- The colchicine derivative CT20126 shows a novel microtubule-modulating activity with apoptosis
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Kim SK, Cho SM, Kim H, Seok H, Kim SO, Kwon TK, Chang JS
- KMID: 2154238
- Exp Mol Med.
- 2013 Apr;45(4):e19.
New colchicine analogs have been synthesized with the aim of developing stronger potential anticancer activities. Among the analogs, CT20126 has been previously reported to show immunosuppressive activities. Here, we report... -
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- Serial Morphological Changes of Side-Branch Ostium after Paclitaxel-Coated Balloon Treatment of De Novo Coronary Lesions of Main Vessels
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Her AY, Ann SH, Singh GB, Kim YH, Okamura T, Garg S, Koo BK, Shin ES
- KMID: 2374078
- Yonsei Med J.
- 2016 May;57(3):606-613.
- doi: 10.3349/ymj.2016.57.3.606
PURPOSE: The effects on the side-branch (SB) ostium, following paclitaxel-coated balloon (PCB) treatment of de novo coronary lesions of main vessels have not been previously investigated. This study was aimed... -
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- Intestinal Amyloidosis with Intractable Diarrhea and Intestinal Pseudo-obstruction
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Kim YJ, Kim HS, Park SY, Park SW, Choi YD, Park CH, Choi SK, Rew JS
- KMID: 1389726
- Korean J Gastroenterol.
- 2012 Sep;60(3):172-176.
- doi: 10.4166/kjg.2012.60.3.172
We report herein a case of intestinal amyloidosis with grave prognosis that caused intractable diarrhea and intestinal pseudo-obstruction, alternately in spite of intensive conservative treatment. A 44-year-old woman was admitted... -
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- Disruption of Microtubules Sensitizes the DNA Damage-induced Apoptosis Through Inhibiting Nuclear Factor kappaB (NF-kappaB) DNA-binding Activity
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Lee H, Jeon J, Ryu YS, Jeong JE, Shin S, Zhang T, Kang SW, Hong JH, Hur GM
- KMID: 1779226
- J Korean Med Sci.
- 2010 Nov;25(11):1574-1581.
- doi: 10.3346/jkms.2010.25.11.1574
The massive reorganization of microtubule network involves in transcriptional regulation of several genes by controlling transcriptional factor, nuclear factor-kappa B (NF-kappaB) activity. The exact molecular mechanism by which microtubule rearrangement... -
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