- Significance of EGFR and c-erbB-2 Expression in Extrahepatic Bile Duct Cancer
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Son GS, Choi SY, Suh SO, Kim YC
- KMID: 1928539
- Korean J Hepatobiliary Pancreat Surg.
- 1998 Feb;2(1):95-102.
Until now, surgical treatment of bile duct carcinoma has been unsatisfactory. There have been few reports dealing with the clinical significance of epidermal growth factor receptor(EGFR) and c-erbB-2 in bile... -
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- Overexpression of hTERT and c-erbB-2 are correlated in ovarian epithelial cancer
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Kang S, Park NH, Lee YK, Kim JW, Song YS, Kang SB, Lee HP
- KMID: 2244587
- Korean J Gynecol Oncol.
- 2006 Jun;17(2):142-146.
OBJECTIVE: It is still unclear how the abnormal hTERT expression is involved in the process of ovarian carcinogenesis. A recent report demonstrated that the introduction of c-erbB-2 could efficiently induce... -
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- Detection of C-erbB-2 Internal Domain in Bladder Tumor
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Kim WJ, Lee HM, Song HG
- KMID: 2060528
- Korean J Urol.
- 1994 Oct;35(10):1041-1046.
c-erbB-2 overexpression appears to play a role in determining the malignant potential of some human cancers. Using a specific monoclonal antibody to c-erbB-2 internal domain, 25 transitional cell carcinoma and... -
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- Immunohistochemical Expression of c-erbB-2 Protein in Breast Cancer
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Kim BN, Park HY, Lee YH, Park JY, Son YK
- KMID: 2209461
- J Korean Surg Soc.
- 2002 Jun;62(6):456-462.
PURPOSE: A clinical trial that evaluated the efficacy of Herceptin(R) (anti-erbB2 antibody) as a first-line therapy for metastatic breast cancer was presented. It was demonstrated that 38% of the metastatic... -
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- The Expression of p53, c-erbB-2 and nm23 Proteins in Breast Cancer
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Lee KY, Kim YG, Kim YS, Han KJ, Kang CS, Kim JA, Kim WI, Shim SI
- KMID: 1921777
- Korean J Pathol.
- 1999 Feb;33(2):88-95.
Recently, p53, c-erbB-2 and nm23 proteins have been studied in breast cancer. The expression of p53 protein indicates the mutation of p53 gene known as a tumor supressor gene, and... -
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- Sebaceous carcinoma of the eyelids: frequent expression of c-erbB-2 oncoprotein
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Cho KJ, Khang SK, Koh JS, Chung JH, Lee SS
- KMID: 965877
- J Korean Med Sci.
- 2000 Oct;15(5):545-550.
- doi: 10.3346/jkms.2000.15.5.545
Ocular sebaceous carcinoma (OSC) is an uncommon malignancy with a potential to recur and metastasize. Some characteristics of sebaceous carcinoma, such as female preponderance, shown in the present series during... -
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- Epidermal Growth Factor Receptor and c-erbB-2 Expressions in Biliary Tract Cancers
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Kim JS, Ahn WS, Kim KH, Choi CS, Yoon HK, Choi YK
- KMID: 1866372
- Korean J Hepatobiliary Pancreat Surg.
- 2006 Dec;10(4):13-18.
PURPOSE: The expressions of epidermal growth factor receptor (EGFR) and c-erbB-2 have been considered to be implicated in the genesis and progression of cholangiocarcinomas. However, their clinical roles and pathological... -
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- C-erbB-2 Protein Expression and Correlation in Sera and Tumors of Non-Small Cell Lung Cancer Patients
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Ryoo HM, Lee SY, Lee KH, Hyun MS, Kim MJ
- KMID: 2329196
- J Korean Cancer Assoc.
- 2000 Dec;32(6):1100-1108.
PURPOSE: We have examined the expression of c-erbB-2 oncogene in sera and tissues of non-small cell lung cancer patients. MATERIALS AND METHODS: Serum levels of c-erbB-2 protein were measured by an... -
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- Fascin-1 Protein Expression in Gastric Carcinoma
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Chae SW, Sohn JH
- KMID: 2277680
- Korean J Pathol.
- 2006 Apr;40(2):112-117.
BACKGROUND: Fascin-1 is a globular cross-linking and actin bundling protein that provides mechanical support to cellular protrusions and cell motility. The expression of fascin in epithelial neoplasms has been recently... -
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- Expression of c-erbB-2 and Cyclooxygenase-2 in Pancreatic Ductal Adenocarcinoma
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Choi HJ, Kim HJ, Yun SS, Choi JH
- KMID: 1521666
- Korean J Pathol.
- 2007 Jun;41(3):171-175.
Background : Carcinoma of the pancreas is a fatal malignant disease with limited therapeutic options. Cyclooxygenase-2 (COX-2) and c-erbB-2 are known to be involved in the carcinogenesis, differentiation and invasiveness... -
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- Prognostic Significance of Immunohistochemical Expression of EGFR and C-erbB-2 Oncoprotein in Curatively Resected Gastric Cancer
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Song HS, Do YR, Kim IH, Sohn SS, Kwon KY
- KMID: 2166138
- Cancer Res Treat.
- 2004 Aug;36(4):240-245.
