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Morphological changes of the stria vascularis in the absence ofadrenocorticosteroid hormones

Park CW, Ahn KS, Kim SK

  • KMID: 1684438
  • Korean J Otolaryngol-Head Neck Surg.
  • 1992 Feb;35(1):22-33.
No abstract available.
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The Changes of Na+-K+ ATPase Activity and Ultrastructure of Endolymphatic Secretory Epithelium by Local and Systemic Streptomycin Treatment

Chung WK, Kim HN, Lee WS, Chi JH

  • KMID: 2274367
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 Nov;40(11):1616-1631.
The endolymphatic secretory epithelium are stria vascularis in cochlear and dark cell in vestibule which are regulated by Na+-K+ ATPase. It is important that we study intracytoplasmic Na+-K+ ATPase for...
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The expression of voltage-dependent K+ channels in stria vascularis of the guinea pig cochlea

Kang SH, Kim BH, Lim DJ, Lee MJ, Lee BD, Chang HS

  • KMID: 2275710
  • Korean J Otolaryngol-Head Neck Surg.
  • 2001 Jul;44(7):688-695.
BACKGROUND AND OBJECTIVES: An ion channel is one of the basic structures of a cell that maintain the homeostasis to control the excitation, secretion, motility, growth and volume of cells....
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Expression of Voltage-dependent Na+ Channels in the Albino Guinea Pig Cochlea

Lee SW, Lee SK, Cho NS, Song TH, Lee BD, Chang HS, Kang JW, Kim YJ

  • KMID: 2275619
  • Korean J Otolaryngol-Head Neck Surg.
  • 2001 Jan;44(1):15-20.
BACKGROUND AND OBJECTIVES: The endolymph produced from cochlear lateral wall regulates fluid and maintains positive endocochlear potential. Although many immunohistochemical studies of ion transport enzymes in the cochlear lateral wall...
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Morphological Changes of Cochlear Structures after Cisplatin Administration

Kim BH, Lim DJ, Lee GS, Ryu JM, Lee BY

  • KMID: 1887267
  • Korean J Otolaryngol-Head Neck Surg.
  • 2002 Jun;45(6):538-543.
BACKGROUND AND OBJECTIVES: Cisplatin is frequently used in the treatment of various forms of malignancies. It's therapeutic efficacy, however, is limited due to the occurrence of sensorineural hearing loss. Little...
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Expression of Insulin-like Growth Factors in a Mouse Model of Salicylate Ototoxicity

Im GJ, Choi J, Chang JW, Kim SJ, Kim HI, Jung HH

  • KMID: 2278606
  • Clin Exp Otorhinolaryngol.
  • 2010 Sep;3(3):115-121.
OBJECTIVES: Insulin-like growth factors (IGFs) are known to be neurotrophic factors, and they efficiently signal to cells to grow, differentiate and survive. The purpose of study was to identify the...
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Immune-mediated Inner Ear Dysfunction Caused by Histones, as Planted Target Antigens

Park KY, Cho CS, Kim JW, Lee GW, Lee CH, Hozawa K, Takasaka T

  • KMID: 1887273
  • Korean J Otolaryngol-Head Neck Surg.
  • 2002 Jun;45(6):574-578.
BACKGROUND AND OBJECTIVES: Histones, a set of highly cationic proteins essentially involved in the binding and packing of DNA in the cell nucleus chromatin, have five subclasses (H1, H2a, H2b,...
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Effect of Steroid Administration on Immune-Mediated Sensorineural Hearing Loss in MRL/MP-lpr/lpr Mice

Park KY, Kim JB, Cho CH, Cho CS, Hozawa K, Takasaka T

  • KMID: 2074288
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 May;40(5):725-731.
In our daily clinical practice, we have come across several patients suffering from a fluctuating sensorineural hearing loss of unknown origin. Such patients were sometimes treated with sucess by steroid...
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Comparison of Cochlear Morphology and Apoptosis in Mouse Models of Presbycusis

Park SN, Back SA, Park KH, Kim DK, Park SY, Oh JH, Park YS, Yeo SW

  • KMID: 2278608
  • Clin Exp Otorhinolaryngol.
  • 2010 Sep;3(3):126-135.
OBJECTIVES: Morphological studies on presbycusis, or age-related hearing loss, have been performed in several different strains of mice that demonstrate hearing loss with auditory pathology. The C57BL/6 (C57) mouse is...
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Histochemical Staining of PetaNADPH Diaphorase in Mongolian Gerbil and CJU/A Mouse Cochleae

