- The Efficacy of Vildagliptin in Korean Patients with Type 2 Diabetes
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Moon JS, Won KC
- KMID: 2280740
- Diabetes Metab J.
- 2013 Feb;37(1):36-39.
- doi: 10.4093/dmj.2013.37.1.36
No abstract available. -
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- Comparison of DPP-4 Inhibitors
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Kim NH, Kim SG
- KMID: 2173918
- J Korean Diabetes.
- 2013 Sep;14(3):111-119.
- doi: 10.4093/jkd.2013.14.3.111
During past several years, a novel class of antihyperglycemic agents, dipeptidyl peptidase-4 (DPP-4) inhibitors, has become one of the most important options in the management of type 2 diabetes. These... -
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- Enhanced Expression of Glucose 2-Oxidase in Phlebia tremellosa by Addition of Phthalates
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Kim B, Kim H, Choi HT
- KMID: 2312616
- Mycobiology.
- 2011 Mar;39(1):64-66.
Most fungi possess several hydrogen peroxide-generating enzymes, glucose oxidase and pyranose oxidase. Pyranose oxidase can use glucose as its substrate to generate hydrogen peroxide. White rot fungi, which degrade diverse... -
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- New Therapeutics for Diabetes Using Incretin Hormone
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Oh S
- KMID: 2259281
- Korean J Med.
- 2011 Jun;80(6):625-634.
New therapeutics for type 2 diabetes using incretin hormone were introduced recently. Incretin-based therapies consist of two types: GLP-1 agonists mainly acting on the GLP-1 receptor and dipeptidyl peptidase 4... -
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- Incretin-based Combination Therapy in Type 2 Diabetes Mellitus
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Kim JH, Lee MS
- KMID: 2188084
- J Korean Med Assoc.
- 2009 Oct;52(10):1030-1036.
- doi: 10.5124/jkma.2009.52.10.1030
While there are many therapies for type 2 diabetes are available including insulin secretagogues, insulin sensitizers and exogenous insulin, many patients are unable to reach recommended therapeutic targets. Incretin-based therapies... -
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- Comparison of Emotional and Psychological Characteristics between Suicide Attempters and Non-Attempters in Depressed Patients : Using MMPI-2 Profiles
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Lee SA, Kim KH, Suh SY
- KMID: 1436078
- Korean J Psychosom Med.
- 2012 Jun;20(1):40-49.
OBJECTIVES: To examine emotional and psychological characteristics associated with suicide attempts in depressed patients. METHODS: A sample of 37 inpatients diagnosed with major depressive disorder or depressive disorder NOS was divided... -
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- Zinc Inhibits Amyloid beta Production from Alzheimer's Amyloid Precursor Protein in SH-SY5Y Cells
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Lee J, Kim CH, Kim DG, Ahn YS
- KMID: 2071671
- Korean J Physiol Pharmacol.
- 2009 Jun;13(3):195-200.
- doi: 10.4196/kjpp.2009.13.3.195
Zinc released from excited glutamatergic neurons accelerates amyloid beta (A beta) aggregation, underscoring the therapeutic potential of zinc chelation for the treatment of Alzheimer's disease (AD). Zinc can also alter... -
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- Differences in Clinical and Psychological Characteristics between Patients with Borderline Personality Disorder and Depression
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Kwan JH, Chang MS, Kwak HW, Koo BH
- KMID: 2316680
- Psychoanalysis.
- 2011 Oct;22(2):106-115.
OBJECTIVES: There has been little research into comparing characteristics of the patients with borderline personality disorder (BPD) and depression (DEP) which can often be encountered in clinical settings. This study... -
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- Rationale for the Use of Anticholinergic Agents in Overactive Bladder With Regard to Central Nervous System and Cardiovascular System Side Effects
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Cetinel B, Onal B
- KMID: 2315935
- Korean J Urol.
- 2013 Dec;54(12):806-815.
PURPOSE: Central nervous system (CNS) and cardiovascular system (CVS) side effects of anticholinergic agents used to treat overactive bladder (OAB) are underreported. Hence, this review aimed to focus on the... -
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- Predictive Clinical Parameters and Glycemic Efficacy of Vildagliptin Treatment in Korean Subjects with Type 2 Diabetes
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Chang JS, Shin J, Kim HS, Kim KH, Shin JA, Yoon KH, Cha BY, Son HY, Cho JH
- KMID: 2280745
- Diabetes Metab J.
