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Effect of suramin on differentiation of human stomach cancer cell lines

Choe G, Kim WH, Park JG, Kim YI

This study was designed to demonstrate that differentiation of stomach cancer cells can be modified by microenvironmental change and to look for a method inducing or promoting tumor cell...
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Distribution of 5-Fluorouracil-14C in Body Tissues after Systemic and Regional Administration in Gastric Cancer

Min JS, Ban JM, Kim MW, Kim CK, Ryu KJ

This study was to determine which of two routes of administration of 5-fluorouracil (5-FU) is more effective, by measuring the radioactvity in the body tissues of gastric cancer patients after...
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Clinical Characteristics of Pulmonary Embolism with Underlying Malignancy

Lee JE, Kim HR, Lee SM, Yim JJ, Yoo CG, Kim YW, Han SK, Shim YS, Yang SC

BACKGROUND/AIMS: The risk of venous thromboembolism (VTE), which encompasses deep vein thrombosis and pulmonary embolism (PE), increases in patients with cancer. Anticancer treatment is also associated with an increased risk...
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Spontaneous acute tumor lysis syndrome with advanced gastric cancer

Woo IS, Kim JS, Park MJ, Lee MS, Cheon RW, Chang HM, Ahn JS, Lee JA, Park YI, Park YS, Shim JW, Yang I

Acute tumor lysis syndrome (TLS) occurs frequently in hematologic malignancies such as high-grade lymphomas and acute leukemia, which are rapidly proliferating and chemosensitive tumors. It occurs rarely in solid tumors...
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Locally advanced unresectable gastric cancer successfully resected after neoadjuvant chemotherapy with FADE regimen

Chung HC, Roh JK, Park YJ, Lee SI, Min JS, Lee JT, Lee KB, Kim BS

The prognosis of unresectable advanced gastric cancer is extremely poor. We tried a neoadjuvant chemotherapy in locally advanced unresectable stomach cancer diagnosed by initial explo-laparotomy. After chemotherapy with the FADE...
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Adjuvant Treatment with Chemotherapeutic Agents and Polyadenylic-Polyuridylic Acid in Operable Stomach Cancers: I. Enhancement of Natural Killer Cell Activity

Youn JK, Kim BS, Min JS, Choi HJ, Lee YB, Lee DW, Koh EH, Kim KW, Lee KB, Michelson

Natural Killer (NK) cell activity of 47 operable stomach cancer patients was sequentially studied before and after chemotherapy in association with polyadenylic. polyuridylic acid [poly(A).poly(U)]. NK activity was determined by...
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Hepatocyte Growth Factor/c-Met Signaling in Regulating Urokinase Plasminogen Activator in Human Stomach Cancer: A Potential Therapeutic Target for Human Stomach Cancer

Lee KH, Choi EY, Hyun MS, Jang BI, Kim TN, Kim SW, Song SK, Kim JH, Kim JR

BACKGROUND: Up-regulation of the hepatocyte growth factor (HGF), its transmembrane tyrosine kinase receptor (c-Met), and urokinase type plasminogen activator (uPA), is associated with the development and metastasis of various...
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Suppressive Effect of 19-nor-1alpha-25-Dihydroxyvitamin D2 on Gastric Cancer Cells and Peritoneal Metastasis Model

Park MR, Lee JH, Park MS, Hwang JE, Shim HJ, Cho SH, Chung IJ, Bae WK

The active metabolite of vitamin D, 1,25-dihydroxyvitamin D3 (calcitriol), inhibits the growth of several types of human cancer cells in vitro, but its therapeutic use is limited because it causes...
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Nail Changes During Docetaxel Containing Combination Chemotherapy

Woo IS, Shim KH, Kim GY, Lee MA, Kang JH, Hong YS, Lee KS

  • KMID: 759702
  • Korean J Intern Med.
  • 2004 Jun;19(2):132-133.
Nail toxicity following systemic chemotherapy is common. Onychopathy during the period of neutropenia following chemotherapy may cause subungual abscesses and serious infection. Despite taxoid-related toxicity being increasingly reported since 2000,...
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Combination chemotherapy of oral 5'-deoxy-5-fluorouridine and cisplatin in advanced gastric cancer: a phase II study

Ahn MJ, Han DS, Sohn JH, Jeon YC, Jun DW, Choi NW, Park HK, Baik HK, Lee HG, Nam YS, Choi IY

This study was designed to test the activity and feasibility of 5'-deoxy-5-fluorouridine (5'-DFUR) and cisplatin combination therapy in the treatment of advanced gastric cancer. Nineteen patients with inoperable and/or ...
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A randomized trial comparing cisplatin plus 5-fluorouracil with or without levamisole in operable gastric cancer

Choi JS, Lee KH, Ahn MJ, Lee JS, Lee JH, Zang DY, Suh CW, Kim SW, Kim WG, Kim JC, Kim S, Park KC, Lee MS, Kim SH

  • KMID: 1051578
  • Korean J Intern Med.
  • 1997 Jun;12(2):155-162.
OBJECTIVES: To determine the effectiveness and toxicity when levamisole was added to the adjuvant combination chemotherapy in patients with operable gastric cancer. METHODS: After en bloc resection of gastric cancer...
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Blockade of VEGFR-1 and VEGFR-2 Enhances Paclitaxel Sensitivity in Gastric Cancer Cells

Hwang JE, Lee JH, Park MR, Kim DE, Bae WK, Shim HJ, Cho SH, Chung IJ

PURPOSE: Hypoxia-inducible factor-1alpha (HIF-1alpha) increases transcription of the vascular endothelial growth factor (VEGF) gene. Inhibition of VEGF abolishes VEGF mediated induction of HIF-1alpha. Recent reports suggested that HIF-1alpha also mediated...
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