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rhTSH in Thyroid Cancer

Choe W

  • KMID: 2199898
  • J Korean Soc Endocrinol.
  • 2002 Apr;17(2):143-151.
No abstract available.
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Recent Advances in Radioiodine Therapy for Thyroid Cancer

Bae SK

  • KMID: 2313024
  • Nucl Med Mol Imaging.
  • 2006 Apr;40(2):132-140.
Well-differentiated thyroid cancer is the most common endocrine malignancy with an increasing incidence. Most patients with well-differentiated thyroid caner have a favorable prognosis with high survival rate. While surgery and...
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Value of the Serum Thyroglobulin Level Alteration at the First High Dose Radioiodine Treatment in Patients with Differentiated Thyroid Carcinoma

Nam HY, Kim IJ, Kim YK, Kim SJ, Jun S, Kim BS

  • KMID: 2313104
  • Nucl Med Mol Imaging.
  • 2009 Aug;43(4):294-300.
PURPOSE: The purpose of this study was to evaluate if short-term serum thyroglobulin (Tg) elevation after radioiodine administration can predict successful radioiodine remnant ablation (RRA) and whether comparable RRA effectiveness...
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Economic Evaluation of Recombinant Human Thyroid Stimulating Hormone Stimulation vs. Thyroid Hormone Withdrawal Prior to Radioiodine Ablation for Thyroid Cancer: The Korean Perspective

Sohn SY, Jang HW, Cho YY, Kim SW, Chung JH

BACKGROUND: Previous studies have suggested that recombinant human thyroid stimulating hormone (rhTSH) stimulation is an acceptable alternative to thyroid hormone withdrawal (THW) when radioiodine remnant ablation is planned for thyroid...
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A Retrospective Review of the Effectiveness of Recombinant Human TSH-Aided Radioiodine Treatment of Differentiated Thyroid Carcinoma

Na MA, Shin SH, Kang YH, Son SM, Kim IJ, Kim YK

BACKGROUND: The aim of the study was to evaluate the biochemical effects of recombinant human thyroid stimulating hormone (rhTSH) as an adjunct to radioiodine (RI) treatment of a differentiated thyroid...
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Analysis of the Pharmacokinetics of Recombinant Human TSH in Patients with Thyroid Papillary Carcinoma

Jung TS, Jung HS, Jung JH, Chung YJ, Oh EY, Min YK, Lee MS, Lee MK, Kim KW, Chung JH

BACKGROUND: Individual variations of the pharmacokinetics of recombinant human TSH (rhTSH) might influence the efficacy of the radioactive iodine (RAI) uptake. We studied to investigate the individual pharmacokinetics of rhTSH...
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Does 131I Radioactivity Interfere with Thyroglobulin Measurement in Patients Undergoing Radioactive Iodine Therapy with Recombinant Human TSH?

Park S, Bang JI, Lee HY, Kim SE

OBJECTIVES: Recombinant human thyroid-stimulating hormone (rhTSH) is widely used in radioactive iodine therapy (RIT) to avoid side effects caused by hypothyroidism during the therapy. Owing to RIT with rhTSH, serum...
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Weight Changes in Patients with Differentiated Thyroid Carcinoma during Postoperative Long-Term Follow-up under Thyroid Stimulating Hormone Suppression

Sohn SY, Joung JY, Cho YY, Park SM, Jin SM, Chung JH, Kim SW

BACKGROUND: There are limited data about whether patients who receive initial treatment for differentiated thyroid cancer (DTC) gain or lose weight during long-term follow-up under thyroid stimulating hormone (TSH) suppression....
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Comparison of I-131 Biokinetics after Recombinant Human TSH Stimulation and Thyroid Hormone Withdrawal Measured by External Detector in Patients with Differentiated Thyroid Cancer

Kairemo K, Kangasmäki A, Bom HS

The aim of this study was to compare radioactive iodine (I-131) biokinetics after recombinant human TSH stimulation (rhTSH) and thyroid hormone withdrawal (THW) in patients with differentiated thyroid cancer (DTC)....
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Analysis of Clinical Factors for the Determination of Optimal Serum Level of Thyrotropin After Recombinant Human Thyroid-Stimulating Hormone Administration

