- Anti-inflammatory and Anti-oxidant Effects of Sophora flavescens Root Extraction in Lipopolysaccharide-activated Raw 264.7 Cells
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Lee DH, Sohn DS, Cho DY, Kim BJ, Lim YY, Kim YH
- KMID: 1459237
- Korean J Med Mycol.
- 2010 Jun;15(2):39-50.
BACKGROUND: The macrophages activated by lipopolisaccharide produce numerous molecules and proteins, such as tumor necrotic factor-alpha (TNF-alpha), interleukin-6 (IL-6), IL-1beta, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and free radicals,... -
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- In vitro Effect of Sophora flavescens on the Ultrastructure of Trichomonas vaginalis Donne
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Choi WG, Cho YJ, Chu JP
- KMID: 2082960
- Korean J Infect Dis.
- 2002 Aug;34(4):248-254.
BACKGROUND: Trichomonas vaginalis is a pathogenic protozoa infecting human genitourinary tract. Metronidazole is currently the drug of choice to treat T. vaginalis infection. However, because of the side effects and... -
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- Optimization of Submerged Fermentation Medium for Matrine Production by Aspergillus terreus, an Endophytic Fungus Harboring Seeds of Sophora flavescens, Using Response Surface Methodology
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Zhang Q, Li Y, Xu F, Zheng M, Xi X, Zhang X, Han C
- KMID: 2385656
- Mycobiology.
- 2017 Jun;45(2):90-96.
- doi: 10.5941/MYCO.2017.45.2.90
Different endophytes isolated from the seeds of Sophora flavescens were tested for their ability to produce matrine production. Response surface methodology (RSM) was applied to optimize the medium components for... -
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- GC/MS analysis of high-performance liquid chromatography fractions from Sophora flavescens and Torilis japonica extracts and their in vitro anti-neosporal effects on Neospora caninum
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Seo HS, Kim KH, Kim DY, Park BK, Shin NS, Kim JH, Youn H
- KMID: 1705553
- J Vet Sci.
- 2013 Sep;14(3):241-248.
- doi: 10.4142/jvs.2013.14.3.241
We analyzed alcoholic extracts of herbs possessing anti-neosporal activity against Neospora (N.) caninum. To identify the chemical components of Sophora (S.) flavescens and Torilis (T.) japonica associated with anti-neosporal activity,... -
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- Sedative Effect of Sophora flavescens and Matrine
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Lee HJ, Lee SY, Jang D, Chung SY, Shim I
- KMID: 2386905
- Biomol Ther.
- 2017 Jul;25(4):390-395.
- doi: 10.4062/biomolther.2016.156
The present study investigated the sedative effects of Sophora flavescens (SF) and its bioactive compound, matrine through performing locomotor activity test and the electroencephalography (EEG) analysis in the rat. The... -
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- Antibacterial and therapeutic effects of a combination of Sophora flavescens and Glycyrrhiza uralensis Fischer ethanol extracts on mice infected with Streptococcus pyogenes
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Yu EA, Cha CN, Park EK, Yoo CY, Kim S, Lee HJ
- KMID: 1726751
- Korean J Vet Res.
- 2014 Sep;54(3):189-192.
This study evaluated the antibacterial effects of a mixture of Sophorae radix and Glycyrrhiza uralensis Fischer (1 : 1) ethanol extracts (SGE) on mice infected with Streptococcus (S.) pyogenes. The... -
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- O-glucogenistein inhibits eosinophil recruitment and nasal allergic symptoms in a murine model of nasal allergy
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Jin HR, Sohn B, Zhe YX, Kim YS, Jung SH, Lee SH, Ryu JC, Kim MK
- KMID: 2285835
- J Asthma Allergy Clin Immunol.
- 2003 Sep;23(3):467-473.
BACKGROUND: Infiltration of eosinophils in the nasal mucosa is a consistent feature of nasal allergic inflammation. Various cytokines, especially interleukin-5(IL-5), were identified to play important roles in the infiltration and... -
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- Suppression of nitric oxide and interleukin-6 production by methanol extract of Sophorae Flos in macrophage cells
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Lee JE, Lee JY, Choi JI, Kim CK, Kim SJ
- KMID: 1962389
- J Korean Acad Periodontol.
- 2005 Mar;35(1):9-19.
- doi: 10.5051/jkape.2005.35.1.9
Both nitric oxide (NO) and interleukin-6 (IL-6) have been thought to have a role in the pathogenesis of inflammatory periodontal disease as it does in other inflammatory diseases, and the... -
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- Effects of Sophorae Radix Extracts on the Expression of Cell Cycle Regulatory Proteins in Human Gingival Fibroblasts
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Kim HS, Kim HA, You YO, Kang TH, Kim YC, Kim T, Pee SH, You HK, Shin HS
- KMID: 2116959
- J Korean Acad Periodontol.
- 2000 Dec;30(4):869-883.
- doi: 10.5051/jkape.2000.30.4.869
Fibroblasts are major cellular components of gingiva and periodontal ligament. They regulate the healing process after surgery or injury. Recently, many natural medicines, whose advantages are less side effects and... -
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- The Effect of the Mixed Herbal Extract Lotion for Korean Patient with Atopic Dermatitis: A Pilot Study
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- KMID: 2299478
- Korean J Asthma Allergy Clin Immunol.
- 2012 Mar;32(1):26-33.
BACKGROUND: The choice of topical agents is very important for patients with atopic dermatitis (AD) because mild to moderate AD-related symptoms and skin lesions could be significantly relieved with appropriate... -
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