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Inhibitory effect of Mg2+ on the release of Ca2+ from Ryanodine receptor of the sarcoplasmic reticulum in the skeletal muscle

Lee CJ

  • KMID: 1686430
  • Korean J Thorac Cardiovasc Surg.
  • 1992 Apr;25(4):347-355.
No abstract available.
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Thyroid hormone-induced alterations of ryanodine and dihydropyridine receptor protein expression in rat hear

Kim HW, Park M, Lee EH, Cho HJ, Lee HR

  • KMID: 2285227
  • Korean J Physiol Pharmacol.
  • 1999 Jun;3(3):329-337.
Thyroid hormone-induced cellular dysfunctions may be associated with changes in the intracellular Ca2+ concentration. The ryanodine receptor, a Ca2+ release channel of the SR, is responsible for the rapid release of Ca2+ that...
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(3H)Ryanodine binding sites of SR vesicles of the chicken pectoral muscle

Yun HY, Jeon JR, Hong JH, Hur GM, Lee JH, Seok JH

  • KMID: 2071509
  • Korean J Physiol Pharmacol.
  • 1997 Aug;1(4):377-384.
To investigate the properties of ryanodine binding sites of the bird skeletal SR vesicles, SDS PAGE, purification of RyR, and (3H)ryanodine binding study were carried out in the SR vesicles prepared from...
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Effects of ryanodine on the intracellular Na+ activity and tension and action potentials of rat and guinea pig cardiac ventricular muscles

Suh CK, Park SR

Ryanodine has different effects on the contractility of rat and guinea pig ventricular muscle. Thus we investigated the effect of ryanodine on the intracellular Ca2+ and Na+ activities of the...
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Effect of IP3 and ryanodine treatments on the development of bovine parthenogenetic and reconstructed embryos

Ahn GJ, Lee BC, Hwang WS

  • KMID: 1103521
  • J Vet Sci.
  • 2001 Aug;2(2):131-137.
For parthenogenetic activation as a model system of nuclear transfer, microinjection and electroporation as activation treatments in bovine metaphase II oocytes were administered to each of three groups as follows:...
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Na+-Ca2+ Exchange Curtails Ca2+ before Its Diffusion to Global Ca2+i in the Rat Ventricular Myocyte

Ahn SW, Ko CM

  • KMID: 2285315
  • Korean J Physiol Pharmacol.
  • 2005 Apr;9(2):95-101.
In the heart, Na+-Ca2+ exchange (NCX) is the major Ca2+ extrusion mechanism. NCX has been considered as a relaxation mechanism, as it reduces global [Ca2+]i raised during activation. However, if...
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Unchanged protein level of ryanodine receptor but reduced (3H) ryanodine binding of cardiac sarcoplasmic reticulum from diabetic cardiomyopathy rats

Lee EH, Seo YJ, Kim YH, Kim HW

  • KMID: 1607079
  • Korean J Physiol Pharmacol.
  • 2001 Oct;5(5):397-405.
The ryanodine receptor, a Ca2+ release channel of the sarcoplasmic reticulum (SR), is responsible for the rapid release of Ca2+ that activates cardiac muscle contraction. In the excitation-contraction coupling cascade, activation of SR...
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Ryanodine Receptor-mediated Calcium Release Regulates Neuronal Excitability in Rat Spinal Substantia Gelatinosa Neurons

Park A, Chun SW

Nitric Oxide (NO) is an important signaling molecule in the nociceptive process. Our previous study suggested that high concentrations of sodium nitroprusside (SNP), a NO donor, induce a membrane hyperpolarization...
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Changes in the Expressional Levels of Sarcoplasmic Reticulum Ca2+-regulatory Proteins in the Postnatal Developing Rat Heart

Lee EH, Park SS, Lee JS, Seo YJ, Kim YH, Kim HW

  • KMID: 1614999
  • Korean J Physiol Pharmacol.
  • 2002 Apr;6(2):101-108.
In the present study, the postnatal developmental changes in the expressional levels of cardiac sarcoplasmic reticulum (SR) Ca2+ regulatory proteins, i.e. Ca2+-ATPase, phospholamban, and Ca2+ release channel, were investigated. Both...
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Ca2+-induced Ca2+ Release from Sarcoplasmic Reticulum Negatively Regulates Myocytic ANP Release in Beating Rabbit Atria

Li D, Quan HX, Wen JF, Jin JY, Park SH, Kim SY, Kim SZ, Cho KW

  • KMID: 2285314
  • Korean J Physiol Pharmacol.
  • 2005 Apr;9(2):87-94.
It is not clear whether Ca2+-induced Ca2+ release from the sarcoplasmic reticulum (SR) is involved in the regulation of atrial natriuretic peptide (ANP) release. Previously, we have shown that nifedipine...
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Alteration of Ryanodine-receptors in Cultured Rat Aortic Smooth Muscle Cells

