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Scavenger Receptor Class A to E Involved in Various Cancers

Ryu S, Howland A, Song B, Youn C, Song PI

Scavenger receptors typically bind to multiple ligands on a cell surface, including endogenous and modified host-derived molecules and microbial pathogens. They promote the elimination of degraded or harmful substances such...
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Metformin Down-regulates TNF-alpha Secretion via Suppression of Scavenger Receptors in Macrophages

Hyun B, Shin S, Lee A, Lee S, Song Y, Ha NJ, Cho KH, Kim K

Obesity is consistently increasing in prevalence and can trigger insulin resistance and type 2 diabetes. Many lines of evidence have shown that macrophages play a major role in inflammation associated...
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The in vivo and in vitro Roles of Epithelial Pattern Recognition Receptors in Pneumococcal Infections

Shin SG, Koh SH, Lim JH

Streptococcus pneumoniae, also called pneumococcus, is a major cause of infectious disease in human. Pneumococcus resides in the nasopharynx as an upper respiratory commensal, and most of pneumococcal colonizations are...
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Transporters and Nuclear Hormone Receptors associated with Cholesterol Metabolism in Gallbladder Epithelial Cells

Lee J

  • KMID: 2168079
  • Hanyang Med Rev.
  • 2007 Feb;27(1):20-28.
Bile is concentrated in the gallbladder, and is often supersaturated in terms of cholesterol concentration. Such high levels of cholesterol in gallbladder bile has clinical implications with respect to cholesterol...
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The Effect of LDL Oxidation Caused an Atherosclerosis in Macrophage Cells * : The Antioxidant Effect of Ganhaungenin

Her E, Lee ST, Cho SI, Park DK

  • KMID: 2082999
  • Korean J Immunol.
  • 1997 Sep;19(3):337-346.
Oxidatively modified low density lipoprotein (LDL) could contribute to one of the atherosclerotic processes through its uptake by the scavenger receptor of macrophage. The aim of the present study was...
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Topology of Scavenger Receptor Class B Type I (SR-BI) on Brush Border Membrane

Han CH, Lee MH

  • KMID: 1097342
  • J Vet Sci.
  • 2002 Dec;3(4):265-272.
Both hydropathy plot and in vitro translation results predict the topology of SR-BI; the receptor is an integral membrane protein of 509 amino acids, consisting of a short cytoplasmic N-terminus...
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Comparison of serum lipid profiles and total antioxidant status in vegetarian and non-vegetarian groups

Kim SG, Kim HI, Yum MS, Jo H, O YY, Kwan HJ, Cho WH, Park JS

  • KMID: 2306236
  • Korean J Med.
  • 2000 Feb;58(2):197-203.
BACKGROUND: Previous studies have demonstrated that modified or oxidized lipoproteins play a key role in the process of atherogenesis, particularly in hyperlipidemic individuals. Low density lipoprotein(LDL) is modified by oxygen...
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Introduction of a Model for Study of Polarized Cholesterol and Phospholipid Efflux in Gallbladder Epithelial Cell

Lee J

  • KMID: 1864976
  • Korean J Gastroenterol.
  • 2002 Mar;39(3):216-225.
BACKGROUND/AIMS: The cholesterol absorption by gallbladder epithelial cell (GBEC) is well known. However, the metabolism of the absorbed cholesterol in GBEC is not established yet. Thus, in this study, I...
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CD36 (SR-B2) as a Target to Treat Lipid Overload-Induced Cardiac Dysfunction

Glatz JF, Luiken JJ, Nabben M

The heart faces the challenge of adjusting the rate of fatty acid uptake to match myocardial demand for energy provision at any given moment, avoiding both too low uptake rates,...
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Enterovirus 71 infection and neurological complications

Lee KY

Since the outbreak of the enterovirus 71 (EV71) infection in Malaysia in 1997, large epidemics of EV71 have occurred in the Asia-Pacific region. Many children and infants have died from...
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Effect of combined mulberry leaf and fruit extract on liver and skin cholesterol transporters in high fat diet-induced obese mice

Valacchi G, Belmonte G, Miracco C, Eo H, Lim Y

  • KMID: 2313706
  • Nutr Res Pract.
  • 2014 Feb;8(1):20-26.
Obesity is an epidemic disease characterized by an increased inflammatory state and chronic oxidative stress with high levels of pro-inflammatory cytokines and lipid peroxidation. Moreover, obesity alters cholesterol metabolism with...
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Dietary Aloe Reduces Adipogenesis via the Activation of AMPK and Suppresses Obesity-related Inflammation in Obese Mice

Shin E, Shin S, Kong H, Lee S, Do SG, Jo TH, Park YI, Lee CK, Hwang IK, Kim K

BACKGROUND: Metabolic disorders, including type II diabetes and obesity, present major health risks in industrialized countries. AMP-activated protein kinase (AMPK) has become the focus of a great deal of attention...
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Dietary Aloe QDM Complex Reduces Obesity-Induced Insulin Resistance and Adipogenesis in Obese Mice Fed a High-Fat Diet

Shin S, Kim S, Oh HE, Kong H, Shin E, Do SG, Jo TH, Park YI, Lee CK, Kim K

Obesity-induced disorders contribute to the development of metabolic diseases such as insulin resistance, fatty liver diseases, and type 2 diabetes (T2D). In this study, we evaluated whether the Aloe QDM...
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Prognostic Implications of the Expression of CXCL16 in Breast Carcinoma

Choi DY, Hong R, Lim SC, Kee KH, Suh CH, Lee M

  • KMID: 2277515
  • Korean J Pathol.
  • 2011 Feb;45(1):15-20.
BACKGROUND: Of the many prognostic factors for breast cancer, the relationship between an infiltration of inflammatory cells and the prognosis is debatable. Of the chemokines affecting cancer's inflammatory reactions, chemokine...
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