- Promising Pharmacological Directions in the World of Lysophosphatidic Acid Signaling
-
Stoddard N, Chun J
- KMID: 2380356
- Biomol Ther.
- 2015 Jan;23(1):1-11.
- doi: 10.4062/biomolther.2014.109
Lysophosphatidic acid (LPA) is a signaling lipid that binds to six known lysophosphatidic acid receptors (LPARs), named LPA1-LPA6. These receptors initiate signaling cascades relevant to development, maintenance, and healing processes... -
- CITED
-
- Close
- SHARE
-
- Close
- Lysophosphatidic acid enhances breast cancer cells-mediated osteoclastogenesis
-
Nam JS, Sharma AR, Nguyen LT, Jagga S, Lee YH, Sharma G, Lee SS
- KMID: 2419000
- Korean J Physiol Pharmacol.
- 2018 Sep;22(5):503-511.
- doi: 10.4196/kjpp.2018.22.5.503
Lysophosphatidic acid (LPA) is known to play a critical role in breast cancer metastasis to bone. In this study, we tried to investigate any role of LPA in the regulation... -
- CITED
-
- Close
- SHARE
-
- Close
- Role of TAZ in Lysophosphatidic Acid-Induced Migration and Proliferation of Human Adipose-Derived Mesenchymal Stem Cells
-
Mo WM, Kwon YW, Jang IH, Choi EJ, Kwon SM, Kim JH
- KMID: 2386900
- Biomol Ther.
- 2017 Jul;25(4):354-361.
- doi: 10.4062/biomolther.2016.263
Transcriptional co-activator with a PDZ-binding motif (TAZ) is an important factor in lysophosphatidic acid (LPA)-induced promotion of migration and proliferation of human mesenchymal stem cells (MSCs). The expression of TAZ... -
- CITED
-
- Close
- SHARE
-
- Close
- Activation of Lysophosphatidic Acid Receptor Is Coupled to Enhancement of Ca(2+)-Activated Potassium Channel Currents
-
Choi SH, Lee BH, Kim HJ, Hwang SH, Lee SM, Nah SY
- KMID: 1429302
- Korean J Physiol Pharmacol.
- 2013 Jun;17(3):223-228.
- doi: 10.4196/kjpp.2013.17.3.223
The calcium-activated K+ (BKCa) channel is one of the potassium-selective ion channels that are present in the nervous and vascular systems. Ca2+ is the main regulator of BKCa channel activation.... -
- CITED
-
- Close
- SHARE
-
- Close
- Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells
-
Jeong KJ, Park SY, Seo JH, Lee KB, Choi WS, Han JW, Kang JK, Park CG, Kim YK, Lee HY
- KMID: 1072941
- Exp Mol Med.
- 2008 Dec;40(6):607-616.
- doi: 10.3858/emm.2008.40.6.607
Lysophosphatidic acid (LPA) is a bioactive phospholipids and involves in various cellular events, including tumor cell migration. In the present study, we investigated LPA receptor and its transactivation to EGFR... -
- CITED
-
- Close
- SHARE
-
- Close
- Role of LPA and the Hippo pathway on apoptosis in salivary gland epithelial cells
-
Hwang SM, Jin M, Shin YH, Ki Choi S, Namkoong E, Kim M, Park MY, Park K
- KMID: 2155390
- Exp Mol Med.
- 2014 Dec;46(12):e125.
- doi: 10.1038/emm.2014.77
Lysophosphatidic acid (LPA) is a bioactive lysophospholipid involved in numerous physiological responses. However, the expression of LPA receptors and the role of the Hippo signaling pathway in epithelial cells have... -
- CITED
-
- Close
- SHARE
-
- Close
- Gintonin, an exogenous ginseng-derived LPA receptor ligand, promotes corneal wound healing
-
Kim HJ, Kim JY, Lee BH, Choi SH, Rhim H, Kim HC, Ahn SY, Jeong SW, Jang M, Cho IH, Nah SY
- KMID: 2412457
- J Vet Sci.
- 2017 Sep;18(3):387-397.
- doi: 10.4142/jvs.2017.18.3.387
Ginseng gintonin is an exogenous ligand of lysophosphatidic acid (LPA) receptors. Accumulating evidence shows LPA helps in rapid recovery of corneal damage. The aim of this study was to evaluate... -
- CITED
-
- Close
- SHARE
-
- Close
- Signaling Pathway of Lysophosphatidic Acid-Induced Contraction in Feline Esophageal Smooth Muscle Cells
-
Nam YS, Suh JS, Song HJ, Sohn UD
- KMID: 1429385
- Korean J Physiol Pharmacol.
- 2013 Apr;17(2):139-147.
- doi: 10.4196/kjpp.2013.17.2.139
Lysolipids such as LPA, S1P and SPC have diverse biological activities including cell proliferation, differentiation, and migration. We investigated signaling pathways of LPA-induced contraction in feline esophageal smooth muscle cells.... -
- CITED
-
- Close
- SHARE
-
- Close
- Synovial fluid of patients with rheumatoid arthritis induces alpha-smooth muscle actin in human adipose tissue-derived mesenchymal stem cells through a TGF-beta1-dependent mechanism
-
Song HY, Kim MY, Kim KH, Lee IH, Shin SH, Lee JS, Kim JH
- KMID: 1104383
- Exp Mol Med.
- 2010 Aug;42(8):565-573.
- doi: 10.3858/emm.2010.42.8.057
Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints. Transforming growth factor-beta1 (TGF-beta1) is a secreted protein that promotes differentiation of... -
- CITED
-
- Close
- SHARE
-
- Close
