- Stem Cell Properties of Therapeutic Potential
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Seo GS
- KMID: 1018399
- Korean J Gastroenterol.
- 2011 Sep;58(3):125-132.
- doi: 10.4166/kjg.2011.58.3.125
Stem cell research is a innovative technology that focuses on using undifferentiated cells able to self-renew through the asymmetrical or symmetrical divisions. Three types of stem cells have been studied... -
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- Very small embryonic-like stem-cell optimization of isolation protocols: an update of molecular signatures and a review of current in vivo applications
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Shin DM, Suszynska , Mierzejewska K, Ratajczak , Ratajczak
- KMID: 2154275
- Exp Mol Med.
- 2013 Nov;45(11):e56.
As the theory of stem cell plasticity was first proposed, we have explored an alternative hypothesis for this phenomenon: namely that adult bone marrow (BM) and umbilical cord blood (UCB)... -
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- Evaluation of Stem Cell Components in Retrocorneal Membranes
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Lee SH, Kim KW, Kim MK, Chun YS, Kim JC
- KMID: 1796949
- J Korean Med Sci.
- 2014 Jun;29(6):846-851.
- doi: 10.3346/jkms.2014.29.6.846
The purpose of this study was to elucidate the origin and cellular composition of retrocorneal membranes (RCMs) associated with chemical burns using immunohistochemical staining for primitive cell markers. Six cases... -
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- Understanding of molecular mechanisms in natural killer cell therapy
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Yoon SR, Kim TD, Choi I
- KMID: 2155406
- Exp Mol Med.
- 2015 Feb;47(2):e141.
- doi: 10.1038/emm.2014.114
Cancer cells and the immune system are closely related and thus influence each other. Although immune cells can suppress cancer cell growth, cancer cells can evade immune cell attack via... -
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- Overexpression of bone morphogenetic protein 4 in STO fibroblast feeder cells represses the proliferation of mouse embryonic stem cells in vitro
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Kim GH, Lee GR, Choi HI, Park NH, Chung HT, Han IS
- KMID: 1397450
- Exp Mol Med.
- 2012 Jul;44(7):457-463.
Embryonic stem cells (ESCs) can be propagated in vitro on feeder layers of mouse STO fibroblast cells. The STO cells secrete several cytokines that are essential for ESCs to maintain... -
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- Reactive oxygen species enhance differentiation of human embryonic stem cells into mesendodermal lineage
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Ji AR, Ku SY, Cho MS, Kim YY, Kim YJ, Oh SK, Kim SH, Moon SY, Choi YM
- KMID: 946650
- Exp Mol Med.
- 2010 Mar;42(3):175-186.
- doi: 10.3858/emm.2010.42.3.018
Recently, reactive oxygen species (ROS) have been studied as a regulator of differentiation into specific cell types in embryonic stem cells (ESCs). However, ROS role in human ESCs (hESCs) is... -
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- Hematologic Recovery after Tandem High-Dose Chemotherapy and Autologous Stem Cell Transplantation in Children with High-Risk Solid Tumors
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Son MH, Kim DH, Lee SH, Yoo KH, Sung KW, Koo HH, Kim JY, Cho EJ, Kang ES, Kim DW
- KMID: 1429184
- J Korean Med Sci.
- 2013 Feb;28(2):220-226.
- doi: 10.3346/jkms.2013.28.2.220
Although the number of studies using tandem high-dose chemotherapy and autologous stem cell transplantation (HDCT/autoSCT) for the treatment of high-risk pediatric solid tumors has been increasing, documentation of hematologic recovery... -
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- Ischemic Stroke in Rats Enhances Bone Resorption in Vitro
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Chung ME, Lee JI, Im S, Park JH
- KMID: 1792984
- J Korean Med Sci.
- 2012 Jan;27(1):84-88.
- doi: 10.3346/jkms.2012.27.1.84
We hypothesized that the formation and differentialtion of osteoclasts are accelerated and the potential of bone resorption is increased in the hemiplegic bone marrow in the early stage of stroke.... -
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- Modulation of cartilage differentiation by melanoma inhibiting activity/cartilage-derived retinoic acid-sensitive protein (MIA/CD-RAP)
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Schubert T, Schlegel J, Schmid R, Opolka A, Grassel S, Humphries , Bosserhoff AK
- KMID: 946649
- Exp Mol Med.
- 2010 Mar;42(3):166-174.
- doi: 10.3858/emm.2010.42.3.017
Melanoma inhibiting activity/cartilage-derived retinoic acid-sensitive protein (MIA/CD-RAP) is a small soluble protein secreted from malignant melanoma cells and from chondrocytes. Recently, we revealed that MIA/CD-RAP can modulate bone morphogenetic protein... -
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- Contralaterally transplanted human embryonic stem cell-derived neural precursor cells (ENStem-A) migrate and improve brain functions in stroke-damaged rats
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Chang DJ, Oh SH, Lee N, Choi C, Jeon I, Kim HS, Shin DA, Lee SE, Kim D, Song J
- KMID: 2154272
- Exp Mol Med.
- 2013 Nov;45(11):e53.
The transplantation of neural precursor cells (NPCs) is known to be a promising approach to ameliorating behavioral deficits after stroke in a rodent model of middle cerebral artery occlusion (MCAo).... -
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- Disease-specific induced pluripotent stem cells: a platform for human disease modeling and drug discovery
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Jang J, Yoo JE, Lee JA, Lee DR, Kim JY, Huh YJ, Kim DS, Park CY, Hwang DY, Kim HS, Kang HC, Kim DW
- KMID: 1245263
- Exp Mol Med.
- 2012 Mar;44(3):202-213.
- doi: 10.3858/emm.2012.44.3.015
The generation of disease-specific induced pluripotent stem cell (iPSC) lines from patients with incurable diseases is a promising approach for studying disease mechanisms and drug screening. Such innovation enables to... -
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- Human Urine-derived Stem Cells Seeded Surface Modified Composite Scaffold Grafts for Bladder Reconstruction in a Rat Model
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Lee JN, Chun SY, Lee HJ, Jang YJ, Choi SH, Kim DH, Oh SH, Song PH, Lee JH, Kim JK, Kwon TG
- KMID: 2359959
- J Korean Med Sci.
- 2015 Dec;30(12):1754-1763.
- doi: 10.3346/jkms.2015.30.12.1754
We conducted this study to investigate the synergistic effect of human urine-derived stem cells (USCs) and surface modified composite scaffold for bladder reconstruction in a rat model. The composite scaffold... -
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