- Protective role of curcumin against lipopolysaccharide-induced inflammation and apoptosis in human neutrophil
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Cho KB, Park CH, Kim J, Tin TD, Kwak SH
- KMID: 2500453
- Anesth Pain Med.
- 2020 Jan;15(1):41-48.
- doi: 10.17085/apm.2020.15.1.41
Background: Sepsis, an uncontrolled host response to infection, may be life-threatening organ injury. Neutrophils play a critical role in regulation of host immune response to infection. Curcumin, known as a... -
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- Effect of BMS-470539 on lipopolysaccharide-induced neutrophil activation
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Lee S, Ju W, Tin TD, Kim J, Lee JS, Park CH, Kwak SH
- KMID: 2501821
- Korean J Anesthesiol.
- 2020 Apr;73(2):151-157.
- doi: 10.4097/kja.19233
Background: BMS-470539, a recently introduced selective agonist of the melanocortin 1 receptor, is known to have anti-inflammatory properties. In this study, we investigated the effects of BMS-470539 on lipopolysaccharide (LPS)-induced... -
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- The Effects of Flecainide Acetate on Inflammatory-Immune Response in Lipopolysaccharide-Stimulated Neutrophils and on Mortality in Septic Rats
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Chung SY, Kim J, Bae HB, Tin TD, Ju W, Kwak SH
- KMID: 2436305
- Acute Crit Care.
- 2018 Feb;33(1):34-41.
- doi: 10.4266/acc.2017.00577
BACKGROUND: Flecainide acetate is a drug used primarily for cardiac arrhythmia. Some studies also imply that flecainide acetate has the potential to regulate inflammatory-immune responses; however, its mechanism of action... -
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- The effects of BMS-470539 on lipopolysaccharide-induced acute lung injury
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Jang EA, Kim JY, Tin TD, Song JA, Lee SH, Kwak SH
- KMID: 2449367
- Acute Crit Care.
- 2019 May;34(2):133-140.
- doi: 10.4266/acc.2019.00507
BACKGROUND: Overactivation of inflammatory cells, including macrophages and neutrophils, is associated with acute lung injury. BMS-470539 is a selective agonist of melanocortin 1 receptor, which triggers the inhibition of proinflammatory... -
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