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Assessment of hemagglutination activity of porcine deltacoronavirus

Zhang Y, Han L, Xia L, Yuan Y, Hu H

Porcine deltacoronavirus (PDCoV) is an emerging swine enteric coronavirus that causes diarrhea in piglets. However, the biological characteristics of PDCoV are unclear. In this study, the hemagglutination (HA) abilities of...
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Serum concentrations of α2-macroglobulin, α1-antitrypsin, and C-reactive protein in dogs with suspected acute pancreatitis

Park S, Kim H, Kang JH, Kang BT, Yang MP

In canine acute pancreatitis (AP), inappropriate release and activation of zymogen proteases within the pancreas results in the consumption of serum antiproteases. The aim of this study was to examine...
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Non-cultured Epidermal Cell Suspension Transplantation Using Suction Blisters to Treat Refractory Vitiligo: A Retrospective Study of 20 Cases

Bae JM, Jung HM, Lee HN, Lee RW, Eun SH, Kwon HS, Lee JH, Kim GM

  • KMID: 2436845
  • Korean J Dermatol.
  • 2018 Aug;56(7):426-432.
BACKGROUND: As nonsurgical interventions for vitiligo are not always successful, various surgical modalities have been used in patients with refractory vitiligo. Of these, non-cultured epidermal suspension transplantation (NCES) was recently...
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Acute Pancreatitis with Purtscher's-like Retinopathy

Han JS, Nam SE, Jang DK, Lee JK

A 28-year-old man with a history of alcohol abuse was diagnosed with acute pancreatitis based on clinical symptoms, laboratory findings and computed tomography findings. On the second day of hospitalization,...
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Structural Analysis of Recombinant Human Preproinsulins by Structure Prediction, Molecular Dynamics, and Protein-Protein Docking

Jung SH, Kim CK, Lee G, Yoon J, Lee M

More effective production of human insulin is important, because insulin is the main medication that is used to treat multiple types of diabetes and because many people are suffering from...
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Efficient Method for the Rapid Purification of Nosema ceranae Spores

Kim DJ, Yun HG, Kim IH, Gwak WS, Woo SD

Nosema ceranae is an obligate intracellular fungal parasite that causes mortality in honey bees and enhances the susceptibility of honey bees to other pathogens. Efficient purification of Nosema spores from...
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PRSS1, SPINK1, CFTR, and CTRC Pathogenic Variants in Korean Patients With Idiopathic Pancreatitis

Cho SM, Shin S, Lee KA

BACKGROUND: This study aimed to identify pathogenic variants of PRSS1, SPINK1, CFTR, and CTRC genes in Korean patients with idiopathic pancreatitis. METHODS: The study population consisted of 116 Korean subjects (65...
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Dietary Triggers in Irritable Bowel Syndrome: Is There a Role for Gluten?

Volta U, Pinto-Sanchez MI, Boschetti , Caio G, De Giorgio R, Verdu EF

  • KMID: 2433448
  • J Neurogastroenterol Motil.
  • 2016 Oct;22(4):547-557.
  • doi: 10.5056/jnm16069
A tight link exists between dietary factors and irritable bowel syndrome (IBS), one of the most common functional syndromes, characterized by abdominal pain/discomfort, bloating and alternating bowel habits. Amongst the...
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Skin Barrier Recovery by Protease-Activated Receptor-2 Antagonist Lobaric Acid

Joo YA, Chung H, Yoon S, Park JI, Lee JE, Myung CH, Hwang JS

Atopic dermatitis (AD) results from gene and environment interactions that lead to a range of immunological abnormalities and breakdown of the skin barrier. Protease-activated receptor 2 (PAR2) belongs to a...
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Fibrin Scaffolds Designing in order to Human Adipose-derived Mesenchymal Stem Cells Differentiation to Chondrocytes in the Presence of TGF-beta3

Sheykhhasan M, Qomi RT, Ghiasi M

BACKGROUND AND OBJECTIVES: One of the most cellular source used for cartilage tissue engineering are mesenchymal stem cells (MSCs). In present study, human MSCs were used as cellular source. Since...
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Allergenic Characterization of a Novel Allergen, Homologous to Chymotrypsin, from German Cockroach

