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Are Solifenacin and Ramosetron Really Ideal to Treat Irritable Bowel Syndrome?: Author's Reply

Suzuki H, Matsuzaki

  • KMID: 2325961
  • J Neurogastroenterol Motil.
  • 2012 Oct;18(4):459-459.
No abstract available.
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Are Solifenacin and Ramosetron Really Ideal to Treat Irritable Bowel Syndrome?

Chang FY

  • KMID: 2325960
  • J Neurogastroenterol Motil.
  • 2012 Oct;18(4):457-458.
No abstract available.
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Pharmacokinetics comparison of solifenacin tartrate and solifenacin succinate: a randomized, open-label, single-dose, 2-way crossover study in healthy male volunteers

Kim YM, Jeon JY, Moon SJ, Jung J, Son H, Kim MG

Solifenacin is a muscarinic antagonist indicated for the treatment of overactive bladder with symptoms. Solifenacin tartrate is a newly developed salt formulation of solifenacin. This study compared the pharmacokinetic and...
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Efficacy of Solifenacin on Irritable Bowel Syndrome With Diarrhea: Open-label Prospective Pilot Trial

Fukushima , Suzuki H, Matsuzaki , Kiyosue A, Hibi T

  • KMID: 2325931
  • J Neurogastroenterol Motil.
  • 2012 Jul;18(3):317-323.
BACKGROUND/AIMS: Solifenacin, a muscarinic type 3 receptor antagonist, is used to treat overactive bladder in adults. The aim of this study is to examine the efficacy of solifenacin on the...
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Efficacy and Safety of Solifenacin Succinate for Urinary Difficulty in Brain Lesion: Multicenter Prospective Study

Bok SK, Lim JH, Cho KH, Choi ES, Kim SS, Lee YJ, Park NK

OBJECTIVE: We studied the efficacy and safety of solifenacin for urinary difficulty in brain lesion from multicenter prospective study. METHOD: Eighty patients with brain lesion who visited from 5 multicenter department...
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Influence of Daytime or Nighttime Dosing with Solifenacin for Overactive Bladder with Nocturia: Impact on Nocturia and Sleep Quality

Kwon T, Oh TH, Choi S, Cho WY, Min K, Lee JZ, Moon KH

We compared changes in nocturia and sleep-related parameters between daytime and nighttime solifenacin dosing in patents with overactive bladder (OAB) and nocturia. We comparatively analyzed the data of a 12-week...
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Meta-Analysis of the Efficacy and Safety of Mirabegron Add-On Therapy to Solifenacin for Overactive Bladder

Xu Y, Liu R, Liu C, Cui Y, Gao Z

PURPOSE: We performed a meta-analysis to evaluate the efficacy and safety of mirabegron add-on therapy to solifenacin for patients with overactive bladder (OAB). METHODS: We conducted a systematic literature review to...
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Antimuscarinic Agent Treatment Affecting Patient-Reported Outcomes in Overactive Bladder Syndrome With Depressive Symptoms

Kim KS, Moon HS

PURPOSE: We investigated improvements in overactive bladder symptoms and depressive symptoms after solifenacin treatment in overactive bladder patients with or without depressive symptoms. METHODS: We performed a prospective study of patients...
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Influence of solifenacin on the improvement of storage symptoms in the early period after photoselective vaporization of the prostate

Kim SJ, Bae WJ, Kim SW

PURPOSE: We studied the effect of solifenacin on reducing storage symptoms after photoselective vaporization of the prostate (PVP). MATERIALS AND METHODS: This study included patients with persistent storage symptoms of urgency...
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Social, Economic, and Medical Factors Associated With Solifenacin Therapy Compliance Among Workers Who Suffer From Lower Urinary Tract Symptoms

Kosilov KV, Alexandrovich LS, Gennadyevna KI, Viktorovna SO, Sergeevna , Ivanovich

PURPOSE: The prevalence of hyperactive-type lower urinary tract symptoms is 45.2%, with shares of overactive bladder (OAB) and urge incontinence (UI) symptoms of 10.7% and 8.2%, respectively. We investigated the...
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Clinical Factors Associated With Dose Escalation of Solifenacin for the Treatment of Overactive Bladder in Real Life Practice

