- IL-4 Independent Nuclear Translocalization of STAT6 in HeLa Cells by Entry of Toxoplasma gondii
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Ahn HJ, Kim JY, Nam HW
- KMID: 1720620
- Korean J Parasitol.
- 2009 Jun;47(2):117-124.
- doi: 10.3347/kjp.2009.47.2.117
Toxoplasma gondii provokes rapid and sustained nuclear translocation of the signal transducer and activator of transcription 6 (STAT6) in HeLa cells. We observed activation of STAT6 as early as 2... -
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- An Association Study of the Signal Transducer and Activator of Transcription 6 Gene With Periodic Psychosis
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Kawashige , Kanazawa T, Tsutsumi A, Kikuyama H, Uenishi H, Koh J, Yoneda H
- KMID: 2315784
- Psychiatry Investig.
- 2008 Mar;5(1):41-44.
OBJECTIVE: Recent molecular and genetic investigations have suggested that the current nosology for major psychiatric disorders, based on the "two-entities-principal" is not accurate with respect to clinical observations; patient groups... -
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- 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (EC-18) Modulates Th2 Immunity through Attenuation of IL-4 Expression
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Yoon SY, Kang HB, Ko YE, Shin SH, Kim YJ, Sohn KY, Han YH, Chong S, Kim JW
- KMID: 2168035
- Immune Netw.
- 2015 Apr;15(2):100-109.
- doi: 10.4110/in.2015.15.2.100
Controlling balance between T-helper type 1 (Th1) and T-helper type 2 (Th2) plays a pivotal role in maintaining the biological rhythm of Th1/Th2 and circumventing diseases caused by Th1/Th2 imbalance.... -
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- IL-13 and STAT6 signaling involve in low dose lipopolysaccharide induced murine model of asthma
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Bang BR, Lee HS, Lee SY, Chun E, Kim YK, Cho SH, Min KU, Kim YY, Park HW
- KMID: 2397313
- Asia Pac Allergy.
- 2013 Jul;3(3):194-199.
- doi: 10.5415/apallergy.2013.3.3.194
BACKGROUND: We reported that level of lipopolysaccharide (LPS) exposure determined the type of airway inflammation in a murine model of asthma. OBJECTIVE: The purpose of this study is to evaluated the... -
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- Regulation of Systemic Glucose Homeostasis by T Helper Type 2 Cytokines
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Kang YE, Kim HJ, Shong M
- KMID: 2460948
- Diabetes Metab J.
- 2019 Oct;43(5):549-559.
- doi: 10.4093/dmj.2019.0157
Obesity results in an inflammatory microenvironment in adipose tissue, leading to the deterioration of tissue protective mechanisms. Although recent studies suggested the importance of type 2 immunity in an anti-inflammatory... -
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- Afatinib Reduces STAT6 Signaling of Host ARPE-19 Cells Infected with Toxoplasma gondii
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Yang Z, Ahn HJ, Park YH, Nam HW
- KMID: 2374014
- Korean J Parasitol.
- 2016 Feb;54(1):31-38.
- doi: 10.3347/kjp.2016.54.1.31
Specific gene expressions of host cells by spontaneous STAT6 phosphorylation are major strategy for the survival of intracellular Toxoplasma gondii against parasiticidal events through STAT1 phosphorylation by infection provoked IFN-γ.... -
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- STAT6 Expression and IL-13 Production in Association with Goblet Cell Hyperplasia and Worm Expulsion of Gymnophalloides seoi from C57BL/6 Mice
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Lee JJ, Kim D, Pyo KH, Kim MK, Kim HJ, Chai JY, Shin EH
- KMID: 1792154
- Korean J Parasitol.
- 2013 Oct;51(5):589-594.
In intestinal helminth infections, Th2 immune respones are generally associated with mucin secretion for worm expulsion from the host intestine. In particular, IL-4 and IL-13 are the important cytokines related... -
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- Anti-Apoptotic Effects of SERPIN B3 and B4 via STAT6 Activation in Macrophages after Infection with Toxoplasma gondii
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Song KJ, Ahn HJ, Nam HW
- KMID: 1364888
- Korean J Parasitol.
- 2012 Mar;50(1):1-6.
- doi: 10.3347/kjp.2012.50.1.1
Toxoplasma gondii penetrates all kinds of nucleated eukaryotic cells but modulates host cells differently for its intracellular survival. In a previous study, we found out that serine protease inhibitors B3... -
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- Frozen Cytology of Meningeal Malignant Solitary Fibrous Tumor/Hemangiopericytoma
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Kang M, Kim NR, Chung DH, Yie GT
- KMID: 2449343
- J Pathol Transl Med.
- 2019 May;53(3):192-197.
- doi: 10.4132/jptm.2019.03.20
A 51-year-old woman presented with severe dizziness. The brain magnetic resonance image revealed a 5.5 cm multiloculated mass with a thick rim in the left temporal lobe. Cytological examination of... -
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- Effects of Scutellarin on MUC5AC Mucin Production Induced by Human Neutrophil Elastase or Interleukin 13 on Airway Epithelial Cells
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Jiang DP, Perelman J, Kolosov VP, Zhou XD
- KMID: 1785964
- J Korean Med Sci.
- 2011 Jun;26(6):778-784.
- doi: 10.3346/jkms.2011.26.6.778
Scutellarin is a flavonoid extracted from a traditional Chinese herb, Erigeron breviscapus. The present study investigated the effect of scutellarin on MUC5AC mucin production and the possible mechanism. Human bronchial... -
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