (IBD), although its role in disease... -
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- Pathogenesis and Treatment of Intestinal Behcet's Disease
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Lee CK, Kim HJ
- KMID: 782880
- Korean J Gastroenterol.
- 2007 Jul;50(1):3-8.
Intestinal Behcet's disease (BD) refers to colonic ulcerative lesions documented by objective measures in patients with BD. Although the causes of intestinal BD are unknown, genetic, environmental, and immunological factors... -
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