Chun JY, Song M, Han JY, Na S, Hong B, Choo MS

  • KMID: 2232917
  • Int Neurourol J.
  • 2014 Mar;18(1):23-30.
PURPOSE: To determine the baseline clinical characteristics associated with dose escalation of solifenacin in patients with overactive bladder (OAB). METHODS: We analyzed the data of patients with OAB (micturition frequency >...
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Efficacy and Tolerability of Solifenacin 5 mg Fixed Dose in Korean Children with Newly Diagnosed Idiopathic Overactive Bladder: a Multicenter Prospective Study

Lee SD, Chung JM, Kang DI, Ryu DS, Cho WY, Park S

We investigated the efficacy and tolerability of solifenacin 5 mg fixed dose in children with newly diagnosed idiopathic overactive bladder (OAB). A total of 34 children (male/female patients = 16/18)...
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Changes in attention variables in those who treated with anticholinergic agents for nonmonosymptomatic enuresis

Jang G, Im YJ, Suh J, Park K

PURPOSE: Brain dysfunction related to areas regarding attention and arousal may occur not only in patients with attention-deficit/hyperactivity disorder (ADHD) but also in patients with enuresis and daytime symptoms. This...
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Assessment of Anticholinergic Use After Fading of BTX-A Effects in Refractory Idiopathic Overactive Bladder: A Prospective Blinded Randomized Trial

Elbaset MA, Taha DE, El-Hefnawy AS, Zahran MH, Shokeir AA

PURPOSE: To evaluate the efficacy and safety of re-treatment with anticholinergics on refractory idiopathic overactive bladder (OAB) previously treated with intravesical botulinum neurotoxin type A (BTX-A) injections. METHODS: One hundred patients...
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Influence of the Short-term Intake of High Doses of Solifenacin and Trospium on Cognitive Function and Health-Related Quality of Life in Older Women With Urinary Incontinence

Kosilov K, Kuzina I, Loparev S, Gainullina Y, Kosilova L, Prokofyeva A

PURPOSE: The aim of this study was to investigate the safety and the effects of elevated doses of solifenacin and trospium on cognitive function and health-related quality of life (HRQoL)...
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Effects of Tamsulosin, Solifenacin, and Combination Therapy for the Treatment of Ureteral Stent Related Discomforts

Lim KT, Kim YT, Lee TY, Park SY

  • KMID: 2315443
  • Korean J Urol.
  • 2011 Jul;52(7):485-488.
PURPOSE: To evaluate the effect of tamsulosin, solifenacin, and combination therapy of two agents in improving the lower urinary tract symptoms of patients with indwelling double-J ureteral stents. MATERIALS AND METHODS:...
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Impact of Lower Urinary Tract Symptoms/Benign Prostatic Hyperplasia Treatment with Tamsulosin and Solifenacin Combination Therapy on Erectile Function

Seo DH, Kam SC, Hyun JS

  • KMID: 2315650
  • Korean J Urol.
  • 2011 Jan;52(1):49-54.
PURPOSE: To examine the effects on erectile function of concomitant treatment with an alpha-blocker (tamsulosin) and an antimuscarinic agent (solifenacin) in patients with lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia...
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Clinical Efficacy of Solifenacin in the Management of Diabetes Mellitus-Associated Versus Idiopathic Overactive Bladder Symptoms: A Multicenter Prospective Study

Choi H, Bae JH, Oh CY, Jeong SJ, Ko WJ, Choi JB, Seo JT, Lee DH, Kim JC, Lee KW, Kim YH

PURPOSE: To compare the clinical efficacy of anticholinergics for managing diabetes mellitus-associated overactive bladder (DM OAB) versus idiopathic overactive bladder (OAB) in Korean women. METHODS: We conducted a multicenter, prospective, parallel-group,...
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Review of the Anticholinergics for the Treatment of Overactive Bladder: 2009 Update

Oh SJ

  • KMID: 2331537
  • J Korean Continence Soc.
  • 2009 Jun;13(1):7-22.
Overactive bladder is a chronic condition defined by bothersome urgency with or without urgency incontinence, usually associated with daytime frequency and nocturia. The treatment of this condition is to control...
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Characterization of Bladder Selectivity of Antimuscarinic Agents on the Basis of In Vivo Drug-Receptor Binding

Yamada S, Kuraoka S, Osano A, Ito Y

  • KMID: 2232961
  • Int Neurourol J.
  • 2012 Sep;16(3):107-115.
The in vivo muscarinic receptor binding of antimuscarinic agents (oxybutynin, solifenacin, tolterodine, and imidafenacin) used to treat urinary dysfunction in patients with overactive bladder is reviewed. Transdermal administration of oxybutynin...
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