- Frequently Identified Genetic Developmental and Epileptic Encephalopathy: A Review Focusing on Precision Medicine
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Ko A, Kang HC
- KMID: 2449920
- Ann Child Neurol.
- 2019 Mar;27(1):2-12.
- doi: 10.26815/acn.2019.00066
In this article, we reviewed current knowledge regarding gene-specific therapies for some developmental and epileptic encephalopathy caused by genes with high diagnostic yields, and which are therefore, also more frequently... -
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- A Case of Sudden Cardiac Death due to Pilsicainide-Induced Torsades de Pointes
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Nakatani S, Taniike M, Makino N, Egami Y, Shutta R, Tanouchi J, Nishino M
- KMID: 2223902
- Korean Circ J.
- 2014 Mar;44(2):122-124.
- doi: 10.4070/kcj.2014.44.2.122
An 84-year-old male received oral pilsicainide, a pure sodium channel blocker with slow recovery kinetics, to convert his paroxysmal atrial fibrillation to a sinus rhythm; the patient developed sudden cardiac... -
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- Agonistforthe Control of Apotosis through the Study of Cytokine Expression after Spinal CordInjuryin Rats
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Yang JY, Riew KD
- KMID: 2106383
- J Korean Orthop Assoc.
- 2007 Feb;42(1):106-114.
- doi: 10.4055/jkoa.2007.42.1.106
Purpose: To analyze the cytokines that appear after a spinal cord injury in rats and to determine the agonists that regulate apoptosis. Materials and Methods: Sixty female Sprague-Dawley rats were anesthetized,... -
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- Intrathecal Lamotrigine Attenuates Mechanical Allodynia and Suppresses Microglial and Astrocytic Activation in a Rat Model of Spinal Nerve Ligation
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Choi YS, Jun IG, Kim SH, Park JY
- KMID: 1503892
- Yonsei Med J.
- 2013 Mar;54(2):321-329.
- doi: 10.3349/ymj.2013.54.2.321
PURPOSE: Lamotrigine, a novel anticonvulsant, is a sodium channel blocker that is efficacious in certain forms of neuropathic pain. Recently, microglial and astrocytic activation has been implicated in the development... -
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- The Effects of Flecainide Acetate on Inflammatory-Immune Response in Lipopolysaccharide-Stimulated Neutrophils and on Mortality in Septic Rats
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Chung SY, Kim J, Bae HB, Tin TD, Ju W, Kwak SH
- KMID: 2436305
- Acute Crit Care.
- 2018 Feb;33(1):34-41.
- doi: 10.4266/acc.2017.00577
BACKGROUND: Flecainide acetate is a drug used primarily for cardiac arrhythmia. Some studies also imply that flecainide acetate has the potential to regulate inflammatory-immune responses; however, its mechanism of action... -
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