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Shank 2 expression coincides with neuronal differentiation in the developing retina

Kim JH, Kim JH, Yang E, Park JH, Yu YS, Kim KW

The retinal activity for vision requires a precise synaptic connectivity. Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. However, the correlation...
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Indoleamine-accumulating cell death and endogenous glial cell reaction induced by 5,7-dihydroxytryptamine in the cat retina

Jo SM, Nam SA, Yoon SS, Ko BM, Choi CD, Choi WB, Chun MH

We investigated the patterns of degenerative changes of indoleamine-accumulating cells (IACs) induced by 5,7-dihydroxytryptamine (5,7-DHT, 100 microg), and the glial reaction to the neurodegenerative changes of IACs in the...
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The electroretinographic change by the acute effects of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Kim DM, Lee J

The electrophysiological effects of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (NMPTP), a chemical inducer of Parkinsonism in man and monkey, on the pigmented rabbit retina were determined under acute conditions. The amplitude of the b-wave...
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Intravenously Administered Anti-recoverin Antibody Alone Does Not Pass through the Blood-Retinal Barrier

Kim JH, Kim JH, Kim DH, Park WY, Kim KW, Yu YS

PURPOSE: Cancer-associated retinopathy is a paraneoplastic retinal degeneration which may primarily result from auto-immune mediated apoptosis. It has been hypothesized that high titer of auto-antibodies are able to cross the...
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Methylglyoxal Induces Apoptosis Mediated by Reactive Oxygen Species in Bovine Retinal Pericytes

Kim J, Son JW, Lee JA, Oh YS, Shinn SH

One of the histopathologic hallmarks of early diabetic retinopathy is the loss of pericytes. Evidences suggest that the pericyte loss in vivo is mediated by apoptosis. However, the underlying cause...
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Effect of Amiloride to Retinal Toxicity Induced by Tissue Plasminogen Activator

Kim US, Oh HS, Kwon OW, Chung I, Lee SH, Lee JH

PURPOSE: The effects of amiloride on cellular toxicity caused by tissue plasminogen activator (tPA) in mouse primary retinal cells were investigated. METHODS: Primary retinal cell cultures were maintained using glial conditioned...
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