- Is radioimmunotherapy a 'magic bullet'?
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Kim SH
- KMID: 2083598
- Korean J Hematol.
- 2012 Jun;47(2):85-86.
- doi: 10.5045/kjh.2012.47.2.85
No abstract available. -
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- Alpha-emitting Radioisotopes Production for Radioimmunotherapy
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Chun KS
- KMID: 1512509
- Nucl Med Mol Imaging.
- 2007 Feb;41(1):1-8.
This review discusses the production of alpha-particle-emitting radionuclides in radioimmunotherapy. Radioimmunotherapy labeled with alpha-particle is expected to be very useful for the treatment of monocellular cancer (e.g. leukemia) and micrometastasis... -
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- Stability of 188Re Labeled Antibody for Radioimmunotherapy and the Effect of Stabilizing Agents
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Chang YS, Kim BK, Jeong JM, Chung JK, Lee SJ, Lee DS, Lee MC
- KMID: 1647833
- Korean J Nucl Med.
- 2002 Jun;36(3):195-202.
No abstract available. -
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- Radioimmunotherapy (I): Development of Radioimmunoconjugates
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Choi TH, Lim SM
- KMID: 2313015
- Nucl Med Mol Imaging.
- 2006 Apr;40(2):66-73.
Monoclonal antibodies are designed to bind specifically to certain antigen, give therapeutic effect to the target and to be produced in large scale with homogeneity. The monoclonal antibodies conjugated with... -
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- Radioimmunotherapy (RIT) in Brain Tumors
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Gholamrezanezhad A, Shooli H, Jokar N, Nemati R, Assadi M
- KMID: 2469580
- Nucl Med Mol Imaging.
- 2019 Dec;53(6):374-381.
- doi: 10.1007/s13139-019-00618-6
Annually, the incidence of brain tumors has slightly increased and also the patient prognosis is still disappointing, especially for high-grade neoplasms. So, researchers seek methods to improve therapeutic index as... -
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- Radioimmunotherapy (II): Clinical Application
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Cheon GJ, Kang HJ, Lim SM
- KMID: 2313016
- Nucl Med Mol Imaging.
- 2006 Apr;40(2):74-81.
Molecular targeting may be defined as the specific concentration of a diagnostic or therapeutic tracer by its interaction with a molecular species that is distinctly present or absent in a... -
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- Radioimmunotherapy in Head and Neck Cancer
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Choi IJ
- KMID: 2430840
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2018 Dec;61(12):637-643.
- doi: 10.3342/kjorl-hns.2018.00696
Radioimmunotherapy (RIT) is a therapy that takes advantage of the “cross-fire†effect of emitted radiation by radionuclides conjugated to tumor-directed monoclonal antibodies (mAb) (including those fragments) or peptides. While RIT... -
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- Radioimmunotherapy with 131I-Rituximab in a Patient with Diffuse Large B-Cell Lymphoma Relapsed After Treatment with 90Y-Ibritumomab Tiuxetan
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Kang GW, Kang HJ, Shin DY, Gu HR, Choi HS, Lim SM
- KMID: 2313169
- Nucl Med Mol Imaging.
- 2013 Dec;47(4):281-284.
We report a case that demonstrates the efficacy of radioimmunotherapy (RIT) with radioiodinated rituximab (131I-rituximab) for relapsed diffuse large B-cell lymphoma (DLBCL). A 79-year-old male patient with DLBCL initially achieved... -
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- Measurement of Tumor Pressure and Strategies of Imaging Tumor Pressure for Radioimmunotherapy
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Kim HG, Yu AR, Lee JJ, Lee YJ, Lim SM, Kim JS
- KMID: 2455517
- Nucl Med Mol Imaging.
- 2019 Aug;53(4):235-241.
- doi: 10.1007/s13139-019-00598-7
Tumor interstitial pressure is a fundamental feature of cancer biology. Elevation in tumor pressure affects the efficacy of cancer treatment and results in the heterogenous intratumoral distribution of drugs and... -
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- Combination Radioimmunotherapy Approaches and Quantification of Immuno-PET
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Kim JS
- KMID: 2256997
- Nucl Med Mol Imaging.
- 2016 Jun;50(2):104-111.
- doi: 10.1007/s13139-015-0392-7
Monoclonal antibodies (mAbs), which play a prominent role in cancer therapy, can interact with specific antigens on cancer cells, thereby enhancing the patient's immune response via various mechanisms, or mAbs... -
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- mage-Based Assessment and Clinical Significance of Absorbed Radiation Dose to Tumor in Repeated High-Dose (131)I Anti-CD20 Monoclonal Antibody (Rituximab) Radioimmunotherapy for Non-Hodgkin's Lymphoma
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Byun BH, Kim KM, Woo SK, Choi TH, Kang HJ, Oh DH, Kim BI, Cheon GJ, Choi CW, Lim SM
- KMID: 2313071
- Nucl Med Mol Imaging.
- 2009 Feb;43(1):60-71.
