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Synaptic Transmission of Cochlear Inner Hair Cells

Lee SH

  • KMID: 2276728
  • Korean J Otolaryngol-Head Neck Surg.
  • 2007 Apr;50(4):284-290.
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Effect of Brain-derived Neurotrophic Factor on Excitatory Synaptic Transmission in Hippocampal Neurons

Song DK, Son EI, Hong YS, Bae JH, Park WK

  • KMID: 1546027
  • Korean J Aerosp Environ Med.
  • 1999 Jun;9(2):192-197.
Brain-derived neurotrophic factor (BDNF) rapidly enhances synaptic transmission among the hippocampal neurons in the resting state. This mechanism may be due to the phosphorylation of NMDA receptors through its Trkb...
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Modulation of Amygdala Synaptic Transmission by Metabotropic Glutamate Receptors

Kim JH, Park EJ, Chang DJ, Choi S

  • KMID: 1607513
  • Korean J Physiol Pharmacol.
  • 2003 Dec;7(6):303-306.
Metabotropic glutamate receptors (mGluRs), classified into three groups (group I, II, III), play a critical role in modulation of synaptic transmission at central and peripheral synapses. In the present study,...
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Molecular Mechanisms Involved in Depotentiation and Their Relevance to Schizophrenia

Sanderson

Long-term potentiation (LTP) and long-term depression (LTD) of synaptic transmission are forms of synaptic plasticity that have been studied extensively and are thought to contribute to learning and memory. The...
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Effects of Modafinil on Behavioral Learning and Hippocampal Synaptic Transmission in Rats

Yan WW, Yao LH, Chen C, Wang HX, Li CH, Huang JN, Xiao P, Liu CY

PURPOSE: Modafinil is a wake-promoting agent that has been proposed to improve cognitive performance at the preclinical and clinical levels. Since there is insufficient evidence for modafinil to be regarded...
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Changes in Synaptic Transmission and Long-term Potentiation Induction as a Possible Mechanism for Learning Disability in an Animal Model of Multiple Sclerosis

Mosayebi G, Soleyman M, khalili M, Mosleh M, Palizvan M

PURPOSE: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. It has been shown that memory deficits is common in patients with MS. Recent studies...
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Presynaptic Dysfunction by Familial Factors in Parkinson Disease

Lee W, Koh S, Hwang S, Kim SH

Parkinson disease (PD) is the second most prevalent neurodegenerative disorder after Alzheimer disease. The loss of specific brain area, the substantia nigra pars compacta is known as a major etiology,...
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Fluoxetine Modulates Corticostriatal Synaptic Transmission through Postsynaptic Mechanism

Cho HS, Choi SJ, Kim KJ, Lee HH, Cho YJ, Kim SY, Sung KW

  • KMID: 1512939
  • Korean J Physiol Pharmacol.
  • 2006 Feb;10(1):31-38.
Fluoxetine, widely used for the treatment of depression, is known to be a selective serotonin reuptake inhibitor (SSRI), however, there are also reports that fluoxetine has direct effects on several...
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Dopamine Modulates Corticostriatal Synaptic Transmission through Both D1 and D2 Receptor Subtypes in Rat Brain

Lee HH, Choi SJ, Kim KJ, Cho HS, Kim SY, Sung KW

  • KMID: 1600108
  • Korean J Physiol Pharmacol.
  • 2005 Oct;9(5):263-268.
Striatum has important roles in motor control, habitual learning and memory. It receives glutamatergic inputs from neocortex and thalamus, and dopaminergic inputs from substantia nigra. We examined effects of dopamine...
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Layer-specific cholinergic modulation of synaptic transmission in layer 2/3 pyramidal neurons of rat visual cortex

Cho KH, Lee SY, Joo K, Rhie DJ

It is known that top-down associative inputs terminate on distal apical dendrites in layer 1 while bottom-up sensory inputs terminate on perisomatic dendrites of layer 2/3 pyramidal neurons (L2/3 PyNs)...
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NMDA Receptor-dependent Inhibition of Synaptic Transmission by Acute Ethanol Treatment in Rat Corticostriatal Slices