Kim EJ, Kim DK, Kim SH, Lee KM, Park HS, Kim SH

Vascular smooth muscle cells can obtain a proliferative function in environments such as atherosclerosis in vivo or primary culture in vitro. Proliferation of vascular smooth muscle cells is accompanied by...
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Characteristics of Ca2+ stores in rabbit cerebral artery myocytes

Kim SJ, Kim JK, So I, Suh SH, Lee SJ, Kim KW

  • KMID: 1849839
  • Korean J Physiol Pharmacol.
  • 1998 Jun;2(3):313-322.
In a myocyte freshly isolated from rabbit cerebral artery, the characteristics of Ca2+ release by histamine or caffeine were studied by microspectrofluorimetry using a Ca2+-binding fluorescent dye, fura-2. Histamine (5 micrometer) or caffeine...
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Caffeine causes glycerophosphorylcholine accumulation through ryanodine-inhibitable increase of cellular calcium and activation of phospholipase A2 in cultured MDCK cells

Kim DK, Jung KY

  • KMID: 1109298
  • Exp Mol Med.
  • 1998 Sep;30(3):151-158.
Glycerophosphrylocholine (GPC) is a renal medullary compatible organic osmolyte that is derived from choline via phosphatidylcholine, which is catalyzed in part by phospholipase A2 (PLA2) and its degradation by GPC: choline phosphodiesterase (GPC:...
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Ca(2+)-induced Ca2+ Release from Internal Stores in INS-1 Rat Insulinoma Cells

Choi KJ, Cho DS, Kim JY, Kim BJ, Lee KM, Kim SH, Kim DK, Kim SH, Park HS

  • KMID: 2389109
  • Korean J Physiol Pharmacol.
  • 2011 Feb;15(1):53-59.
The secretion of insulin from pancreatic beta-cells is triggered by the influx of Ca2+ through voltage-dependent Ca2+ channels. The resulting elevation of intracellular calcium ([Ca2+]i) triggers additional Ca2+ release from...
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A Double Mutation of the Ryanodine Receptor Type 1 Gene in a Malignant Hyperthermia Family with Multiminicore Myopathy

Jeong SK, Kim DC, Cho YG, Sunwo IN, Kim DS

BACKGROUND AND PURPOSE: At least 100 Ryanodine receptor type 1 (RYR1) mutations associated with malignant hyperthermia (MH) and central core disease (CCD) have been identified, but 2 RYR1 mutations accompanying...
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Delayed Onset of Malignant Hyperthermia: A Case Report

Lim JW, Yeo SK, Yang SH, Hwang IS, Lee JS

Malignant hyperthermia is a potentially fatal genetic and metabolic myopathy that presents with high fever, and muscle rigidity, and it often occurs after administering anesthetic medication. Most cases of malignant...
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Effects of Na-Ca Exchange Mechanism on the Action Potential and Membrane Currents in the Single Cells of the Guinea-Pig and the Rabbit Heart

Kim JH, Lim HK, Lee BH, Lee CK, Earm YE

In single atrial and ventricular cells isolated from the guinea-pig and the rabbit heart, action potentials and membrane currents were recorded by using the whole cell voltage clamp technique. In...
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Effect of Ketamine on Phenylephrine-Induced Contraction in Isolated Rat Thoracic Aorta

Ok SH, Sohn JT, Lee JH, Park MY, Shin IW, Lee HK, Chung YK

BACKGROUND: Ketamine causes a dose-dependent vasodilation of a norepinephrine-precontracted pulmonary arterial ring. The goals of the present in vitro study were to investigate the effects of ketamine on phenylephrine-induced contraction...
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Calcium Uptake and Release through Sarcoplasmic Reticulum in the Inferior Oblique Muscles of Patients with Inferior Oblique Overaction

Kim HS, Chang YH, Kim DH, Park SR, Han SH, Lee JB

We characterized and compared the characteristics of Ca2+ movements through the sarcoplasmic reticulum of inferior oblique muscles in the various conditions including primary inferior oblique overaction (IOOA), secondary IOOA, and...
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The effect of Ni2+ on the intracellular Ca2+ increase of the mouse early 2-cell embryos

Yoon SY, Lee EM, Bae IH

  • KMID: 2304560
  • Korean J Fertil Steril.
  • 2003 Dec;30(4):269-280.
OBJECTIVE: We reported the overcoming effect of Ni2+ on the in vitro 2-cell block of mouse embryos. In this study, we aim to investigate whether Ni2+ should induce intracellular Ca2+...
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