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Modified Acellularization for Successful Vascular Xenotransplantation

Jo WM, Sohn YS, Choi YH, Kim HJ, Cho HD

The purpose of this study was to estimate the possibilities of an acellular matrix using a modified acellularization protocol, which circumvents immunological, microbiological, and physiological barriers. We treated porcine subclavian...
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64-Channel multi-detector row CT angiographic evaluation of the micropigs for potential living donor lung transplantation

Yoon W, Ryu JM, Lee MY, Moon YJ, Lee SH, Park JH, Yun SP, Jang MW, Park SS, Han HJ

Micropigs are the most likely source animals for xenotransplantation. However, an appropriate method for evaluating the lung of micropigs had not been established. Therefore, this study was performed to evaluate...
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Evaluation of a canine small intestinal submucosal xenograft and polypropylene mesh as bioscaffolds in an abdominal full-thickness resection model of growing rats

Lee AJ, Lee SH, Chung WH, Kim DH, Chung DJ, Do SH, Kim HY

We evaluated the biological scaffold properties of canine small intestinal submucosa (SIS) compared to a those of polypropylene mesh in growing rats with full-thickness abdominal defects. SIS is used to...
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Imaging evaluation of the liver using multi-detector row computed tomography in micropigs as potential living liver donors

Ryu JM, Kim DH, Lee MY, Lee SH, Park JH, Yun SP, Jang MW, Kim SH, Rho GJ, Han HJ

The shortage of organ donors has stimulated interest in the possibility of using animal organs for transplantation into humans. In addition, pigs are now considered to be the most likely...
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Successful Xenograft of Endoscopic Ultrasound-Guided Fine-Needle Aspiration Specimen from Human Extrahepatic Cholangiocarcinoma into an Immunodeficient Mouse

Jang SY, Bae HI, Lee IK, Park HK, Cho CM

Patient-derived tumor xenograft is the transfer of primary human tumors directly into an immunodeficient mouse. Patient-derived tumor xenograft plays an important role in the development and evaluation of new chemotherapeutic...
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