- Downregulation of Angiotensin II-Induced 12-Lipoxygenase Expression and Cell Proliferation in Vascular Smooth Muscle Cells from Spontaneously Hypertensive Rats by CCL5
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Kim JH, Kim HS
- KMID: 1982573
- Korean J Physiol Pharmacol.
- 2009 Oct;13(5):385-392.
- doi: 10.4196/kjpp.2009.13.5.385
Angiotensin II (Ang II) plays an important role in vascular hypertension. The role of the chemokine CCL5 on Ang II-induced activities in vascular smooth muscle cells (VSMCs) has not been... -
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- Angiotensin-(1-9) ameliorates pulmonary arterial hypertension via angiotensin type II receptor
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Cha SA, Park BM, Kim SH
- KMID: 2414269
- Korean J Physiol Pharmacol.
- 2018 Jul;22(4):447-456.
- doi: 10.4196/kjpp.2018.22.4.447
Angiotensin-(1-9) [Ang-(1-9)], generated from Ang I by Ang II converting enzyme 2, has been reported to have protective effects on cardiac and vascular remodeling. However, there is no report about... -
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- Sulfatase 1 mediates the inhibitory effect of angiotensin II type 2 receptor inhibitor on angiotensin II-induced hypertensive mediator expression and proliferation in vascular smooth muscle cells from spontaneously hypertensive rats
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Kim HY, Cha HJ, Kim HS
- KMID: 2400328
- Yeungnam Univ J Med.
- 2017 Jun;34(1):43-54.
- doi: 10.12701/yujm.2017.34.1.43
BACKGROUND: Extracellular sulfatases (Sulfs), sulfatase 1 (Sulf1) and sulfatase 2 (Sulf2), play a pivotal role in cell signaling by remodeling the 6-O-sulfation of heparan sulfate proteoglycans on the cell surface.... -
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- Effects of Angiotensin II Type 2 Receptor on the Fibrosis of Diabetic Heart in the Otsuka Long-Evans Tokushima Fatty (OLETF) Rat
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Choi CU, Park CG, Cha DR, Kim SH, Shin SY, Kim YK, Na JO, Kim JW, Lim HE, Kim EJ, Rha SW, Seo HS, Oh DJ
- KMID: 1750376
- J Korean Soc Hypertens.
- 2010 Dec;16(4):19-29.
BACKGROUND: The objective of this study was to determine the effects of angiotensin II type 2 (AT2) receptor on the fibrosis of the diabetic heart and the hypertrophy of the... -
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- Genetic Contributions to Childhood Obesity: Association of Candidate Gene Polymorphisms and Overweight/Obesity in Korean Preschool Children
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Yoo KH, Yim HE, Bae ES, Hong YS
- KMID: 2396377
- J Korean Med Sci.
- 2017 Dec;32(12):1997-2004.
- doi: 10.3346/jkms.2017.32.12.1997
This study was aimed to investigate the association of candidate gene polymorphisms and obesity or overweight in young Korean children. A total of 190 Korean preschool children (96 control, 48... -
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- Association of Angiotensin II Type 2 Receptor Gene A1818T Polymorphism with Progression of Immunoglobulin A Nephropathy in Korean Patients
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Yoon HJ, Chin HJ, Na KY, Chae DW, Kim S, Jeon US, Chung WK, Lee HH, Yang J, Kim S, Kwon YJ, Kim HC, Park SB, Kim HY, Lee TW, The Progressive REnal disease and Medical Informatics and gEnomics Research (PREMIER) members
- KMID: 1778138
- J Korean Med Sci.
- 2009 Jan;24(Suppl 1):S38-S43.
- doi: 10.3346/jkms.2009.24.S1.S38
We determined the relationship between the progression of immunoglobulin A nephropathy (IgAN) and the A1818T polymorphism in intron 2 of Angiotensin II type 2 receptor (AT2R) gene, which might play... -
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- Postmenopausal Hypertension and Sodium Sensitivity
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Kim JM, Kim TH, Lee HH, Lee SH, Wang T
- KMID: 2325447
- J Menopausal Med.
- 2014 Apr;20(1):1-6.
It has been well established that women generally have lower incidence rates of hypertension than men at similar ages and these differences may vary with age. It also has been... -
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- Lifestyle intervention might easily improve blood pressure in hypertensive men with the C genotype of angiotensin II type 2 receptor gene
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Kitaoka K, Kitade A, Nagaoka J, Tsuzaki K, Harada K, Aoi W, Wada S, Asano H, Sakane N, Higashi A
- KMID: 2313855
- Nutr Res Pract.
- 2015 Aug;9(4):385-392.
- doi: 10.4162/nrp.2015.9.4.385
BACKGROUND/OBJECTIVES: Recent studies have reported an association of the angiotensin II type 2 receptor (AT2R) 3123Cytosine/Adenine (3123C/A) polymorphism with essential hypertension and cardiovascular diseases. The purpose of the study was... -
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