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Mitochondrial Quality Control in the Heart: New Drug Targets for Cardiovascular Disease

Oh CM, Ryu D, Cho S, Jang Y

Despite considerable efforts to prevent and treat cardiovascular disease (CVD), it has become the leading cause of death worldwide. Cardiac mitochondria are crucial cell organelles responsible for creating energy-rich ATP...
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Recharacterization of the Canine Adenovirus Type 1 Vaccine Strain based on the Biological and Molecular Properties

Yang DK, Kim HH, Lee EJ, Yoo JY, Yoon SS, Park J, Kim CH, Kim HR

Canine adenovirus type 1 (CAV-1) infection results in hepatitis in dogs. In this study, we investigated the biologic and genetic characteristics of the CAV-1 vaccine strain (CAV1V) to improve quality...
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Updates on the Disinfection and Infection Control Process of the Accredited Endoscopy Unit

Shin JE, Jung Y, Lee JH, Son BK, Jang JY, Kim HK, Jang BI, The Quality Management Committee and the Disinfection Management Committee of Korean Society of Gastrointestinal Endoscopy

A thorough disinfection and infection control process associated with gastrointestinal endoscopy is highly important for the health and safety of the examinee and the medical staff involved in the procedure....
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Accredited Endoscopy Unit Program of Korea: Overview and Qualification

Kim JW, Cho YK, Kim JO, Jang JY, the Quality Management Committee of Korean Society of Gastrointestinal Endoscopy

The Korean Society of Gastrointestinal Endoscopy introduced the Accredited Endoscopy Unit Program to enhance endoscopy unit quality through systematic quality management in 2012. It was gradually expanded from training hospitals...
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Comparison of the MGISEQ-2000 and Illumina HiSeq 4000 sequencing platforms for RNA sequencing

Jeon SA, Park JL, Kim JH, Kim JH, Kim YS, Kim JC, Kim SY

Currently, Illumina sequencers are the globally leading sequencing platform in the next-generation sequencing market. Recently, MGI Tech launched a series of new sequencers, including the MGISEQ-2000, which promise to deliver...
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Production and Performance Evaluation of External Quality Assessment Materials for Human Epididymis Protein 4 Assay

Lee A, Kim HJ

BACKGROUND: External quality assessment (EQA) is important for standardizing cancer biomarker assays, thereby, ensuring accurate and precise results. Although the human epididymis-specific protein 4 (HE4) assay has been increasingly used...
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A Survey on Current Trends of Breast Imaging Practices in Korea

Yun BL, Kim SM, Jang M, Cho N, Han BK

PURPOSE: This study aimed to analyze the current practices of breast imaging among Korean radiologists. MATERIALS AND METHODS: We invited members of the Korean Society of Breast Imaging (KSBI) working as...
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National Lung Cancer Screening in Korea: Introduction and Imaging Quality Control

Kim HY

Before the implementation of lung cancer screening as a national cancer screening program, the Korean Lung Cancer Screening Project was performed to evaluate its effectiveness and feasibility. A national lung...
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Evaluation of the Analytical Performance of Atellica CH 930 Automated Chemistry Analyzer

Kim D, Cho Y, Cho J, Kim SH, Lee SG, Kim JH

BACKGROUND: Recently, a new automated chemistry analyzer, Atellica CH930 (Siemens, Germany), was introduced. It automatically measures internal quality control (QC) materials according to a pre-determined schedule. For this purpose, the...
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Mitochondrial Dysfunction in Adipocytes as a Primary Cause of Adipose Tissue Inflammation

Woo CY, Jang JE, Lee SE, Koh EH, Lee KU

Adipose tissue inflammation is considered a major contributing factor in the development of obesity-associated insulin resistance and cardiovascular diseases. However, the cause of adipose tissue inflammation is presently unclear. The...
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Simultaneous Analysis of Four Standards of The Herbal Formula, DF-02, of Ephedra intermedia and Rheum palmatum, using by High Performance Liquid Chromatography-Ultraviolet Detector (HPLC-UVD)

Choi SY, Jeong B, Jang HS, Lee J, Kwon YS, Yoon Y, Shin SS, Yang H

The herbal formula, DF-02, consisting of Ephedra intermedia and Rheum palmatum are used for the treatment of the metabolic diseases such as obesity and liver fibrosis in Korean local clinics....
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Analyses of the Proficiency Testing Program and the Performance of Qualitative Reagents for Rheumatoid Factor

Oh J, Park HD

BACKGROUND: Rheumatoid factor (RF) is used as one of the diagnostic criteria for rheumatoid arthritis. The purpose of this study was to evaluate qualitative RF reagents used in clinical laboratories...
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Report of the Korean Association of External Quality Assessment Service on Clinical Mycobacteriology (2017–2018)

Shin S, Hong SH

Rapid and correct diagnosis is essential for national tuberculosis (TB) control. A greater national concern for quality control (QC) of Mycobacterium tuberculosis (MTB) testing is required to improve the proficiency...
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Annual Report of the Korean Association of External Quality Assessment Service on Urinalysis and Fecal Occult Blood Testing (2018)

Jeon CH, Lee AJ, Kim SG, Suh HS, Bae YC

In 2018, external quality assessment trials for urinalysis and fecal occult blood (FOB) were performed using 1,590 participants. Urine chemistry tests were performed thrice while urine sediment and FOB tests...
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Factors affecting modulation transfer function measurements in cone-beam computed tomographic images

Choi JW

PURPOSE: This study was designed to investigate the effects of voxel size, the oversampling technique, and the direction and area of measurement on modulation transfer function (MTF) values to identify...
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Established and Emerging Mechanisms of Diabetic Cardiomyopathy

Gollmer J, Zirlik A, Bugger H

Diabetes mellitus increases the risk for the development of heart failure even in the absence of coronary artery disease and hypertension, a cardiac entity termed diabetic cardiomyopathy (DC). Clinically, DC...
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SETD2, GIGYF2, FGFR3, BCR, KMT2C, and TSC2 as candidate genes for differentiating multilocular cystic renal neoplasm of low malignant potential from clear cell renal cell carcinoma with cystic change

Kim SH, Park WS, Chung J

PURPOSE: Multilocular cystic renal neoplasm of low malignant potential (MCRNLMP) and clear cell renal cell carcinoma with cystic change (MCRCC) have different prognoses despite similar histologic characteristics. The aim of...
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Interobserver agreement in breast ultrasound categorization in the Mammography and Ultrasonography Study for Breast Cancer Screening Effectiveness (MUST-BE) trial: results of a preliminary study

Choi EJ, Lee EH, Kim YM, Chang YW, Lee JH, Park YM, Kim KW, Kim YJ, Jun JK, Hong S

PURPOSE: The purpose of this study was to record and evaluate interobserver agreement as quality control for the modified categorization of screening breast ultrasound developed by the Alliance for Breast...
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Guideline on safety evaluation of cell-based medicinal products for animal use

Ku HO, Yi H, Park YI, Jeon BS, Kang HG, Kim YS, Park BK

With the increased use of cell therapy in the veterinary sector, there is a growing demand for the development of cell-based medicinal products and the determination of their safety. Currently,...
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Achievements, Problems, and Future Direction of the Quality Control Program for Special Periodic Health Examination Agencies in Republic of Korea

Won YL, Ko KS, Park JO, Choi YJ, Lee H, Sung JM, Lee MY

The ultimate goal of the quality control program for special periodic health examination agencies is to diagnose the health condition of a worker correctly, based on accurate examination and analysis...
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