Son SH, Lee SW, Jung JH, Kim CY, Kim DH, Jeong SY, Ahn BC, Lee J

PURPOSE: To determine the optimal levels of thyroidstimulating hormone (TSH) levels after administration of recombinant human TSH (rhTSH) to patients with differentiated thyroid cancer (DTC), we have analyzed the clinical...
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Factors That Influence TSH Levels after Thyrogen Injection before RAI Therapy

Kim EY, Yun JS

PURPOSE: Radioactive iodine therapy was used for detection and destruction of remnant normal of malignant thyroid tissue after thyroidectomy for differentiated thyroid gland cancer. To achieve a high level of...
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Clinical Usefulness of the Second Generation TSH-Binding Inhibitory Immunoglobulin Assay Using Recombinant Human TSH Receptor in Patients with Graves' Disease

Huh JE, Suk JH, Kim MK, Choi IJ, Son SM, Kim IJ, Kim YK

BACKGROUND AND AIM: Detection of TSH receptor antibody in patients with Graves' disease (GD) has been widely used in clinical practice. This has been performed mostly by commercial radio-receptor assays...
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Comparison of Thyroglobulin Measurements Using Three Different Immunoassay Kits: A BRAMHS Tg-Plus RIA Kit, a BRAMHS hTg Sensitive Kryptor Kit, and a Beckman Coulter ACCESS Immunoassay Kit

Kim M, Jeon MJ, Kim WG, Lee JJ, Ryu JS, Cho EJ, Ko DH, Lee W, Chun S, Min WK, Kim TY, Shong YK, Kim WB

BACKGROUND: Second-generation thyroglobulin immunometric assays (Tg-IMAs) have been developed with improved sensitivity. Our aim was to compare the diagnostic value of Tg-IMA measurements using a Kryptor (BRAHMS AG) kit (Tg-K)...
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Clinical Significance of Diffuse Intrathoracic Uptake on Post-Therapy I-131 Scans in Thyroid Cancer Patients

Choi HS, Kim SH, Park SY, Park HL, Seo YY, Choi WH

  • KMID: 2139219
  • Nucl Med Mol Imaging.
  • 2014 Mar;48(1):63-71.
PURPOSE: The purpose of this study was to identify the frequency and possible cause of diffuse intrathoracic uptake on post-therapy I-131 scans in thyroid cancer patients. METHODS: We retrospectively reviewed 781...
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Comparison of the Influence on the Liver Function Between Thyroid Hormone Withdrawal and rh-TSH Before High-Dose Radioiodine Therapy in Patients with Well-Differentiated Thyroid Cancer

Han YH, Lim ST, Yun KN, Yim SK, Kim DW, Jeong HJ, Sohn MH

  • KMID: 2052003
  • Nucl Med Mol Imaging.
  • 2012 Jun;46(2):89-94.
PURPOSE: An elevated thyroid stimulating hormone level (TSH) is essential to stimulate the uptake of radioiodine into thyroid remnants and metastases of thyroid cancer when a patient undergoes high-dose radioiodine...
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Postoperative Adjuvant Therapy and Follow-Up of Thyroid Carcinoma

Yi KH

Differentiated thyroid cancer is usually a curable disease, for which treatment modalities such as surgery, radioiodine, and thyroid hormone have been used for the last 50 years, yet little consensus...
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Serum Thyroglobulin Levels Predicting Recurrence and Distant Metastasis after Surgery in Patients with Differentiated Thyroid Cancer

Kim KS, Ryu JS, Hong SJ, Kim WB, Shong YK

  • KMID: 2331171
  • J Korean Soc Endocrinol.
  • 2003 Apr;18(2):153-165.
BACKGROUND: Reports on serum thyroglobulin(Tg) levels being used to predict recurrence or distant metastasis during the follow-up of patients with differentiated thyroid cancer(DTC) has been inconsistent. In addition, there have...
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Comparison of Therapeutic Efficacy and Clinical Parameters Between Recombinant Human Thyroid Stimulating Hormone and Thyroid Hormone Withdrawal in High-Dose Radioiodine Treatment with Differentiated Thyroid Cancer

Choi S, Na CJ, Kim J, Han YH, Kim HK, Jeong HJ, Sohn MH, Lim ST

PURPOSE: High-dose radioiodine treatment (HD-RIT) after injection of recombinant human thyroid stimulating hormone (rh-TSH) has become widely used. This study compared the therapeutic efficacy of HD-RIT and clinical parameters between...
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