- 2013 Feb;37(1):72-80.
- doi: 10.4093/dmj.2013.37.1.72
BACKGROUND: The aims of this study are to investigate the glycemic efficacy and predictive parameters of vildagliptin therapy in Korean subjects with type 2 diabetes. METHODS: In this retrospective study, we... -
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- Comparison of Vildagliptin-Metformin and Glimepiride-Metformin Treatments in Type 2 Diabetic Patients
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Jeon HJ, Oh TK
- KMID: 1857509
- Diabetes Metab J.
- 2011 Oct;35(5):529-535.
- doi: 10.4093/dmj.2011.35.5.529
BACKGROUND: The present study investigated the efficacy and safety of vildagliptin-metformin treatment compared to those of glimepiride-metformin treatment for type 2 diabetes. METHODS: In a randomized, open-label, comparative study, 106 patients... -
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- DPP-4 Inhibitors and the Relations between Rosiglitazone and the Risk of Myocardial Infarction
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Lee HW
- KMID: 2185748
- J Korean Med Assoc.
- 2008 Apr;51(4):371-376.
- doi: 10.5124/jkma.2008.51.4.371
If the type 2 diabetes is left untreated, it can eventually be lead to vascular complications, including nephropathy, retinopathy, neuropathy, coronary heart disease, and CVA. The current antidiabetic drugs are... -
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- The Relaxing Effect of alpha-Defensin 1 on the Adrenergic Responses of Rat Bladder
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Lee SY, Kim DK, Kim KD, Myung SC, Lee MY
- KMID: 1448917
- Korean J Physiol Pharmacol.
- 2011 Jun;15(3):143-147.
- doi: 10.4196/kjpp.2011.15.3.143
Defensins, cysteine-rich cationic polypeptides released from neutrophils, are known to have powerful antimicrobial properties. In this study, we sacrificed 30 rats to investigate the effects of alpha-defensin 1 on detrusor... -
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- Pyrrolidine Dithiocarbamate Inhibits Nuclear Factor kappaB and Toll-Like Receptor 4 Expression in Rats with Acute Necrotizing Pancreatitis
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Xu M, Wang KN, Wu K, Wang XP
- KMID: 2155650
- Gut Liver.
- 2015 May;9(3):411-416.
- doi: 10.5009/gnl14050
BACKGROUND/AIMS: To investigate the expression of Toll-like receptor 4 (TLR4) in the pancreases of rats with acute necrotizing pancreatitis (ANP) and any changes upon treatment with pyrrolidine dithiocarbamate (PDTC), an... -
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- Clinical Characteristics of the Responders to Dipeptidyl Peptidase-4 Inhibitors in Korean Subjects with Type 2 Diabetes
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Oh TJ, Jung HS, Bae JH, Kim YG, Park KS, Cho YM, Park KS, Kim SY
- KMID: 2158036
- J Korean Med Sci.
- 2013 Jun;28(6):881-887.
- doi: 10.3346/jkms.2013.28.6.881
We investigated characteristics associated with the efficacy of dipeptidyl peptidase-4 inhibitors (DPP4i) in Korean patients with type 2 diabetes. We reviewed medical records of 477 patients who had taken sitagliptin... -
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- Effects of all-trans retinoic acid on expression of Toll-like receptor 5 on immune cells
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Kim KH, Park SJ
- KMID: 2328585
- J Korean Assoc Oral Maxillofac Surg.
- 2010 Dec;36(6):481-489.
INTRODUCTION: TLR-5, a member of the toll-like receptor (TLR) family, is a element of the type I transmembrane receptors, which are characterized by an intracellular signaling domain homolog to the... -
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- Corn silk induces nitric oxide synthase in murine macrophages
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Kim KA, Choi SK, Choi HS
- KMID: 1103321
- Exp Mol Med.
- 2004 Dec;36(6):545-550.
Corn silk has been purified as an anticoagulant previously and the active component is a polysaccharide with a molecular mass of 135 kDa. It activates murine macrophages to induce nitric... -
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