Choo MJ, Kim JS, Song CK, Shin SO, Jin HR

  • KMID: 1977711
  • Korean J Otolaryngol-Head Neck Surg.
  • 1999 Nov;42(11):1343-1348.
BACKGROUND AND OBJECTIVES: Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. The histochemical demonstration of neuronal betaNADPH-d is the demonstration of...
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Expression of FGF-R and TGF-R in the Lateral Wall of the Guinea Pig

Lee BD, Kim SH, Ahn HY, Chang HS, Kang JW

  • KMID: 1886938
  • Korean J Otolaryngol-Head Neck Surg.
  • 1999 May;42(5):547-551.
BACKGROUND AND OBJECTIVES: The endolymph produced from cochlear lateral wall regulates fluid balance and maintains positive endocochlear potentials. Although many immunohistochemical studies on ion transport enzymes have been reported, their...
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Cochlear Pathology in Experimental Otitis Media with Effusion ofGuinea Pig Caused by Endotoxin

Jung HH, Kim YH, Sung TH, Jung DK

  • KMID: 2274518
  • Korean J Otolaryngol-Head Neck Surg.
  • 1998 Dec;41(12):1527-1535.
BACKGROUND AND OBJECTIVES: Injection of endotoxin into the middle ear of experimental animals results in otitis media with effusion and transient reversible hearing loss, which occurs in the higher concentration...
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Expression and Distribution of Tumor Necrosis Factor-Alpha in Mice Cochlea Exposed to Noise

Jo MH, Kim CJ, Koh SH, Nam GS, Jeong HM, Lee JH, Lee SH

BACKGROUND AND OBJECTIVES: Recent studies have shown that inflammatory responses occur in the inner ear under various damaging conditions including noise-overstimulation.Identification of time-dependent expression patterns of pro-inflammatory cytokines during the...
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Noise Induced Changes of Glucocorticoid Receptors in Rat Cocohlea

You JS, Lim HH, Choi JO

  • KMID: 2274304
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 Feb;40(2):277-285.
It has been suggested that glucocorticoid receptors are present in inner ear tissues and may act in stress related mechanism of cochlea. The purpose of this study was to determine...
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Light and Scaning Electromicroscopic Study on the Experimental on the Experimental Endolymphatic Hydrops in Guinea Pigs

Oh SH, Jung HW, Kang BS, Kwon TK, Kim CS

  • KMID: 1920896
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 Dec;40(12):1715-1721.
BACKGROUND: Despite numerous investigations, the pathogenesis of Meniere's disease is uncertain. Endolymphatic hydrops (ELH) has been the main histologic finding of Meniere's disease. Experimentally induced ELH in animal model has...
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Expression of Bax and Bcl-2 in Apoptosis of the Rat Cochlea Induced by Acute Cisplatin Ototoxicity

Kim CS, Song BH, Koo JW, Lim DW

  • KMID: 2275663
  • Korean J Otolaryngol-Head Neck Surg.
  • 2001 Jun;44(6):565-571.
BACKGROUND AND OBJECTIVES: Cisplatin is an ototoxic agent commonly used for the treatment of solid tumors. Recently, it has been recognized to cause apoptosis in tumor cells, kidney and cochlea....
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Effect of Ebselen on Noise Induced Cochlear Damage

Park YH, Lee YW, Park SW, Koo BS, Kim YM, Rha KS, Park CI

  • KMID: 2276488
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Oct;48(10):1211-1218.
BACKGROUND AND OBJECTIVES: With the advancement of modern civilization and mechanical development of society, the prevalence of noiseinduced hearing loss is increasing. There were some suggestions that noise-induced hearing loss...
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Cochlear Damage Caused by the Striking Noise of Titanium Head Golf Driver

Park YH, Chung J, Lee MY, Lee DY, Kim YH

OBJECTIVES.: To investigate how mouse cochleae are affected by the striking noise of titanium head golf driver. METHODS.: Thirty-two BALB/c mice (20–22 g) with normal hearing were used. The impact acoustic...
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Expression Changes of Endothelin-1, Endothelin Receptor A and B in the Cochlea after Noise Exposure

Hur GM, Lyu AR, Han WK, Choi JW, Rha KS, Park YH

BACKGROUND AND OBJECTIVES: There are several evidences of reduced cochlea blood flow after noise exposure in the cochlea. However, the pathophysiology of blood flow change is still obscure, and endothelins,...
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Immunohistochemical Localization of Na/K-APTase Subunit Isoforms in Rat Inner Ear

Kim HJ, Sohn JH, Lee SW, Kim BY, Ahn KY

  • KMID: 2040103
  • Korean J Anat.
  • 1999 Aug;32(4):583-591.
The endolymph and perilymph of the inner ear have unique ionic composition and electrical potential. It is widely accepted that normal auditory function depends on them and Na/K-ATPase plays a...
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