Choi SJ, Kim KJ, Cho HS, Kim SY, Yim DS, Cho YJ, Hahn SJ, Sung KW

  • KMID: 1587467
  • Korean J Physiol Pharmacol.
  • 2006 Dec;10(6):303-307.
The effects of ethanol on corticostriatal synaptic transmission were examined, using extracellular recording and analysis of population spike amplitudes in rat brain slices, to study how acute ethanol intoxication impairs...
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In Vivo Measurement of Dopaminergic Neurotransmission

Kim SE

  • KMID: 2078654
  • Korean J Nucl Med.
  • 1997 Nov;31(4):401-420.
No abstract available.
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Psychiatric Implication for the Regulation of AMPA Receptor

Oh D, Lee E

  • KMID: 2299868
  • Korean J Biol Psychiatry.
  • 2013 Feb;20(1):1-5.
Glutamate receptors are important components of synaptic transmission in the nervous system. Especially, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors mediate most abundant excitatory synaptic transmission in the brain. There is elaborate...
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Inhibitory Modulation of 5-Hydroxytryptamine on Corticostriatal Synaptic Transmission in Rat Brain Slice

Choi SJ, Chung WS, Kim KJ, Sung KW

  • KMID: 1607512
  • Korean J Physiol Pharmacol.
  • 2003 Dec;7(6):295-301.
Striatum plays a crucial role in the movement control and habitual learning. It receives an information from wide area of cerebral cortex as well as an extensive serotonergic (5-hydroxytryptamine, 5-HT)...
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Mind Bomb-2 Regulates Hippocampus-dependent Memory Formation and Synaptic Plasticity

Kim S, Kim T, Lee HR, Kong YY, Kaang BK

Notch signaling is a key regulator of neuronal fate during embryonic development, but its function in the adult brain is still largely unknown. Mind bomb-2 (Mib2) is an essential positive...
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5-Hydroxytryptamine Inhibits Glutamatergic Synaptic Transmission in Rat Corticostriatal Brain Slice

Cho HS, Choi SJ, Kim KJ, Lee HH, Kim SY, Cho YJ, Sung KW

  • KMID: 1600107
  • Korean J Physiol Pharmacol.
  • 2005 Oct;9(5):255-262.
Striatum is involved in the control of movement and habitual memory. It receives glutamatergic input from wide area of the cerebral cortex as well as an extensive serotonergic (5-hydroxytryptamine, 5-HT)...
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Peripheral Nerve Injury Alters Excitatory and Inhibitory Synaptic Transmission in Rat Spinal Cord Substantia Gelatinosa

Youn DH

  • KMID: 1600055
  • Korean J Physiol Pharmacol.
  • 2005 Jun;9(3):143-147.
Following peripheral nerve injury, excessive nociceptive inputs result in diverse physiological alterations in the spinal cord substantia gelatinosa (SG), lamina II of the dorsal horn. Here, I report the alterations...
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Effects of nociceptin/orphanin FQ on excitatory synaptic transmission in rat trigeminal caudal neurons

Chun SW, Min SK

  • KMID: 2183972
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2003 May;25(3):214-221.
The caudal subnucleus of the spinal trigeminal nucleus(medullary dorsal horn:MDH) is implicated in the processing of nociceptive information in the orofacial region. In the present study, whole cell patch clamp...
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Salvia miltiorrhiza Bunge Blocks Ethanol-Induced Synaptic Dysfunction through Regulation of NMDA Receptor-Dependent Synaptic Transmission

Park HJ, Lee S, Jung JW, Lee YC, Choi SM, Kim DH

Consumption of high doses of ethanol can lead to amnesia, which often manifests as a blackout. These blackouts experienced by ethanol consumers may be a major cause of the social...
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Nitric Oxide Modulation of GABAergic Synaptic Transmission in Mechanically Isolated Rat Auditory Cortical Neurons

Lee JJ

The auditory cortex (A1) encodes the acquired significance of sound for the perception and interpretation of sound. Nitric oxide (NO) is a gas molecule with free radical properties that functions...
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