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Anxiolytic Action of Taurine via Intranasal Administration in Mice

Jung JH, Kim SJ

Taurine has a number of beneficial pharmacological actions in the brain such as anxiolytic and neuroprotective actions. We explored to test whether taurine could be transported to the central nervous...
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Metabolomics approach to serum biomarker for laxative effects of red Liriope platyphylla in loperamide-induced constipation of SD rats

Kim JE, Lee YJ, Ryu SH, Park JW, Kang MJ, Choi HJ, Bae SJ, Choi Y, Kang HG, Kim KB, Kim S, Lim Y, Hwang DY

Red Liriope platyphylla (RLP) is a known herbal medicine used in the treatment of some chronic diseases including constipation, neurodegenerative disorders, diabetes and obesity. To determine and characterize putative biomarkers...
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Effects and Mechanisms of Taurine as a Therapeutic Agent

Schaffer S, Kim HW

Taurine is an abundant, β-amino acid with diverse cytoprotective activity. In some species, taurine is an essential nutrient but in man it is considered a semi-essential nutrient, although cells lacking...
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Age-Related Changes in Sulfur Amino Acid Metabolism in Male C57BL/6 Mice

Jeon JS, Oh JJ, Kwak HC, Yun HY, Kim HC, Kim YM, Oh SJ, Kim SK

Alterations in sulfur amino acid metabolism are associated with an increased risk of a number of common late-life diseases, which raises the possibility that metabolism of sulfur amino acids may...
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Cytoprotective Effect of Taurine against Hydrogen Peroxide-Induced Oxidative Stress in UMR-106 Cells through the Wnt/β-Catenin Signaling Pathway

Lou J, Han D, Yu H, Yu G, Jin M, Kim SJ

Osteoporosis development is closely associated with oxidative stress and reactive oxygen species (ROS). Taurine has potential antioxidant effects, but its role in osteoblasts is not clearly understood. The aim of...
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Taurine relaxes human radial artery through potassium channel opening action

Ulusoy KG, Kaya E, Karabacak , Seyrek M, Duvan I, Yildirim V, Yildiz O

The vascular actions and mechanisms of taurine were investigated in the isolated human radial artery (RA). RA rings were suspended in isolated organ baths and tension was recorded isometrically. First,...
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Effects of S-Adenosylmethionine and Its Combinations With Taurine and/or Betaine on Glutathione Homeostasis in Ethanol-induced Acute Hepatotoxicity

Lee SY, Ko KS

BACKGROUND: Exposure to ethanol abuse and severe oxidative stress are risk factors for hepatocarcinoma. The aim of this study was to evaluate the effects of S-adenosylmethionine (SAMe) and its combinations...
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Protective Effects of S-Adenosylmethionine and Its Combinations With Taurine and/or Betaine Against Lipopolysaccharide or Polyinosinic-polycytidylic Acid-induced Acute Hepatotoxicity

Lee SY, Ko KS

BACKGROUND: Several mechanisms for the pathogenesis of many liver diseases are related with oxidative stress, endotoxins, and infections by many microorganisms. These can lead to chronic hepatitis, cirrhosis, and even...
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Urine metabolomic analysis to detect metabolites associated with the development of contrast induced nephropathy

Diercks DB, Owen KP, Kline JA, Sutter ME

OBJECTIVE: Contrast induced nephropathy (CIN) is a result of injury to the proximal tubules. The incidence of CIN is around 11% for imaging done in the acute care setting. We...
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Effects of Awareness and Knowledge of Energy Drinks on Consumption Patterns among College Students

Kim YJ, Jeon EM, Shim SB, Seo HJ

BACKGROUND: We examined the consumption patterns and the knowledge and awareness of energy drinks to draw up a guideline for energy drink consumption and to give accurate information to college...
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Alterations of Amino Acid Level in Depressed Rat Brain

