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A case of postoperative serotonin syndrome following the administration of fentanyl, palonosetron, and meperidine: A case report

Lee C, Kim EJ, Joe S, Ban JS, Lee JH, An JH

Serotonin syndrome is an unexpected adverse reaction of serotonergic medication. Some drugs used by anesthesiologists may cause serotonin syndrome. Serotonin syndrome is known to be related to 5-hydroxytryptamine 1A and...
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Probable tramadol-induced atypical serotonin syndrome in a patient receiving selective serotonin reuptake inhibitor and stopped at 10 days before surgery: A case report

Kang Y, Min J, Chae YK, Lee SE, Je UJ, Lee YK

  • KMID: 1797472
  • Anesth Pain Med.
  • 2014 Apr;9(2):115-118.
Tramadol can increase the serum level of serotonin, causing serotonin syndrome, which is a potentially life-threatening condition. Serotonin syndrome occurs when tramadol is used in combination with other drugs that...
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A Case of Serotonin Syndrome Induced by Fluoxetine and Duloxetine Independently in a Same Patient

You S, Noh JS

  • KMID: 2287474
  • Korean J Psychopharmacol.
  • 2012 Apr;23(2):74-77.
Here we report a case of serotonin syndrome caused by fluoxetine 20 mg and duloxetine 60 mg independently eight week apart. A 65-year old man developed fever, agitation and change...
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Serotonin Syndrome in Traumatic Brain Injury Patient: A case report

Song Y, Park I

  • KMID: 2323154
  • J Korean Acad Rehabil Med.
  • 1998 Oct;22(5):1141-1144.
We report a 47-year old traumatic brain injury male patient who was treated for the rigidity and tremor with sinemet (carbidopa levodopa) and artane (trihexyphenidyl). He came to the emergency...
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Famotidine-induced reversal of meperidine-related serotonin syndrome: a case report

Joe S, Kim E, Park J, Lee D, Son J, Kim H

Serotonin syndrome is an unexpected fatal adverse event related to serotonergic medication. This case report is the first report describing the possible treatment effect of famotidine on serotonin syndrome. Furthermore,...
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Two Cases of Serotonin Syndrome

Kwak YT, Han IW, Kang SS, Koo MS, Kim OJ

  • KMID: 1905142
  • J Korean Neurol Assoc.
  • 1999 Jul;17(4):591-596.
We report 2 cases of serotonin syndrome with variable symptoms after being treated with antidepressants. A 57-year-old woman developed agitation, diaphoresis, and tremor after combination therapy with fluoxetine and trazodone....
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Serotonin Syndrome After an Overdose of Dextromethorphan and Chlorpeniramine: Two Case Reports

Jung KY, Yun SH, Jung HM, Kim JH, Han SB, Kim JS, Paik JH

  • KMID: 1482713
  • J Korean Soc Clin Toxicol.
  • 2013 Jun;11(1):19-22.
Dextromethorphan and chlorpeniramine are common ingredients of over-the-counter (OTC) cough pills. They are known to be safe when used alone, however, combination with other serotonergic drugs or use of an...
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A Case of Serotonin Syndrome Due to Amantadine and Escitalopram in End-Stage Renal Disease

Choi JS, Lee EK

  • KMID: 2263510
  • Korean J Med.
  • 2012 Jul;83(1):122-126.
Serotonin syndrome is a potentially life-threatening adverse drug reaction caused by excessive serotonergic activity in the nervous system. It is characterized by a triad of mental status changes, autonomic hyperactivity,...
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Serotonin Syndrome following Duloxetine Administration in a Fibromyalgia Patient: Case Report and Literature Review

Choi JS, Lee JH, Park SK, Shim BJ, Choi WK, Kim SH, Hwang SC

Serotonin syndrome, an adverse drug reaction, is a consequence of excess serotonergic agonism of central nervous system receptors and peripheral serotonergic receptors. Serotonin syndrome has been associated with large numbers...
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Codeine Precipitating Serotonin Syndrome in a Patient in Therapy with Antidepressant and Triptan

Milano G, Natta WM, Bello A, Martelli A, Mattioli F

The serotonin syndrome is a serioius medical condition due due to an intensive stimulation of setonin receptors. It is a rare, but severe, consequence of interaction between serotomimetic agents. This...
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A Case of Severe Serotonin Syndrome Induced by Fluoxetine and Sertraline

Cheon JS, Lee SS, Kim SH, Cho W

  • KMID: 2142175
  • J Korean Soc Biol Psychiatry.
  • 2001 Jun;8(1):167-174.
A 54-year-old male patient who was suffering from bipolar I disorder for 19 years and was admitted to the National Bugok Mental Hospital due to a depressive episode, was referred...
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Neurotoxic Syndrome Developed after Taking Sertraline and Risperidone

Kim JM, Lee ST, Song EC, Jung KH, Sinn DI, Chung H, Chu K, Kim M

Neuroleptic malignant syndrome and serotonin syndrome share many common clinical features, and the term "Neurotoxic syndrome" can be used when a clear distinction cannot be made between the two. Here...
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Agomelatine: The Novel Antidepressant

Woo YS, Wang HR, Bahk WM

  • KMID: 2287863
  • Korean J Psychopharmacol.
  • 2014 Jan;25(1):1-10.
Major depression is a common mental illness, associated with high morbidity and mortality. Antidepressants have been the first-line therapies due to their confirmed efficacy, however, considering high rate of poor...
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Agomelatine: Antidepressant with a New Mechanism of Action

Moon HJ, Bahk WM

  • KMID: 2287388
  • Korean J Psychopharmacol.
  • 2009 Nov;20(6):283-292.
Currently available pharmacotherapies for depression still have a limited antidepressant efficacy with a delayed onset of several weeks, and still cause side effects. These unmet needs represent important reasons to...
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Serotonin Syndrome after Clomipramine Overdose in a Child

Direk MC, Yıldırım V, Güneş S, Bozlu G, Okuyaz C

Serotonin syndrome (SS) is a potentially life-threatening condition associated with increased serotonergic activity in central nervous system and may occur during the use of serotonergic drugs. Although increasing frequency of...
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Serotonin syndrome associated with linezolid

Jeon DS, Nam YH, Kim SH, Choi WJ, Kim EB, Lee HW, Nam HJ, Song JE, Lee SK

Serotonin syndrome (SS) is a potentially life-threatening drug reaction characterized by mental status change, increased neuromuscular tone, and autonomic instability. Linezolid, an oxazolidinone antibacterial agent, is widely used in general...
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Severe complications of tramadol overdose in Iran

Habibollahi P, Garjani A, Shams Vahdati S, Sadat-Ebrahimi SR, Parnianfard N

OBJECTIVES: Severe complications of tramadol overdose have been reported; however, few large-scale studies have investigated this issue. Therefore, this study aimed to explore the presentation and complications of tramadol overdose...
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