- TGF-beta1 induces mouse dendritic cells to express VEGF and its receptor (Flt-1) under hypoxic conditions
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Nam EH, Park SR, Kim PH
- KMID: 983953
- Exp Mol Med.
- 2010 Sep;42(9):606-613.
- doi: 10.3858/emm.2010.42.9.059
Angiogenesis is a multi-step process that involves the activation, proliferation, and migration of endothelial cells. We have recently shown that TGF-beta1 can induce mouse macrophages to produce VEGF, a potent... -
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- Overexpression of USF Increases TGF-beta1 Protein Levels, But G1 Phase Arrest was not Induced in FRTL-5 Cells
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Kim KS, Jung HS, Chung YJ, Jung TS, Jang HW, Lee MS, Kim KW, Chung JH
- KMID: 1783075
- J Korean Med Sci.
- 2008 Oct;23(5):870-876.
- doi: 10.3346/jkms.2008.23.5.870
Transforming growth factor-beta1 (TGF-beta1) is a potent inhibitor of cellular growth and proliferation by G1 phase arrest or apoptosis. We investigated the association of TGF-beta1 with the anti-proliferative effect of... -
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- Transtorming Growth Factor beta1 Induces Epithelial-to-Mesenchymal Transition of A549 Cells
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Kim JH, Jang YS, Eom KS, Hwang YI, Kang HR, Jang SH, Kim CH, Park YB, Lee MG, Hyun IG, Jung KS, Kim DG
- KMID: 1713300
- J Korean Med Sci.
- 2007 Oct;22(5):898-904.
- doi: 10.3346/jkms.2007.22.5.898
Idiopathic pulmonary fibrosis (IPF) comprises an aggregate of mesenchymal cells. However, the cellular origin of these mesenchymal phenotypes remains unclear. Transforming growth factor beta1 (TGF-beta1) has been known as the... -
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- Inhibition of hepatic stellate cells by bone marrow-derived mesenchymal stem cells in hepatic fibrosis
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Jang YO, Jun BG, Baik SK, Kim MY, Kwon SO
- KMID: 2164364
- Clin Mol Hepatol.
- 2015 Jun;21(2):141-149.
- doi: 10.3350/cmh.2015.21.2.141
BACKGROUND/AIMS: Therapies involving bone-marrow-derived mesenchymal stem cells (BM-MSCs) have considerable potential in the management of hepatic disease. BM-MSCs have been investigated in regenerative medicine due to their ability to secrete... -
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- The dose of cyclophosphamide for treating paraquat-induced rat lung injury
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Choi JS, Jou SS, Oh MH, Kim YH, Park MJ, Gil HW, Song HY, Hong SY
- KMID: 1503779
- Korean J Intern Med.
- 2013 Jul;28(4):420-427.
- doi: 10.3904/kjim.2013.28.4.420
BACKGROUND/AIMS: Cyclophosphamide (CP) is a promising treatment for severe cases of paraquat (PQ) poisoning. We investigated the effective dose of CP for mitigating PQ-induced lung injury. METHODS: Adult male Sprague-Dawley rats... -
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- Simvastatin Reduces Capsular Fibrosis around Silicone Implants
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Chung KJ, Park KR, Lee JH, Kim TG, Kim YH
- KMID: 2373756
- J Korean Med Sci.
- 2016 Aug;31(8):1273-1278.
- doi: 10.3346/jkms.2016.31.8.1273
Capsular fibrosis and contracture occurs in most breast reconstruction patients who undergo radiotherapy, and there is no definitive solution for its prevention. Simvastatin was effective at reducing fibrosis in various... -
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- Effects of Omega-3 Fatty Acids on Erectile Dysfunction in a Rat Model of Atherosclerosis-induced Chronic Pelvic Ischemia
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Shim JS, Kim DH, Bae JH, Moon DG
- KMID: 2363698
- J Korean Med Sci.
- 2016 Apr;31(4):585-589.
- doi: 10.3346/jkms.2016.31.4.585
The aim of this study was to investigate whether the omega-3 fatty acids help to improve erectile function in an atherosclerosis-induced erectile dysfunction rat model. A total of 20 male... -
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- Pulmonary Adenocarcinoma with Heterotopic Ossification
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Kim GY, Kim J, Kim TS, Han J
- KMID: 1779171
- J Korean Med Sci.
- 2009 Jun;24(3):504-510.
- doi: 10.3346/jkms.2009.24.3.504
Pulmonary adenocarcinoma is a common malignancy that often involves calcification; however, bone formation in primary lung adenocarcinoma is extremely rare. In ten cases of primary pulmonary adenocarcinoma with heterotopic ossification,... -
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- Nuclear factor E2-related factor 2 Dependent Overexpression of Sulfiredoxin and Peroxiredoxin III in Human Lung Cancer
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Kim YS, Lee HL, Lee KB, Park JH, Chung WY, Lee KS, Sheen SS, Park KJ, Hwang SC
- KMID: 1022170
- Korean J Intern Med.
- 2011 Sep;26(3):304-313.
- doi: 10.3904/kjim.2011.26.3.304
BACKGROUND/AIMS: Oxidative stress results in protein oxidation and is implicated in carcinogenesis. Sulfiredoxin (Srx) is responsible for the enzymatic reversal of inactivated peroxiredoxin (Prx). Nuclear factor E2-related factor 2 (Nrf2)... -
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- Angiopoietin-1 Modified Human Umbilical Cord Mesenchymal Stem Cell Therapy for Endotoxin-Induced Acute Lung Injury in Rats
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Huang ZW, Liu N, Li D, Zhang HY, Wang Y, Liu Y, Zhang LL, Ju XL
- KMID: 2374208
- Yonsei Med J.
- 2017 Jan;58(1):206-216.
- doi: 10.3349/ymj.2017.58.1.206
PURPOSE: Angiopoietin-1 (Ang1) is a critical factor for vascular stabilization and endothelial survival via inhibition of endothelial permeability and leukocyte- endothelium interactions. Hence, we hypothesized that treatment with umbilical cord... -
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