PURPOSE: We assessed the absorbed dose to the tumor (Dosetumor) by using pretreatment FDG-PET and whole-body (WB) planar images in repeated radioimmunotherapy (RIT) with 131I rituximab for NHL. MATERIALS AND METHODS:... -
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- In Vitro Properties and Biodistribution of Tc-99m and Re-188 Labeled Monoclonal Antibody CEA79.4
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Hong MK, Jeong JM, Yeo JS, Kim KM, Chang YS, Lee YJ, Lee DS, Chung JK, Lee MC, Lee SJ
- KMID: 1566918
- Korean J Nucl Med.
- 1998 Dec;32(6):516-524.
PURPOSE: Radiolabeled CEA79.4 antibody has a possibility to be used in radioimmunoscintigraphy or radioimmunotheraphy of cancer. We investigated the in vitro properties and biodistribution of CEA79.4 antibody labeled with Re-188... -
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- Novel biological strategies to enhance the radiation therapeutic ratio
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Kim JH, Jenrow KA, Brown SL
- KMID: 2426293
- Radiat Oncol J.
- 2018 Sep;36(3):172-181.
- doi: 10.3857/roj.2018.00332
Successful anticancer strategies require a differential response between tumor and normal tissue (i.e., a therapeutic ratio). In fact, improving the effectiveness of a cancer therapeutic is of no clinical value... -
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- Consolidation and maintenance therapy for patients with advanced epithelial ovarian cancer
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Kim SC
- KMID: 2272696
- Korean J Obstet Gynecol.
- 2005 Oct;48(10):2261-2284.
The current therapy for patients with advanced ovarian cancer consists of maximal cytoreductive surgery followed by six cycles of combination chemotherapy with paclitaxel/carboplatin. With this therapy, approximately 75% of patients... -
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- Review of Radionuclide Treatment for Neuroendocrine Tumors
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Jeong HJ
- KMID: 2313018
- Nucl Med Mol Imaging.
- 2006 Apr;40(2):90-95.
Neuroendocrine tumors (NETs) consist of a heterogeneous group of tumors that are able to uptake neuroamine and/or specific receptors, such as somatostatin receptors, which can play important roles of the... -
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- Evaluation of the Radioimmunotherapy Using I-131 Labeled Vascular Endothelial Growth Factor Receptor2 Antibody in Melanoma Xenograft Murine Model
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Kim EM, Jeong HJ, Park EH, Cheong SJ, Lee CM, Jang K, Kim DW, Lim ST, Sohn MH
- KMID: 2313058
- Nucl Med Mol Imaging.
- 2008 Aug;42(4):307-313.
PURPOSE: Vascular endothelial growth factor (VEGF) and its receptor, fetal liver kinase 1 (Flk-1), play an important role in vascular permeability and tumor angiogenesis. The aim of this study is... -
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- Transcatheter Arterial Chemoembolization Plus ¹³¹I-Labelled Metuximab versus Transcatheter Arterial Chemoembolization Alone in Intermediate/Advanced Stage Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis
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Zhu ZX, Liao MH, Wang XX, Huang JW
- KMID: 2466285
- Korean J Radiol.
- 2016 Dec;17(6):882-892.
- doi: 10.3348/kjr.2016.17.6.882
OBJECTIVE: The aim of the study was to compare transcatheter arterial chemoembolization (TACE) plus ¹³¹I-labelled metuximab with TACE alone for hepatocellular carcinoma (HCC). MATERIALS AND METHODS: A comprehensive search was conducted... -
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- Yttrium-90 ibritumomab tiuxetan plus busulfan, cyclophosphamide, and etoposide (BuCyE) versus BuCyE alone as a conditioning regimen for non-Hodgkin lymphoma
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Jo JC, Yoon DH, Kim S, Park JS, Park CS, Huh J, Lee SW, Ryu JS, Suh C
- KMID: 2083605
- Korean J Hematol.
- 2012 Jun;47(2):119-125.
- doi: 10.5045/kjh.2012.47.2.119
BACKGROUND: Radioimmunotherapy agents have a highly significant role in autologous stem cell transplantation as they improve tolerability and increase the efficacy of the conditioning regimen. METHODS: We retrospectively analyzed the efficacy... -
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- Comparative Quantitative Analysis of Cluster of Differentiation 45 Antigen Expression on Lymphocyte Subsets
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Im M, Chae H, Kim T, Park HH, Lim J, Oh EJ, Kim Y, Park YJ, Han K
- KMID: 1735845
- Korean J Lab Med.
- 2011 Jul;31(3):148-153.
- doi: 10.3343/kjlm.2011.31.3.148
BACKGROUND: Since the recent introduction of radioimmunotherapy (RIT) using antibodies against cluster of differentiation (CD) 45 for the treatment of lymphoma, the clinical significance of the CD45 antigen has been... -
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- Stereotactic Body Radiotherapy: Does It Have a Role in Management of Hepatocellular Carcinoma?
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Choi SH, Seong J
- KMID: 2419724
- Yonsei Med J.
- 2018 Oct;59(8):912-922.
- doi: 10.3349/ymj.2018.59.8.912
Stereotactic body radiotherapy (SBRT) is a form of radiotherapy that delivers high doses of irradiation with high precision in a small number of fractions. However, it has not frequently been... -
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