- Spatial Learning and Memory Using a Radial Arm Maze with a Head-Mounted Display
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Kim H, Park JY, Kim K(
- KMID: 2425504
- Psychiatry Investig.
- 2018 Oct;15(10):935-944.
- doi: 10.30773/pi.2018.06.28.3
OBJECTIVE: A radial arm maze (RAM) is an essential tool for assessing spatial learning and memory. Although this tool is widely used to study deficits in spatial memory in animal... -
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- Identification of Vestibular Organ Originated Information on Spatial Memory in Mice
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Han GC, Kim M, Kim MJ
- KMID: 2436244
- Res Vestib Sci.
- 2018 Dec;17(4):134-141.
- doi: 10.21790/rvs.2018.17.4.134
OBJECTIVES: We aimed to study the role of vestibular input on spatial memory performance in mice that had undergone bilateral surgical labyrinthectomy, semicircular canal (SCC) occlusion and 4G hypergravity exposure. METHODS:... -
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- Differential Effects of Pentoxifylline on Learning and Memory Impairment Induced by Hypoxic-ischemic Brain Injury in Rats
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Halis H, Bitiktaş , Baştuğ O, Tan B, Kavraal S, Güneş T, Süer C
- KMID: 2457402
- Clin Psychopharmacol Neurosci.
- 2019 Aug;17(3):388-399.
- doi: 10.9758/cpn.2019.17.3.388
OBJECTIVE: Hypoxic-ischemic (HI) brain injury in the human perinatal period often leads to significant long-term neurobehavioral dysfunction in the cognitive and sensory-motor domains. Using a neonatal HI injury model (unilateral... -
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- Effects of Chronic and Acute Lithium Treatment on the Long-term Potentiation and Spatial Memory in Adult Rats
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Yousef M, Kavraal Å, Artış AS, Süer C
- KMID: 2456726
- Clin Psychopharmacol Neurosci.
- 2019 Mar;17(2):233-243.
- doi: 10.9758/cpn.2019.17.2.233
OBJECTIVE: Although, accumulating evidence is delineating a neuroprotective and neurotrophic role for lithium (Li), inconsistent findings have also been reported in human studies especially. Moreover, the effects of Li infusion... -
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- Exploratory, cognitive, and depressive-like behaviors in adult and pediatric mice exposed to controlled cortical impact
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Lee SW, Jang MS, Jeong SH, Kim H
- KMID: 2452985
- Clin Exp Emerg Med.
- 2019 Jun;6(2):125-137.
- doi: 10.15441/ceem.18.019
OBJECTIVE: Sequelae of behavioral impairments associated with human traumatic brain injury (TBI) include neurobehavioral problems. We compared exploratory, cognitive, and depressive-like behaviors in pediatric and adult male mice exposed to... -
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- β-Sitosterol treatment attenuates cognitive deficits and prevents amyloid plaque deposition in amyloid protein precursor/presenilin 1 mice
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Ye JY, Li L, Hao QM, Qin Y, Ma CS
- KMID: 2466568
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):39-46.
- doi: 10.4196/kjpp.2020.24.1.39
Alzheimer's disease (AD) is the most common neurodegenerative disorder causing dementia worldwide, and is mainly characterized by aggregated β-amyloid (Aβ). Increasing evidence has shown that plant extracts have the potential... -
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- Treadmill Exercise Improves Memory Function Depending on Circadian Rhythm Changes in Mice
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Hwang DS, Kwak HB, Ko IG, Kim SE, Jin JJ, Ji ES, Choi HH, Kwon OY
- KMID: 2362507
- Int Neurourol J.
- 2016 Nov;20(Suppl 2):S141-S149.
- doi: 10.5213/inj.1632738.369
PURPOSE: Exercise enhances memory function by increasing neurogenesis in the hippocampus, and circadian rhythms modulate synaptic plasticity in the hippocampus. The circadian rhythm-dependent effects of treadmill exercise on memory function... -
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- Spatial Learning and Motor Deficits in Vacuolar Protein Sorting-associated Protein 13b (Vps13b) Mutant Mouse
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Kim MJ, Lee RU, Oh J, Choi JE, Kim H, Lee K, Hwang SK, Lee JH, Lee JA, Kaang BK, Lim CS, Lee YS
- KMID: 2458546
- Exp Neurobiol.
- 2019 Aug;28(4):485-494.
- doi: 10.5607/en.2019.28.4.485
Vacuolar protein sorting-associated protein 13B (VPS13B), also known as COH1, is one of the VPS13 family members which is involved in transmembrane transport, Golgi integrity, and neuritogenesis. Mutations in the... -
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- Genistein attenuates isoflurane-induced neurotoxicity and improves impaired spatial learning and memory by regulating cAMP/CREB and BDNF-TrkB-PI3K/Akt signaling
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Jiang T, Wang XQ, Ding C, Du XL
- KMID: 2395252
- Korean J Physiol Pharmacol.
- 2017 Nov;21(6):579-589.
- doi: 10.4196/kjpp.2017.21.6.579
Anesthetics are used extensively in surgeries and related procedures to prevent pain. However, there is some concern regarding neuronal degeneration and cognitive deficits arising from regular anesthetic exposure. Recent studies... -
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- Development and Validation of the Way-Finding Ability Scale for Middle-Aged and Older Adults
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Kim S, Kang Y
- KMID: 2442725
- Dement Neurocogn Disord.
- 2017 Dec;16(4):95-103.
- doi: 10.12779/dnd.2017.16.4.95
BACKGROUND AND PURPOSE: This study was performed to newly develop the Way-Finding Ability Scale (WFAS) for middle-aged and older adults and validate its clinical utility. METHODS: The participants for verifying construct... -
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- Treadmill Exercise Alleviates Circadian Rhythm Disruption-Induced Memory Deficits by Activation of Glucocorticoid Receptor and Brain-Derived Neurotrophic Factor-Dependent Pathway
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Kim SE, Ko IG, Ji ES, Jin JJ, Hwang L, Kim SH, Cho S, Kim CJ, Kim K, Kim KH
- KMID: 2448806
- Int Neurourol J.
- 2019 Feb;23(Suppl 1):S40-S49.
- doi: 10.5213/inj.1938048.024
PURPOSE: Circadian rhythm affects learning process, memory consolidation, and long-term memory. In this study, the alleviating effect of exercise on circadian rhythm disruption-induced memory deficits was investigated. METHODS: BMAL1 knockdown transgenic... -
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- Neuroprotective Effect of Lacosamide on Hypoxic-Ischemic Brain Injury in Neonatal Rats
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Kim GH, Byeon JH, Eun BL
- KMID: 2376014
- J Clin Neurol.
- 2017 Apr;13(2):138-143.
- doi: 10.3988/jcn.2017.13.2.138
BACKGROUND AND PURPOSE: Lacosamide (LCM) is an antiepileptic drug that enhances the slow inactivation of sodium channels and modulates collapsin response mediator protein-2. LCM was recently demonstrated to exert a... -
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