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Tetanus toxin fragment C fused to flagellin makes a potent mucosal vaccine

Lee SE, Nguyen CT, Kim SY, Thi TN, Rhee JH

PURPOSE: Recombinant subunit vaccines provide safe and targeted protection against microbial infections. However, the protective efficacy of recombinant subunit vaccines tends to be less potent than the whole cell vaccines,...
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Tetanus Developing after a Traumatic Rectal Rupture: A Case Report

Kim JS, Kim KH, Park SJ, Nam SH, Kim WW, Kim YH

  • KMID: 2297800
  • J Korean Soc Traumatol.
  • 2013 Sep;26(3):214-217.
Tetanus is a neurologic disorder caused by a tetanospasmin released from Clostridium tetani and usually occurs as a result of a dirty open wound or abrasion. Post traumatic tetanus is...
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Synthetic Cannabinoid-Induced Immunosuppression Augments Cerebellar Dysfunction in Tetanus-Toxin Treated Mice

Yun J, Gu SM, Lee TH, Song YJ, Seong S, Kim YH, Cha HJ, Han KM, Shin J, Oh H, Jung K, Ahn C, Park HK, Kim HS

Synthetic cannabinoids are one of most abused new psychoactive substances. The recreational use of abused drug has aroused serious concerns about the consequences of these drugs on infection. However, the...
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Tetanus Developed in Gangrenous Perforation of Small Bowel

Park CM, Choi MG, Noh JH, Sohn TS, Bae JM, Kim S, Suh GY, Jeon KM

Tetanus is a neurologic disorder caused by a tetanospasmin released from Clostridium tetani and usually occurs following a stab wound or dirty abrasion. Tetanus is uncommon in Korea due to...
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One Case of Tetanus after Taking Acupuncture

Hwang IC, Jung RJ, Chee SH, Kang HC

  • KMID: 2294395
  • J Korean Acad Fam Med.
  • 2008 Dec;29(12):948-951.
Tetanus is a neurologic disease which features the muscle spasm as the hallmark. It is an infectious disease with high mortality rate triggered by tetanospasmin produced by Clostridium tetani. This...
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Electrophysiological Tests in Generalized Tetanus

Kim CH, Seo HJ, Cha MJ, Kim MJ, Minn YK, Cho SJ, Ma HI, Kwon KH

  • KMID: 2185245
  • J Korean Neurol Assoc.
  • 2007 Feb;25(1):33-37.
BACKGROUND: Tetanus toxin selectively blocks inhibitory synapses in the brainstem as well as the spinal cord. Therefore, in contradiction to Stiff Person syndrome, patients with generalized tetanus usually show abnormal...
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Age Related Serosurvey of Immunity to Tetanus in Korean Populations

Kang JH, Hur JK, Kim JH, Lee KI, Park SE, Ma SH, Lee MS, Ban SJ, Hong SH, Cho DH, Lee SH

  • KMID: 2305409
  • Korean J Infect Dis.
  • 2001 Apr;33(2):104-111.
BACKGROUND: The incidence of tetanus in adults and neonatal tetanus have been markedly reduced by world-wide use of DTP vaccines. But, tetanus is still one kind of major health problems...
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Effect of the Heat Shock Protein 70 on the Adjuvanticity Induced by a Bacterial Flagellin of Vibrio ulnificus

Lee SE, Bae SJ, Kim SY, Kim YR, Rhee JH

  • KMID: 1574182
  • J Bacteriol Virol.
  • 2005 Dec;35(4):299-306.
Recently we have shown that a bacterial flagellin, Vibrio vulnifiucs FlaB (Vv-FlaB), has a strong adjuvant activity to induce protective immune response. In order to investigate the adjuvanticity of Vv-FlaB,...
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Systemic administration of low dosage of tetanus toxin decreases cell proliferation and neuroblast differentiation in the mouse hippocampal dentate gyrus

Yan BC, Kim IH, Park JH, Ahn JH, Cho JH, Chen BH, Lee JC, Choi JH, Yoo KY, Lee CH, Cho JH, Kim JD, Won MH

In the present study, we investigated the effect of Tetaus toxin (TeT) on cell proliferation and neuroblast differentiation using specific markers: 5-bromo-2-deoxyuridine (BrdU) as an exogenous marker for cell proliferation,...
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