- Transforming growth factor beta 1 expression in gastric carcinoma
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Park YE, Choi YH, Lee WY, Choi KC
- KMID: 1038392
- J Korean Med Sci.
- 1997 Jun;12(3):215-220.
- doi: 10.3346/jkms.1997.12.3.215
Many types of human malignant tumor have been reported to amplify transforming growth factor-beta 1 (TGF-beta 1) gene and overexpress its protein. However, little work has been... -
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- Regulation of anti-inflammatory cytokines IL-10 and TGF-beta in mouse dendritic cells through treatment with Clonorchis sinensis crude antigen
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Jin Y, Wi HJ, Choi MH, Hong ST, Bae YM
- KMID: 2155339
- Exp Mol Med.
- 2014 Jan;46(1):e74.
- doi: 10.1038/emm.2013.144
Dendritic cells (DCs), which are regarded as the most potent antigen-presenting cells, are involved in innate and adaptive immunity. Upon uptake of pathogens, DCs express cell surface markers and secrete... -
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- Immunomodulatory effects of human amniotic membrane-derived mesenchymal stem cells
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Kang JW, Koo HC, Hwang SY, Kang SK, Ra JC, Lee MH, Park YH
- KMID: 1364999
- J Vet Sci.
- 2012 Mar;13(1):23-31.
- doi: 10.4142/jvs.2012.13.1.23
Human amniotic membrane-derived mesenchymal stem cells (hAM-MSCs) are capable of differentiating into several lineages and possess immunomodulatory properties. In this study, we investigated the soluble factor-mediated immunomodulatory effects of hAM-MSCs.... -
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- Individual or combined effects of enalapril and verapamil on chronic cyclosporine nephrotoxicity in rats
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Lee SK, Park JY, Yu ES, Yang WS, Kim SB, Park SK, Park JS
- KMID: 646042
- J Korean Med Sci.
- 1999 Dec;14(6):653-658.
- doi: 10.3346/jkms.1999.14.6.653
Previous studies have demonstrated that enalapril and verapamil seem to attenuate the cyclosporine nephrotoxicity. However, the mechanisms have not been completely understood, especially on molecular events. The aim of this... -
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- betaig-h3 triggers signaling pathways mediating adhesion and migration of vascular smooth muscle cells through alphavbeta5 integrin
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Lee BH, Bae JS, Park RW, Kim JE, Park JY, Kim IS
- KMID: 1111408
- Exp Mol Med.
- 2006 Apr;38(2):153-161.
Adhesion and migration of vascular smooth muscle cells (VSMCs) play an important role in the pathogenesis of atherosclerosis. These processes involve the interaction of VSMCs with extracellular matrix proteins. Here,... -
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- Microarray for Genes Associated with Signal Transduction in Diabetic OLETF Keratocytes
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Lee JE, Lee JS, Hwang SH
- KMID: 1101914
- Korean J Ophthalmol.
- 2007 Jun;21(2):111-119.
- doi: 10.3341/kjo.2007.21.2.111
PURPOSE: The purpose of this study was to identify differences in signal transduction gene expression between normal and diabetic keratocytes stimulated with interleukin-1alpha (IL-1alpha) and tumor necrosis factor-alpha (TNF-alpha). ... -
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- The immune-stimulating peptide WKYMVm has therapeutic effects against ulcerative colitis
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Kim SD, Kwon S, Lee SK, Kook M, Lee HY, Song KD, Lee HK, Baek SH, Park CB, Bae YS
- KMID: 2154259
- Exp Mol Med.
- 2013 Sep;45(9):e40.
In this study, we examined the therapeutic effects of an immune-stimulating peptide, WKYMVm, in ulcerative colitis. The administration of WKYMVm to dextran sodium sulfate (DSS)-treated mice reversed decreases in body... -
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- Gene expression in uremic left ventricular hypertrophy: effects of hypertension andanemia
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Mak RH, Chang SL, Draksharapu A, Pak YK
- KMID: 1097107
- Exp Mol Med.
- 2004 Jun;36(3):251-258.
Hypertension and anemia may be causes of left ventricular hypertrophy (LVH) in uremia but the molecular mechanism is not known. Uremia was induced in male Spraugue Dawley rats by 5/6... -
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- Granulocyte Colony Stimulating Factor Attenuates Hyperoxia-Induced Lung Injury by Down-Modulating Inflammatory Responses in Neonatal Rats
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Jeon GW, Sung DK, Jung YJ, Koo SH, Choi SH, Chang YS, Sin JB, Park WS
- KMID: 1106439
- Yonsei Med J.
- 2011 Jan;52(1):65-73.
- doi: 10.3349/ymj.2011.52.1.65
PURPOSE: Granulocyte colony stimulating factor (G-CSF) has been known to increase neutrophil production and have anti-inflammatory properties, but the effect of G-CSF on pulmonary system is in controversy. We investigated... -
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- Inhibitory effect of receptor for advanced glycation end products (RAGE) on the TGF-beta-induced alveolar epithelial to mesenchymal transition
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Song JS, Kang CM, Park CK, Yoon HK, Lee SY, Ahn JH, Moon HS
- KMID: 1022128
- Exp Mol Med.
- 2011 Sep;43(9):517-524.
- doi: 10.3858/emm.2011.43.9.059
Idiopathic pulmonary fibrosis (IPF) is a lethal parenchymal lung disease characterized by myofibroblast proliferation. Alveolar epithelial cells (AECs) are thought to produce myofibroblasts through the epithelial to mesenchymal transition (EMT).... -
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