- Genes Involved in Interleukin-1 Receptor Type II Activities Are Associated With Asthmatic Phenotypes
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Madore AM, Vaillancourt VT, Bouzigon E, Sarnowski , Monier F, Dizier MH, Demenais F, Laprise C
- KMID: 2295157
- Allergy Asthma Immunol Res.
- 2016 Sep;8(5):466-470.
- doi: 10.4168/aair.2016.8.5.466
PURPOSE: Interleukin-1 (IL-1) plays a key role in inflammation and immunity and its decoy receptor, IL-1R2, has been implicated in transcriptomic and genetic studies of asthma. METHODS: Two large asthma family... -
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- Interleukin 1 Receptor Antagonist(IL-1ra) Gene Polymorphism in Children with Henoch-Schonlein Purpura Nephritis
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Hwang PK, Lee JN, Chung WY
- KMID: 1627742
- J Korean Soc Pediatr Nephrol.
- 2005 Oct;9(2):175-182.
PURPOSE: Interleukin 1 receptor antagonist(IL-1ra) is an endogenous antiinflammatory agent that binds to IL-1 receptor and thus competitively inhibits the binding of IL-1alpha and IL-1beta. Allele 2 in association with... -
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- Synergy between adiponectin and interleukin-1beta on the expression of interleukin-6, interleukin-8, and cyclooxygenase-2 in fibroblast-like synoviocytes
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Lee YA, Choi HM, Lee SH, Yang HI, Yoo MC, Hong SJ, Kim KS
- KMID: 1397448
- Exp Mol Med.
- 2012 Jul;44(7):440-447.
To determine whether adiponectin may have synergistic effects in combination with the proinflammatory cytokine interleukin (IL)-1beta regarding the production of proinflammatory mediators during arthritic joint inflammation, synovial cells from rheumatoid... -
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- Age-related regional difference of interleukin-1 expression in rat brain after lipopolysaccharide treatment
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Huh GY, Roh MS, Bae HR
- KMID: 1066502
- J Korean Med Sci.
- 2001 Feb;16(1):103-107.
- doi: 10.3346/jkms.2001.16.1.103
Aging is associated with altered immune responses including dysregulation of cytokine production. Of cytokines, interleukin-1 (IL-1) family has been primarily involved with central nervous system. To evaluate the age-related different... -
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- Toll-like receptor signal transduction
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Krishnan J, Selvarajoo K, Tsuchiya M, Lee G, Choi S
- KMID: 756065
- Exp Mol Med.
- 2007 Aug;39(4):421-438.
Toll-like receptors (TLRs) are the archetypal pattern recognition receptors in sensing exogenous pathogens. Activation of TLRs is a first line of defense of the immune system, leading to the activation... -
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- Association of a genetic polymorphism of IL1RN with risk of acute pancreatitis in a Korean ethnic group
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Park JW, Choi JS, Han KJ, Lee SH, Kim EJ, Cho JH
- KMID: 2426394
- Korean J Intern Med.
- 2018 Nov;33(6):1103-1110.
- doi: 10.3904/kjim.2017.133
BACKGROUND/AIMS: Several epidemiological studies have validated the association of interleukin gene polymorphisms with acute pancreatitis (AP) in different populations. However, there have been few studies in Asian ethnic groups. We... -
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- Changes of Plasma Interleukin-1 Receptor Antagonist, Interleukin-8 and other Serologic Markers during Chemotherapy in Patients with Active Pulmonary Tuberculosis
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Lee JH, Chang JH
- KMID: 759652
- Korean J Intern Med.
- 2003 Sep;18(3):138-145.
BACKGROUND: The human immune response to Mycobacterium tuberculosis is mediated by macrophages and T-lymphocytes. The alveolar macrophage phagocyting mycobacterium produces interleukin (IL) -1 as an inflammatory mediator, and IL-8 as... -
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