PURPOSE: The purpose of this study was to investigate the prognostic significance of the expression of EGFR and C-erbB-2 gene products by immunohistochemical analysis for curatively resected gastric adenocarcinoma. MATERIALS... -
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- Human Epidermal Growth Factor Receptor 2-positive Mucinous Carcinoma with Signet Ring Cell Differentiation, Which Showed Complete Response after Neoadjuvant Chemotherapy
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Jang Y, Cho EY, Cho SY
- KMID: 2450126
- J Breast Cancer.
- 2019 Jun;22(2):336-340.
- doi: 10.4048/jbc.2019.22.e17
Mucinous carcinoma (MC) is a rare subtype of breast cancer, which is composed of tumor cells floating in the abundant extracellular mucin. This form of cancer is usually estrogen receptor/progesterone... -
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- Expression of c-erbB2 and p53 in Curatively Resected Gastric Cancer: Correlation with Clinicopathologic Features and Prognosis
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Hur H, Yi JM, Lee IK, Song KY, Kim W, Park CH, Jeon HM
- KMID: 1963580
- J Korean Surg Soc.
- 2011 Mar;80(3):172-181.
- doi: 10.4174/jkss.2011.80.3.172
PURPOSE: We investigated the correlation between expression of c-erbB-2 and p53 proteins and clinicopathologic features of gastric cancer to reveal prognostic factors. METHODS: 125 patient records under going curative resection for... -
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- Expression of c-erbB-2 Oncoprotein and DNA Topoisomerase II-alpha in Premalignant Lesions and Invasive Squamous Cell Carcinomas of the Uterine Cervix
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Shin SH, Koo HM, Kim JS, Mun HK, Lee JD, Kim SY, Han JH, Cho TI, Lee TJ
- KMID: 2270617
- Korean J Obstet Gynecol.
- 2002 Dec;45(12):2124-2129.
OBJECTIVE: The relationship was studied between expression of c-erbB-2 oncoprotein and topoisomerase II-alpha as proliferating marker in precancerous lesions and invasive squamous carcinomas of the uterine cervix. METHODS: Total 81 formalin-fixed,... -
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- Clinicopathologic Significance of p53 and c-erbB-2 Protein Expression in Breast Carcinoma
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Kim JK, Song YJ, Cho SI, Ryu DH, Yun HY, Sung RH
- KMID: 2173576
- J Korean Breast Cancer Soc.
- 2002 Mar;5(1):59-64.
- doi: 10.4048/jkbcs.2002.5.1.59
PURPOSE: Reliable prognostic factors, including clinicopathological parameters (Ed-alternatively, "Reliable clinicopathologic prognostic factors") such as tumor size, axillary lymph node involvement, histologic grade, menopausal patient status and steroid receptor status, are... -
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- Clinicopathologic Significance of p53 and c-erbB-2 Protein Expression in Breast Carcinoma
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Kim JK, Song YJ, Cho SI, Ryu DH, Yun HY, Sung RH
- KMID: 2209431
- J Korean Surg Soc.
- 2002 Apr;62(4):282-287.
PURPOSE: Reliable prognostic factors, including clinicopathological parameters (Ed-alternatively, "Reliable clinicopathologic prognostic factors") such as tumor size, axillary lymph node involvement, histologic grade, menopausal patient status and steroid receptor status, are... -
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- Type of Intestinal Metaplasia in the Surrounding Mucosa of Gastric Carcinoma and Expression of bcl-2, p53 and c-erbB-2 Prtein in Gastric Carcinoma
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Cho SC, Kwon KY
- KMID: 2059286
- J Korean Cancer Assoc.
- 1999 Oct;31(5):898-911.
PURPOSE: This study was carried out to clarify significance of types of intestinal metaplasia and roles of bcl-2, p53 and c-erbB-2 protein in the development of gastric carcinoma. MATERIALS AND METHODS:... -
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- Expression of p53 and c-erbB-2 Proteins as a Prognostic Factor in Patients with Gastric Carcinomas
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Jeong EJ, Ha WS, Park ST, Lee YJ, Jong JY, Cho YH, Lee YJ, Jeong MH
- KMID: 1940350
- J Korean Surg Soc.
- 1998 May;54(5):649-661.
Gastric cancer is not only one of the most common cancers in the world but also one of the most important malignant tumors in terms of incidence in Korea. In... -
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- The prognostic significance of c-erbB-2 and p53 protein expressions in gastric carcinoma: a multivariate analysis of prognostic factors
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Kim JP, Oh ST, Hwang TS, Chi JG
- KMID: 644803
- J Korean Med Sci.
- 1994 Jun;9(3):248-253.
- doi: 10.3346/jkms.1994.9.3.248
152 curative gastrectomy specimens from patients with gastric carcinoma were examined in an attempt to assess the prognostic value of c-erbB-2 and mutant p53 protein expressions. The labeled streptavidin-biotin method... -
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- Brain metastasis in human epidermal growth factor receptor 2-positive breast cancer: from biology to treatment
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Koo T, Kim IA
- KMID: 2316750
- Radiat Oncol J.
- 2016 Mar;34(1):1-9.
- doi: 10.3857/roj.2016.34.1.1
Overexpression of human epidermal growth factor receptor 2 (HER2) is found in about 20% of breast cancer patients. With treatment using trastuzumab, an anti-HER2 monoclonal antibody, systemic control is improved.... -
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