Yang P, Li X, Ni J, Tian J, Jing F, Qu C, Lin L, Zhang H

Amino-acid neurotransmitter system dysfunction plays a major role in the pathophysiology of depression. Several studies have demonstrated the potential of amino acids as a source of neuro-specific biomarkers could be...
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Effects of taurine on cadmium exposure in muscle, gill, and bone tissues of Carassius auratus

Choi KS, Yoo IS, Shin KO, Chung KH

  • KMID: 2313645
  • Nutr Res Pract.
  • 2013 Feb;7(1):22-25.
This study was performed in order to investigate the effects of taurine on cadmium poisoning in muscle, gill, and bone tissues of wild goldfish. For this experiment, 80 wild goldfish...
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The Current Situation of Treatment Systems for Alcoholism in Korea

Kim JW, Lee BC, Kang TC, Choi IG

Alcoholism is becoming one of the most serious issues in Korea. The purpose of this review article was to understand the present status of the treatment system for alcoholism in...
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A case of taurine-containing drink induced anaphylaxis

Lee SE, Lee SY, Jo EJ, Kim MY, Yang MS, Chang YS, Kim SH

Taurine is one of most abundant free amino acids in mammalian tissue. It has been used for various health functional foods as a main ingredient in food industry. A 33-year-old...
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Taxol and Taurine Protect the Renal Tissue of Rats after Unilateral Ureteral Obstruction: A Stereological Survey

Karbalay-Doust S, Noorafshan A, Pourshahid SM

  • KMID: 2315587
  • Korean J Urol.
  • 2012 May;53(5):360-367.
PURPOSE: Blockage of the urinary tract induces changes in renal structure including tubular dilatation or atrophy, tubular cell death, inflammatory processes, and progressive interstitial fibrosis with the loss of renal...
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Taurine ameliorates hyperglycemia and dyslipidemia by reducing insulin resistance and leptin level in Otsuka Long-Evans Tokushima fatty (OLETF) rats with long-term diabetes

Kim KS, Oh DH, Kim JY, Lee BG, You JS, Chang KJ, Chung H, Yoo MC, Yang HI, Kang JH, Hwang YC, Ahn KJ, Chung HY, Jeong IK

  • KMID: 1401758
  • Exp Mol Med.
  • 2012 Nov;44(11):665-673.
This study aimed to determine whether taurine supplementation improves metabolic disturbances and diabetic complications in an animal model for type 2 diabetes. We investigated whether taurine has therapeutic effects on...
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Alzheimer's Disease: Clinical Trials and Future Perspectives

Lee KS, Suh HS

  • KMID: 2287462
  • Korean J Psychopharmacol.
  • 2012 Oct;23(4):131-135.
Alzheimer's disease is increasingly common in elderly population with a large socioeconomic burden. Current available drugs for Alzheimer's disease are acetylcholinesterase inhibitors and N-methyl-D-aspartate receptor antagonist. Much effort is directed...
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Neurobiological and Clinical Characteristics According to Lesch's Typology in Alcohol Dependence

Choi MR, Chai YG, Lee BH, Lee JS

  • KMID: 2250132
  • Korean J Biol Psychiatry.
  • 2011 Aug;18(3):109-118.
OBJECTIVES: Many studies have suggested different neurobiological findings and clinical courses in alcoholism. Recently, subtyping in alcohol dependence has become essential to overcome the heterogeneity of patients. Among several criteria...
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Immediate Anticoagulation for Acute Cardioembolic Stroke is Still Popular in Selective Cases in Korea

Lee JH, Park KY, Heo JH, Kwon SU

BACKGROUND: Although current guidelines do not recommend immediate anticoagulation therapy (IAC) for acute ischemic stroke, judicious debates are still lingering on whether it might be done for acute cardioembolic stroke...
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Alcohol and brain health: from mechanisms to interventions

Min JA, Kim DJ, Lee CU

Alcohol-related problems are prevalent and lead to substantial economic, physical, and psychological burden. Among the various effects of alcohol, the effect on the brain is a matter of importance. The...
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