- Anti-inflammatory Activity of Fucoidan with Blocking NF-kappaB and STAT1 in Human Keratinocytes Cells
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Ryu MJ, Chung HS
- KMID: 2312897
- Nat Prod Sci.
- 2015 Sep;21(3):205-209.
- doi: 10.0000/nps.2015.21.3.205
Fucoidan, a sulfated polysaccharide is found in several types of edible brown algae. It has shown numerous biological activities; however, the molecular mechanisms on the activity against atopic dermatitis have... -
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- Bronchiectasis and Recurrent Respiratory Infections with a De Novo STAT1 Gain-of-Function Variant: First Case in Korea
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Huh HJ, Jhun BW, Choi SR, Kim YJ, Yun SA, Nham E, Kong T, Ki CS, Koh WJ
- KMID: 2419736
- Yonsei Med J.
- 2018 Oct;59(8):1004-1007.
- doi: 10.3349/ymj.2018.59.8.1004
Bronchiectasis is a chronic disease characterized by airway infection and inflammation, leading to permanent dilation of the bronchi. Evaluation of underlying etiology is important in managing young bronchiectasis patients with... -
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- Effect of quercetin on the production of nitric oxide in murine macrophages stimulated with lipopolysaccharide from Prevotella intermedia
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Cho YJ, Kim SJ
- KMID: 2027815
- J Periodontal Implant Sci.
- 2013 Aug;43(4):191-197.
- doi: 10.5051/jpis.2013.43.4.191
PURPOSE: Nitric oxide (NO) is a short-lived bioactive molecule that is known to play an important role in the pathogenesis of periodontal disease. In the current study, we investigated the... -
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- Interferon-free treatment for hepatitis C virus infection induces normalization of extrahepatic type I interferon signaling
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Sung PS, Lee EB, Park DJ, Lozada A, Jang JW, Bae SH, Choi JY, Yoon SK
- KMID: 2428758
- Clin Mol Hepatol.
- 2018 Sep;24(3):302-310.
- doi: 10.3350/cmh.2017.0074
BACKGROUND/AIMS: Hepatitis C virus (HCV) replicates in the peripheral blood mononuclear cells (PBMCs), leading to the production of type I interferons (IFNs). It is well known that the gene expression... -
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- Gene Expression Profile Analysis of Human Breast Cancer Using cDNA Microarrys
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Kim HS, Jung JH, Park HY, Lee YH, Chung EJ, Kim MK, Kim JC
- KMID: 2006608
- J Korean Breast Cancer Soc.
- 2003 Jun;6(2):58-67.
- doi: 10.4048/jkbcs.2003.6.2.58
PURPOSE: The aim of this study was to classify breast carcinomas based on variations in gene expression patterns derived from cDNA microarrays and to correlate tumor characteristics to clinical outcome.... -
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- Benzylideneacetophenone derivatives attenuate IFN-gamma-induced IP-10/CXCL10 production in orbital fibroblasts of patients with thyroid-associated ophthalmopathy through STAT-1 inhibition
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Lee SH, Lim SY, Choi JH, Jung JC, Oh S, Kook KH, Choi YH
- KMID: 2155365
- Exp Mol Med.
- 2014 Jun;46(6):e100.
- doi: 10.1038/emm.2014.26
The aim of the present study was to identify a new candidate anti-inflammatory compound for use in the active stage of thyroid-associated ophthalmopathy (TAO). Benzylideneacetophenone compound JC3 [(2E)-3-(4-hydroxy-3-methoxyphenyl)phenylpro-2-en-l-one] was synthesized... -
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