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A Case of Midazolam Anaphylaxis

Shin JG, Hwang JH, Lee BS, Park HJ, Lee SH, Lee JN, Han DH, Kim JH

Midazolam is a type of anesthetic agent frequently used for conscious sedation during a variety of medical procedures. Anaphylactic reactions to midazolam are rarely reported. However, we observed a case...
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Usefulness of Mast Cell Tryptase Analysis for Postmortem Diagnosis of Anaphylactic Shock

Park JP, Koo BY, Lee NW

Anaphylactic shock (AS) is a systemic and life-threatening type I hypersensitivity reaction and is often encountered at an autopsy. However, postmortem diagnosis of AS can be difficult due to non-specific...
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Elevated level of serum tryptase in a patient with exercise-inuced anaphylaxis

Ye YM, Lim SG, Suh YJ, Choi JH, Suh CH, Nahm DH, Park HS

  • KMID: 2285829
  • J Asthma Allergy Clin Immunol.
  • 2004 Mar;24(1):152-155.
Exercise-induced anaphylaxis (EIA) is a medical emergency in that it derives from a physical allergy. We reported a case of food-independent EIA based on history and laboratory data. A 40-year-old...
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Usefulness of Serum Mast Cell Tryptase Analysis in Postmortem Diagnosis of Anaphylactic Shock

Park JP, Choi M, Kim SH, Jang SJ, Kim HJ

Anaphylactic deaths are frequently observed at autopsies. Since death associated with medical practice has become social concern, the identification of anaphylactic shock is an important part of forensic medicine. However,...
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Expression of Mast Cell Tryptase in the Chronic Otitis Media with Effusion

Jang CH, Kim YH, Jung JK

  • KMID: 2275861
  • Korean J Otolaryngol-Head Neck Surg.
  • 2002 Feb;45(2):111-113.
BACKGROUND AND OBJECTIVES: Mast cells are localized in the middle ear and Eustachian tube. They play a prominent role in the inflammatory and allergic conditions. The purpose of this study...
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Tryptase and Protease-Activated Receptor 2 Expression Levels in Irritable Bowel Syndrome

Liang WJ, Zhang G, Luo HS, Liang LX, Huang D, Zhang FC

BACKGROUND/AIMS: Previous studies have revealed that mast cells (MCs) may activate the protease-activated receptors and release of neuropeptides involved in the pathogenesis of irritable bowel syndrome (IBS). The levels of...
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Anaphylaxis following atropine administration during general anesthesia: a case report

Choi J, Kim H, Jeon YS, Hong DM

Anaphylaxis is an acute, potentially lethal, multisystem syndrome resulting from the sudden release of mast-cell- and basophile-derived mediators into the circulation. Common manifestations of anaphylactic reactions include urticaria, angioedema, nausea,...
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In Vitro Culture of Mast Cells from Human Umbilical Cord Blood Cells

Ahn KM, Lee SI

  • KMID: 1994352
  • Pediatr Allergy Respir Dis.
  • 1999 Dec;9(4):396-405.
PURPOSE: The purpose of this study is to induce the differentiation of mast cells from human umbilical cord blood. METHODS: Mononuclear cells and CD34+ cells were obtained from cord blood...
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Anaphylactic Shock by Hemocoagulase with Increased Concentration of Mast Cell Tryptase: A case report

Lee SY, Park KS, Cho OG, Kim YS, Jeong WH

Multiple agents can cause anaphylaxis in a perioperative setting. Identifying the agent responsible is essential for avoiding future adverse reactions as well as to attenuate the progression of anaphylaxis. Being...
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Anaphylactic reaction with hydroxyethyl starch during anesthesia: A case report

Kim G, Kim G, Kwon M, Koo M, Yun M

BACKGROUND: Hydroxyethyl starch (HES), a class of synthetic colloid solutions, has been widely used to treat perioperative hypovolemia. The use of HES, however, is associated with the risk of allergic...
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Anaphylaxis to Polyethylene Glycol (Colyte®) in a Patient with Diverticulitis

Lee SH, Hwang SH, Park JS, Park HS, Shin YS

Polyethylene glycols (PEGs) are believed to be chemically inert agents, but larger PEG polymers could have immunogenicity. A 39-year-old man was referred to emergency room for loss of consciousness and...
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Hypersensitivity Reaction to Perioperative Drug Mistaken for Local Anesthetic Systemic Toxicity in a Patient under Brachial Plexus Block

Jun JY, Kim YJ, Kim JH, Han JI

Perioperative anaphylaxis, although rare, is a severe, life-threatening unexpected systemic hypersensitivity reaction. Simultaneous administration of various drugs during anesthesia, the difficulty of communicate with patients in sedation and anesthesia, and...
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A Case of Diclofenac-Induced Anaphylaxis with Elevated Serum Tryptase

  • KMID: 2299672
  • Korean J Asthma Allergy Clin Immunol.
  • 2005 Sep;25(3):228-230.
Diclofenac is a non-steroid anti-inflammatory drug (NSAID), which belongs to the phenylacetic acid group. It is commonly used in inflammatory conditions of various etiologies, degenerative joint disease, rheumatoid arthritis and...
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An unusual case of infant seizures with anaphylaxis to wheat

Chong KW, Ling S, Loh W

Wheat allergy is one of the commonest food allergies in childhood and it typically presents with IgE mediated reactions, including anaphylaxis. Seizures are not typically reported to be a direct...
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Refractory intraoperative hypotension with elevated serum tryptase

Sprung J, Larson KJ, Divekar RD, Butterfield JH, Schwartz L, Weingarten TN

Severe intraoperative hypotension has been reported in patients on angiotensin-converting enzyme inhibitors and angiotensin II receptor subtype 1 antagonists. We describe a patient on lisinopril who developed refractory intraoperative hypotension...
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Recent update of local allergic rhinitis

Cho SH

Rhinitis is a common airway disease that can affect patient's quality of life and social activities. Rhinitis comprises heterogenous diseases and classified as allergic rhinitis (AR) or nonallergic rhinitis (NAR)...
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Anaphylaxis induced by lysozyme in Green cough

Youn TY, Kim MK

Lysozyme is a small protein composed of 129 amino acids with a molecular weight of 14.3 kD. In human, it is in the eye drop, saliva, nasal secretion, and gastric...
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Successful Remission of Recurrent Anaphylaxis after Omalizumab Administration in a Patient with Systemic Mastocytosis

Moon H, Jang HJ, Lee CG, Kim YC, Yoo SH, Lee DS, Kang HR

Mastocytosis is a disorder characterized by abnormal mast cell proliferation and accumulation in one or more tissues. It presents in two major variants: cutaneous mastocytosis and systemic mastocytosis. Because the...
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Role of Mast Cells in Allergic Inflammation and Innate Immunity

Ahn K

  • KMID: 1655406
  • Korean J Pediatr.
  • 2004 Nov;47(11):1137-1141.
Mast cells play a key role in elicitation of the early-phase and late-phase IgE-mediated allergic inflammatory reactions. Mast cells are derived from pluripotent stem cells from the bone marrow. These...
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The effect of trypsin and chymotrypsinon the chemotaxis and activation of eosinophil

Lee MG, Kim MB, Kim JH, Yun TJ, Choi JE, Kim DH, Mo EK, Park MJ, Hyun IG, Jung KS

BACKGROUND: Eosinophilic leukocytes are prominent cellular participants in the pathogenesis of allergic disease and asthma. Chemotaxis is still a very useful method in evaluating the response of human eosinophil to...
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