- SP600125, a selective JNK inhibitor, aggravates hepatic ischemia-reperfusion injury
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Lee KH, Kim SE, Lee YS
- KMID: 1110125
- Exp Mol Med.
- 2006 Aug;38(4):408-416.
c-Jun N-terminal kinase (JNK) is activated during hepatic reperfusion, and JNK inhibitors are known to protect other major organs from ischemia-reperfusion (I/R) injury. We attempted to determine the effect of... -
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- Effects of sevoflurane on tight junction protein expression and PKC-alpha translocation after pulmonary ischemia-reperfusion injury
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Chai J, Long B, Liu X, Li Y, Han N, Zhao P, Chen W
- KMID: 2155421
- Exp Mol Med.
- 2015 Jun;47(6):e167.
- doi: 10.1038/emm.2015.27
Pulmonary dysfunction caused by ischemia-reperfusion injury is the leading cause of mortality in lung transplantation. We aimed to investigate the effects of sevoflurane pretreatment on lung permeability, tight junction protein... -
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- Myocardial Protective Effect of Tezosentan, an Endothelin Receptor Antagonist, for Ischemia-Reperfusion Injury in Experimental Heart Failure Models
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Ryu SM, Kim HJ, Cho KR, Jo WM
- KMID: 1781994
- J Korean Med Sci.
- 2009 Oct;24(5):782-788.
- doi: 10.3346/jkms.2009.24.5.782
The myocardial protective effects of endothelin antagonist in ischemic cardiomyopathy (ICMP), doxorubicin-induced cardiomyopathy (DOX) and pressure-overload hypertrophy by transverse aortic constriction (TAC) models have been predicted to be different. The... -
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- Ethyl Pyruvate Has Anti-Inflammatory and Delayed Myocardial Protective Effects after Regional Ischemia/Reperfusion Injury
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Jang IS, Park MY, Shin IW, Sohn JT, Lee HK, Chung YK
- KMID: 1779628
- Yonsei Med J.
- 2010 Nov;51(6):838-844.
- doi: 10.3349/ymj.2010.51.6.838
PURPOSE: Ethyl pyruvate has anti-inflammatory properties and protects organs from ischemia/reperfusion (I/R)-induced tissue injury. The aim of this study was to determine whether ethyl pyruvate decreases the inflammatory response after... -
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- The Effect of High Dose Melatonin on Cardiac Ischemia-reperfusion Injury
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Ceyran H, Narin F, Narin N, Akgun H, Ceyran AB, Ozturk F, Akcali Y
- KMID: 2158191
- Yonsei Med J.
- 2008 Oct;49(5):735-741.
- doi: 10.3349/ymj.2008.49.5.735
PURPOSE: Melatonin, the most potent scavenger of toxic free radicals, has been found to be effective in protecting against pathological states due to the release of reactive oxygen species. This... -
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- SPA0355 attenuates ischemia/reperfusion-induced liver injury in mice
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Bae UJ, Yang JD, Ka SO, Koo JH, Woo SJ, Lee YR, Yu HC, Cho BH, Zhao HY, Ryu JH, Lee SM, Jeon R, Park BH
- KMID: 2155374
- Exp Mol Med.
- 2014 Aug;46(8):e109.
- doi: 10.1038/emm.2014.48
Hepatic ischemia/reperfusion (I/R) injury leads to oxidative stress and acute inflammatory responses that cause liver damage and have a considerable impact on the postoperative outcome. Much research has been performed... -
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- Effects of alpha-Phenyl-N-tert-Butyl Nitrone (PBN)on Brain Cell Membrane Function and Energy Metabolism during Transient Global Cerebral Hypoxia-Ischemia and Reoxygenation-Reperfusion in Newborn Piglets
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Choi CW, Hwang JH, Chang YS, Shin SM, Park WS, Lee M
- KMID: 1786821
- J Korean Med Sci.
- 2004 Jun;19(3):413-418.
- doi: 10.3346/jkms.2004.19.3.413
We sought to know whether a free radical spin trap agent, alpha-phenyl-N-tert-butyl nitrone (PBN) influences brain cell membrane function and energy metabolism during and after transient global hypoxia-ischemia (HI) in... -
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