Jeong KY, Son M, Lee JH, Hong CS, Park JW

PURPOSE: Cockroach feces are known to be rich in IgE-reactive components. Various protease allergens were identified by proteomic analysis of German cockroach fecal extract in a previous study. In this...
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Vitamin D Inhibits Expression and Activity of Matrix Metalloproteinase in Human Lung Fibroblasts (HFL-1) Cells

Kim SH, Baek MS, Yoon DS, Park JS, Yoon BW, Oh BS, Park J, Kim HJ

BACKGROUND: Low levels of serum vitamin D is associated with several lung diseases. The production and activation of matrix metalloproteinases (MMPs) may play an important role in the pathogenesis of...
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Proteomic analysis of domestic pig pancreas during development using two-dimensional electrophoresis and matrix-assisted laser desorption/ionization-time of flight mass spectrometry

Ahn JY, Kim IY, Oh SJ, Hwang HS, Yi SS, Kim YN, Shin JH, Yoon YS, Seong JK

Pig pancreas may be a therapeutic resource for human diabetic patients. However, this potential is hindered by a lack of knowledge of the molecular events of pig pancreas development. In...
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The Effect of Urinary Trypsin Inhibitor Against Neuropathic Pain in Rat Models

Jung KT, Lee HY, Yoon MH, Lim KJ

BACKGROUND: Nerve injury sometimes leads to chronic neuropathic pain associated with neuroinflammation in the nervous system. In the case of chronic neuropathic pain, the inflammatory and algesic mediators become predominant...
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Bacteroides fragilis Toxin Induces IL-8 Secretion in HT29/C1 Cells through Disruption of E-cadherin Junctions

Hwang S, Gwon SY, Kim MS, Lee S, Rhee KJ

Enterotoxigenic Bacteroides fragilis (ETBF) is a human gut commensal bacteria that causes inflammatory diarrhea and colitis. ETBF also promotes colorectal tumorigenesis in the Min mouse model. The key virulence factor...
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Pathogenesis of Acute Pancreatitis

Oh TG, Bang S

  • KMID: 2267800
  • Korean J Med.
  • 2013 Aug;85(2):111-115.
Acute pancreatitis is an inflammatory disease that is caused by various etiologies including gallstone, alcohol or hypertriglyceridemia. Although most cases of acute pancreatitis show self-limiting course, severe cases are still...
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Treatment of eggshell with casein phosphopeptide reduces the severity of ovariectomy-induced bone loss

Kim JH, Kim MS, Oh HG, Lee HY, Park JW, Lee BG, Park SH, Moon DI, Shin EH, Oh EK, Erkhembaatar M, Kim O, Lee YR, Chae HJ

It has been generally accepted that calcium intake prevents bone loss, and frequent fracture resulted from osteoporosis. However, it is still elusive as to how effective sole calcium intake is...
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Effects of Ulinastatin on Postoperative Blood Loss and Hemostasis in Atrioventricular Valve Surgery with Cardiopulmonary Bypass

Park JB, Kim SH, Lee SA, Chung JW, Kim JS, Chee HK

BACKGROUND: Cardiopulmonary bypass (CPB) induces variable systemic inflammatory reactions associated with major organ dysfunction via polymorphonuclear neutrophils (PMNs). Ulinastatin, a urinary trypsin inhibitor, inhibits PMN activity and reduces systemic inflammatory...
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Urinary trypsin inhibitor attenuates lipopolysaccharide-induced neutrophil activation

Lee SH, Kim HJ, Han HJ, Li M, Kwak SH, Park S

BACKGROUND: Urinary trypsin inhibitor (UTI), which is speculated to have anti-inflammatory effects, is one of serine protease inhibitors found in human urine and blood. The present study was conducted to...
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Epigenetic Modulation of Gene Expression during Keratinocyte Differentiation

Back SJ, Im M, Sohn KC, Choi DK, Shi G, Jeong NJ, Lee Y, Seo YJ, Kim CD, Lee JH

BACKGROUND: Epigenetic modulation of gene expression occurs by various methods, including DNA methylation and histone modification. DNA methylation of specific genes may affect the chromatin structure, preventing access by the...
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